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- W2129642416 abstract "Summary A prospective randomized matched pair study was designed to test the efficacy of the peritoneovenous (LeVeen) shunt as a treatment for massive cirrhotic ascites compared with traditional medical therapy. Patients who failed to lose weight while on a low salt diet and fluids restricted to 1000 ml daily were placed in the study group. Weight loss, decrease in abdominal girth and diuresis were significantly greater (P < 0·01) for surgical patients than for their medically treated counterparts. The surgical technique is simple, quick and inexpensive. The surgical patients outlived their matched partners in 12 of 14 pairs where a definitive comparison was possible (P < 0·02). The median stay in hospital after randomization was shortened from 32 days with medical therapy to 15 days for those undergoing the shunt operation. Those treated medically experienced a significant rise in mean blood urea nitrogen and K+ (P < 0·02). Patients with alcoholic hepatitis, hyperbilirubinaemia (bilirubin > 154 m̈mol/l), peritoneal sepsis, severe coagulopathy and those who had recently bled from oesophageal varices are poor risks for the surgical procedure." @default.
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- W2129642416 date "1979-09-01" @default.
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- W2129642416 title "Randomized prospective matched pair study comparing peritoneovenous shunt and conventional therapy in massive ascites" @default.
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- W2129642416 doi "https://doi.org/10.1002/bjs.1800660924" @default.
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