FRINK Linked Data Fragments server

Matches in SemOpenAlex for { <https://semopenalex.org/work/W2147299416> ?p ?o ?g. }

• W2147299416 endingPage "1789" @default.
• W2147299416 startingPage "1779" @default.
• W2147299416 abstract "The conidial germling of Metarhizium anisopliae produces an appressorium upon contact with a hard hydrophobic surface. We have conducted an investigation into how this entomopathogen mediates intracellularly the inductive signal to shift from polarized germ-tube growth to non-polarized appressorial growth. During sporulation, conidia accumulated 45Ca2+ but there was no evidence for a gradient of Ca2+ in the spore which could establish the initial polarity. Calmodulin, however, was localized at the poles of the conidia, near the site of germ-tube emergence. Exposing conidia to Ca2+ deprivation or calmodulin antagonists inhibited germination and polar growth. Disruption of Ca2+ gradients by ionophoresis did not prevent germination but caused the multiple emergence of branched germ-tubes from conidia. These findings indicate that Ca2+ plays a fundamental role in establishing the dominance of apical growth. Although an external source of Ca2+ is not required for appressorium formation, germlings producing appressoria took up 45Ca2+ when available. The 45Ca2+ accumulated in the cell wall, plasma membrane and organelles suggesting that these may function as Ca2+ stores for Ca2+-stimulated exocytosis of cell-wall materials. Mitochondria and vacuoles sequestered 45Ca2+ indicating that they play a role in maintaining low cytoplasmic concentrations of 45Ca2+ consistent with the reorganization of the cytoskeleton required for appressorial growth. Several Ca2+-binding proteins in appressoria may provide an energy-independent component of Ca2+ buffering in the cytoplasm. The results indicate that the apical Ca2+ gradient is disrupted during differentiation and subsequent differential Ca2+ redistribution in the cell enlargement zone coincides with germ-tube swelling. cAMP may also be involved by potentiating the effects of small changes in Ca2+ concentration and stimulating exocytosis of mucus components required for adhesion, which is a prerequisite for differentiation." @default.
• W2147299416 created "2016-06-24" @default.
• W2147299416 creator A5011803370 @default.
• W2147299416 creator A5050058184 @default.
• W2147299416 creator A5055282694 @default.
• W2147299416 creator A5087002918 @default.
• W2147299416 date "1990-09-01" @default.
• W2147299416 modified "2023-09-28" @default.
• W2147299416 title "Second messenger involvement in differentiation of the entomopathogenic fungus Metarhizium anisopliae" @default.
• W2147299416 cites W1026707726 @default.
• W2147299416 cites W1442182549 @default.
• W2147299416 cites W1482693304 @default.
• W2147299416 cites W1485769438 @default.
• W2147299416 cites W1498819956 @default.
• W2147299416 cites W1552337332 @default.
• W2147299416 cites W1825270425 @default.
• W2147299416 cites W1935355922 @default.
• W2147299416 cites W1985284177 @default.
• W2147299416 cites W2005496072 @default.
• W2147299416 cites W2005863627 @default.
• W2147299416 cites W2017555393 @default.
• W2147299416 cites W2020225682 @default.
• W2147299416 cites W2021046132 @default.
• W2147299416 cites W2029674271 @default.
• W2147299416 cites W2032175585 @default.
• W2147299416 cites W2033077000 @default.
• W2147299416 cites W2060556946 @default.
• W2147299416 cites W2064918119 @default.
• W2147299416 cites W2067860985 @default.
• W2147299416 cites W2083652574 @default.
• W2147299416 cites W2088445940 @default.
• W2147299416 cites W2090662531 @default.
• W2147299416 cites W2115275105 @default.
• W2147299416 cites W2128635872 @default.
• W2147299416 cites W2133001309 @default.
• W2147299416 cites W2140000099 @default.
• W2147299416 cites W2140807560 @default.
• W2147299416 cites W2148460267 @default.
• W2147299416 cites W5150485 @default.
• W2147299416 doi "https://doi.org/10.1099/00221287-136-9-1779" @default.
• W2147299416 hasPublicationYear "1990" @default.
• W2147299416 type Work @default.
• W2147299416 sameAs 2147299416 @default.
• W2147299416 citedByCount "39" @default.
• W2147299416 countsByYear W21472994162017 @default.
• W2147299416 countsByYear W21472994162018 @default.
• W2147299416 countsByYear W21472994162020 @default.
• W2147299416 countsByYear W21472994162021 @default.
• W2147299416 countsByYear W21472994162022 @default.
• W2147299416 crossrefType "journal-article" @default.
• W2147299416 hasAuthorship W2147299416A5011803370 @default.
• W2147299416 hasAuthorship W2147299416A5050058184 @default.
• W2147299416 hasAuthorship W2147299416A5055282694 @default.
• W2147299416 hasAuthorship W2147299416A5087002918 @default.
• W2147299416 hasBestOaLocation W21472994161 @default.
• W2147299416 hasConcept C104317684 @default.
• W2147299416 hasConcept C120691718 @default.
• W2147299416 hasConcept C125235067 @default.
• W2147299416 hasConcept C12554922 @default.
• W2147299416 hasConcept C126203033 @default.
• W2147299416 hasConcept C143065580 @default.
• W2147299416 hasConcept C168197293 @default.
• W2147299416 hasConcept C175969161 @default.
• W2147299416 hasConcept C181199279 @default.
• W2147299416 hasConcept C190062978 @default.
• W2147299416 hasConcept C2777407749 @default.
• W2147299416 hasConcept C2779347548 @default.
• W2147299416 hasConcept C2780618852 @default.
• W2147299416 hasConcept C29688787 @default.
• W2147299416 hasConcept C34069715 @default.
• W2147299416 hasConcept C36755584 @default.
• W2147299416 hasConcept C41625074 @default.
• W2147299416 hasConcept C43143990 @default.
• W2147299416 hasConcept C55493867 @default.
• W2147299416 hasConcept C59822182 @default.
• W2147299416 hasConcept C86803240 @default.
• W2147299416 hasConcept C95444343 @default.
• W2147299416 hasConceptScore W2147299416C104317684 @default.
• W2147299416 hasConceptScore W2147299416C120691718 @default.
• W2147299416 hasConceptScore W2147299416C125235067 @default.
• W2147299416 hasConceptScore W2147299416C12554922 @default.
• W2147299416 hasConceptScore W2147299416C126203033 @default.
• W2147299416 hasConceptScore W2147299416C143065580 @default.
• W2147299416 hasConceptScore W2147299416C168197293 @default.
• W2147299416 hasConceptScore W2147299416C175969161 @default.
• W2147299416 hasConceptScore W2147299416C181199279 @default.
• W2147299416 hasConceptScore W2147299416C190062978 @default.
• W2147299416 hasConceptScore W2147299416C2777407749 @default.
• W2147299416 hasConceptScore W2147299416C2779347548 @default.
• W2147299416 hasConceptScore W2147299416C2780618852 @default.
• W2147299416 hasConceptScore W2147299416C29688787 @default.
• W2147299416 hasConceptScore W2147299416C34069715 @default.
• W2147299416 hasConceptScore W2147299416C36755584 @default.
• W2147299416 hasConceptScore W2147299416C41625074 @default.
• W2147299416 hasConceptScore W2147299416C43143990 @default.
• W2147299416 hasConceptScore W2147299416C55493867 @default.
• W2147299416 hasConceptScore W2147299416C59822182 @default.
• W2147299416 hasConceptScore W2147299416C86803240 @default.

• next