FRINK Linked Data Fragments server

Matches in SemOpenAlex for { <https://semopenalex.org/work/W2143458171> ?p ?o ?g. }

• W2143458171 abstract "Obesity-related inflammation may have a causal role in the development of diabetes and insulin resistance, and studies using animal models of chronic experimental endotoxemia have shown the link. However, many studies use only males, and much less is known about the role of obesity-related inflammation in females. Therefore, we addressed how experimentally induced chronic inflammation affects body mass, energy intake, and glucose metabolism in female rats. Adult female Sprague Dawley rats were instrumented with slow release pellets that delivered a constant daily dose of 53 or 207 μg of lipopolysaccharide (LPS) per rat for 60 days. Control rats were instrumented with vehicle pellets. Due to inflammatory nature of high-fat diet (HFD) half of the rats received HFD (60% of calories from lard), while the other half remained on control diet to detect possible interactions between two modes of induced inflammation. Our results showed that chronic LPS administration increased female rat body mass and calorie intake in a dose-dependent manner, and that HFD further exacerbated these effects. Despite these effects, no effects of LPS and HFD were evident on female rat glucose metabolism. Only LPS elevated expression of inflammatory markers in the hypothalamus. To conclude, female rats respond to experimentally induced chronic inflammation by increasing body mass, but do not develop glucose intolerance in the given period of time." @default.
• W2143458171 created "2016-06-24" @default.
• W2143458171 creator A5012173155 @default.
• W2143458171 creator A5026488520 @default.
• W2143458171 creator A5046215043 @default.
• W2143458171 creator A5049272893 @default.
• W2143458171 creator A5062999838 @default.
• W2143458171 creator A5064074824 @default.
• W2143458171 date "2015-11-01" @default.
• W2143458171 modified "2023-09-27" @default.
• W2143458171 title "Chronic exposure to low doses of lipopolysaccharide and high-fat feeding increases body mass without affecting glucose tolerance in female rats" @default.
• W2143458171 cites W1524519714 @default.
• W2143458171 cites W1831268717 @default.
• W2143458171 cites W1869593608 @default.
• W2143458171 cites W1964562779 @default.
• W2143458171 cites W1981851376 @default.
• W2143458171 cites W1985236996 @default.
• W2143458171 cites W1991264488 @default.
• W2143458171 cites W1995375315 @default.
• W2143458171 cites W2005278702 @default.
• W2143458171 cites W2013782720 @default.
• W2143458171 cites W2017712441 @default.
• W2143458171 cites W2018135697 @default.
• W2143458171 cites W2027740042 @default.
• W2143458171 cites W2030528454 @default.
• W2143458171 cites W2031882974 @default.
• W2143458171 cites W2034137314 @default.
• W2143458171 cites W2039663505 @default.
• W2143458171 cites W2040733203 @default.
• W2143458171 cites W2042430084 @default.
• W2143458171 cites W2042518030 @default.
• W2143458171 cites W2044227830 @default.
• W2143458171 cites W2053578281 @default.
• W2143458171 cites W2055388500 @default.
• W2143458171 cites W2059041901 @default.
• W2143458171 cites W2060116667 @default.
• W2143458171 cites W2060454917 @default.
• W2143458171 cites W2062835892 @default.
• W2143458171 cites W2075290042 @default.
• W2143458171 cites W2095556872 @default.
• W2143458171 cites W2096442585 @default.
• W2143458171 cites W2102624735 @default.
• W2143458171 cites W2105423509 @default.
• W2143458171 cites W2108904664 @default.
• W2143458171 cites W2114616866 @default.
• W2143458171 cites W2115012087 @default.
• W2143458171 cites W2118004416 @default.
• W2143458171 cites W2129316761 @default.
• W2143458171 cites W2129917444 @default.
• W2143458171 cites W2131536322 @default.
• W2143458171 cites W2136518857 @default.
• W2143458171 cites W2154127252 @default.
• W2143458171 cites W2154696002 @default.
• W2143458171 cites W2156280702 @default.
• W2143458171 cites W2156441364 @default.
• W2143458171 cites W2159001939 @default.
• W2143458171 cites W2159581380 @default.
• W2143458171 cites W2163230336 @default.
• W2143458171 cites W2164636550 @default.
• W2143458171 cites W2166449272 @default.
• W2143458171 cites W4236273750 @default.
• W2143458171 doi "https://doi.org/10.14814/phy2.12584" @default.
• W2143458171 hasPubMedCentralId "https://www.ncbi.nlm.nih.gov/pmc/articles/4673625" @default.
• W2143458171 hasPubMedId "https://pubmed.ncbi.nlm.nih.gov/26537342" @default.
• W2143458171 hasPublicationYear "2015" @default.
• W2143458171 type Work @default.
• W2143458171 sameAs 2143458171 @default.
• W2143458171 citedByCount "12" @default.
• W2143458171 countsByYear W21434581712016 @default.
• W2143458171 countsByYear W21434581712017 @default.
• W2143458171 countsByYear W21434581712018 @default.
• W2143458171 countsByYear W21434581712019 @default.
• W2143458171 countsByYear W21434581712021 @default.
• W2143458171 countsByYear W21434581712022 @default.
• W2143458171 crossrefType "journal-article" @default.
• W2143458171 hasAuthorship W2143458171A5012173155 @default.
• W2143458171 hasAuthorship W2143458171A5026488520 @default.
• W2143458171 hasAuthorship W2143458171A5046215043 @default.
• W2143458171 hasAuthorship W2143458171A5049272893 @default.
• W2143458171 hasAuthorship W2143458171A5062999838 @default.
• W2143458171 hasAuthorship W2143458171A5064074824 @default.
• W2143458171 hasBestOaLocation W21434581711 @default.
• W2143458171 hasConcept C126322002 @default.
• W2143458171 hasConcept C134018914 @default.
• W2143458171 hasConcept C17093226 @default.
• W2143458171 hasConcept C2776252253 @default.
• W2143458171 hasConcept C2776914184 @default.
• W2143458171 hasConcept C2777391703 @default.
• W2143458171 hasConcept C2778754761 @default.
• W2143458171 hasConcept C40438245 @default.
• W2143458171 hasConcept C511355011 @default.
• W2143458171 hasConcept C555293320 @default.
• W2143458171 hasConcept C71924100 @default.
• W2143458171 hasConceptScore W2143458171C126322002 @default.
• W2143458171 hasConceptScore W2143458171C134018914 @default.
• W2143458171 hasConceptScore W2143458171C17093226 @default.
• W2143458171 hasConceptScore W2143458171C2776252253 @default.
• W2143458171 hasConceptScore W2143458171C2776914184 @default.
• W2143458171 hasConceptScore W2143458171C2777391703 @default.
• W2143458171 hasConceptScore W2143458171C2778754761 @default.

• next