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- W2109758717 abstract "Substituted 3-aminopiperidines 3 were evaluated as DPP-4 inhibitors. The inhibitors showed good DPP-4 potency with superb selectivity over other peptidases (QPP, DPP8, and DPP9). Selected DPP-4 inhibitors were further evaluated for their hERG potassium channel, calcium channel, Cyp2D6, and pharmacokinetic profiles." @default.
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- W2109758717 date "2007-08-01" @default.
- W2109758717 modified "2023-10-14" @default.
- W2109758717 title "Discovery of 3-aminopiperidines as potent, selective, and orally bioavailable dipeptidyl peptidase IV inhibitors" @default.
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- W2109758717 doi "https://doi.org/10.1016/j.bmcl.2007.05.087" @default.
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