FRINK Linked Data Fragments server

Matches in SemOpenAlex for { <https://semopenalex.org/work/W2118047561> ?p ?o ?g. }

• W2118047561 endingPage "1335" @default.
• W2118047561 startingPage "1324" @default.
• W2118047561 abstract "Cobalamin (vitamin B-12) and cobalamin analogues are present in human feces, but a complete identification has not been established, and the amounts present have not been determined. We aimed to develop a liquid chromatography–mass spectrometry method for cobalamin and cobalamin analogues and to identify and quantitiate the amounts present in human feces. Fecal samples were obtained from 20 human subjects in good general health. The samples were analyzed for the presence and amounts of cobalamin and 12 cobalamin analogues that were synthesized with and without the incorporation of stable isotopes. Cobalamin and 7 cobalamin analogues were identified and quantitated in human feces. The mean for the total amount present in 18 subjects whose daily intake was ≤25 μg cobalamin from vitamin supplements was 1309 ng cobalamin equivalents/g wet wt of feces. Cobalamin (1.4%) and cobinamide (1.8%) (an incomplete corrinoid) represented a small portion of the total amount. Six cobalamin analogues that contain a base other than the 5,6-dimethylbenzimidizidole in cobalamin were present. The bases and their mean amounts (in %) are 2-methyladenine (60.6%), p-cresol (16.3%), adenine (12.5%), 2-(methylthio)adenine (15.5%), 5-hydroxybenzimidazole (1.8%), and phenol (0.1%). One subject ingested 1 mg cobalamin/d and another ingested 2 mg cobalamin/d, and they appeared to convert most of the cobalamin to cobinamide and the 4 analogues that contain the bases—2-methyladenine, p-cresol, adenine, and 2-(methylthio)adenine. Cobalamin analogues are present in human feces and account for >98% of the total of cobalamin plus cobalamin analogues. A major portion of large amounts of ingested cobalamin appears to be converted to cobalamin analogues." @default.
• W2118047561 created "2016-06-24" @default.
• W2118047561 creator A5013709045 @default.
• W2118047561 creator A5056996183 @default.
• W2118047561 date "2008-05-01" @default.
• W2118047561 modified "2023-10-11" @default.
• W2118047561 title "Identification and quantitation of cobalamin and cobalamin analogues in human feces" @default.
• W2118047561 cites W139556733 @default.
• W2118047561 cites W1530261762 @default.
• W2118047561 cites W1561679936 @default.
• W2118047561 cites W1737562535 @default.
• W2118047561 cites W1817295519 @default.
• W2118047561 cites W1839631757 @default.
• W2118047561 cites W1980914602 @default.
• W2118047561 cites W1984199829 @default.
• W2118047561 cites W2017771146 @default.
• W2118047561 cites W2034781901 @default.
• W2118047561 cites W2035985317 @default.
• W2118047561 cites W2054482694 @default.
• W2118047561 cites W2062655244 @default.
• W2118047561 cites W2074274422 @default.
• W2118047561 cites W2080896769 @default.
• W2118047561 cites W2088078353 @default.
• W2118047561 cites W2104579086 @default.
• W2118047561 cites W2124378315 @default.
• W2118047561 cites W2132980988 @default.
• W2118047561 cites W2145336165 @default.
• W2118047561 cites W2161784662 @default.
• W2118047561 cites W2328023807 @default.
• W2118047561 cites W2400322578 @default.
• W2118047561 cites W4285719527 @default.
• W2118047561 cites W79140663 @default.
• W2118047561 doi "https://doi.org/10.1093/ajcn/87.5.1324" @default.
• W2118047561 hasPubMedCentralId "https://www.ncbi.nlm.nih.gov/pmc/articles/2900183" @default.
• W2118047561 hasPubMedId "https://pubmed.ncbi.nlm.nih.gov/18469256" @default.
• W2118047561 hasPublicationYear "2008" @default.
• W2118047561 type Work @default.
• W2118047561 sameAs 2118047561 @default.
• W2118047561 citedByCount "130" @default.
• W2118047561 countsByYear W21180475612012 @default.
• W2118047561 countsByYear W21180475612013 @default.
• W2118047561 countsByYear W21180475612014 @default.
• W2118047561 countsByYear W21180475612015 @default.
• W2118047561 countsByYear W21180475612016 @default.
• W2118047561 countsByYear W21180475612017 @default.
• W2118047561 countsByYear W21180475612018 @default.
• W2118047561 countsByYear W21180475612019 @default.
• W2118047561 countsByYear W21180475612020 @default.
• W2118047561 countsByYear W21180475612021 @default.
• W2118047561 countsByYear W21180475612022 @default.
• W2118047561 countsByYear W21180475612023 @default.
• W2118047561 crossrefType "journal-article" @default.
• W2118047561 hasAuthorship W2118047561A5013709045 @default.
• W2118047561 hasAuthorship W2118047561A5056996183 @default.
• W2118047561 hasBestOaLocation W21180475611 @default.
• W2118047561 hasConcept C104317684 @default.
• W2118047561 hasConcept C185592680 @default.
• W2118047561 hasConcept C2776940978 @default.
• W2118047561 hasConcept C2777392542 @default.
• W2118047561 hasConcept C2779750884 @default.
• W2118047561 hasConcept C2780676250 @default.
• W2118047561 hasConcept C2780829489 @default.
• W2118047561 hasConcept C2781148582 @default.
• W2118047561 hasConcept C33288867 @default.
• W2118047561 hasConcept C43617362 @default.
• W2118047561 hasConcept C55493867 @default.
• W2118047561 hasConcept C61716771 @default.
• W2118047561 hasConcept C86803240 @default.
• W2118047561 hasConcept C89423630 @default.
• W2118047561 hasConcept C91965660 @default.
• W2118047561 hasConceptScore W2118047561C104317684 @default.
• W2118047561 hasConceptScore W2118047561C185592680 @default.
• W2118047561 hasConceptScore W2118047561C2776940978 @default.
• W2118047561 hasConceptScore W2118047561C2777392542 @default.
• W2118047561 hasConceptScore W2118047561C2779750884 @default.
• W2118047561 hasConceptScore W2118047561C2780676250 @default.
• W2118047561 hasConceptScore W2118047561C2780829489 @default.
• W2118047561 hasConceptScore W2118047561C2781148582 @default.
• W2118047561 hasConceptScore W2118047561C33288867 @default.
• W2118047561 hasConceptScore W2118047561C43617362 @default.
• W2118047561 hasConceptScore W2118047561C55493867 @default.
• W2118047561 hasConceptScore W2118047561C61716771 @default.
• W2118047561 hasConceptScore W2118047561C86803240 @default.
• W2118047561 hasConceptScore W2118047561C89423630 @default.
• W2118047561 hasConceptScore W2118047561C91965660 @default.
• W2118047561 hasIssue "5" @default.
• W2118047561 hasLocation W21180475611 @default.
• W2118047561 hasLocation W21180475612 @default.
• W2118047561 hasLocation W21180475613 @default.
• W2118047561 hasLocation W21180475614 @default.
• W2118047561 hasOpenAccess W2118047561 @default.
• W2118047561 hasPrimaryLocation W21180475611 @default.
• W2118047561 hasRelatedWork W2012308239 @default.
• W2118047561 hasRelatedWork W2073528223 @default.
• W2118047561 hasRelatedWork W2100491717 @default.
• W2118047561 hasRelatedWork W2104489105 @default.
• W2118047561 hasRelatedWork W2112437452 @default.
• W2118047561 hasRelatedWork W2118047561 @default.

• next