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- W2152765281 abstract "Editor's Capsule Summary for Stiell et al1Stiell I. Clement C.M. Brison R.J. et al.Variation in management of recent-onset atrial fibrillation and flutter among academic hospital emergency departments.Ann Emerg Med. 2011; 57: 13-21Abstract Full Text Full Text PDF PubMed Scopus (99) Google ScholarWhat is already known on this topic: There is controversy about whether rhythm or rate control should be the primary goal of emergency department (ED) management of atrial fibrillation and flutter.What question this study addressed: What variation exists in the care of ED patients with rapid atrial fibrillation or flutter?What this study adds to our knowledge: In chart review of 1,068 patients in 8 academic Canadian hospitals, 88% had atrial fibrillation and 12% flutter. Rhythm control was attempted in 60% of patients; electrocardioversion, in 44%. Eighty three percent of patients were discharged home. There was considerable variation among sites.How this is relevant to clinical practice: These 8 hospitals use different strategies, all of which seem safe. The optimal practice has not been defined. What is already known on this topic: There is controversy about whether rhythm or rate control should be the primary goal of emergency department (ED) management of atrial fibrillation and flutter. What question this study addressed: What variation exists in the care of ED patients with rapid atrial fibrillation or flutter? What this study adds to our knowledge: In chart review of 1,068 patients in 8 academic Canadian hospitals, 88% had atrial fibrillation and 12% flutter. Rhythm control was attempted in 60% of patients; electrocardioversion, in 44%. Eighty three percent of patients were discharged home. There was considerable variation among sites. How this is relevant to clinical practice: These 8 hospitals use different strategies, all of which seem safe. The optimal practice has not been defined. 1Stiell et al1Stiell I. Clement C.M. Brison R.J. et al.Variation in management of recent-onset atrial fibrillation and flutter among academic hospital emergency departments.Ann Emerg Med. 2011; 57: 13-21Abstract Full Text Full Text PDF PubMed Scopus (99) Google Scholar hypothesize that treatment of recent-onset atrial fibrillation/flutter will vary substantially from hospital to hospital.AWhat reasons do the authors give for generating this hypothesis? Do you agree with their reasoning?BConsider the matrix below, which contrasts the medical evidence in support of a specific process of care with the variation in practice for that condition. Can you think of medical conditions that fall into each of the boxes? Into which box (A, B, C, and D) does the management of acute atrial fibrillation fall? Discuss the arguments for and against a practice pattern that falls into each box.Tabled 1Variability of CareLowHighEvidence supporting a specific strategyLowABHighCD Open table in a new tab CIs variation always a bad thing? Is standardization always a good thing? In 2010, how much variation is desirable for the management of acute-onset atrial fibrillation?2This article seeks to explain variation at the hospital level.AWhat is the inherent structure of the data used in this study? Who determines each patient's treatment? What N is used for this study? What are the possible Ns for this study? Make an argument for and against each unit of analysis that you identify.BAn alternative analysis of these data would involve a multilevel model with patients nested within physicians and physicians nested within hospitals. One could then compare the variation in practice among the physicians at each site with the variation in practice among sites. Do you think this is worth doing? Sketch out what (extreme) results are possible and what result you would expect to find.CImagine you found that between-hospital variation exceeded inter-physician variation. What does that say about the practice of emergency medicine? What implications does it have for methods of changing practice?DThe regression models used in this study treat the patient as the unit of analysis, predicting whether a particular patient will be rhythm or rate controlled according to the patient's demographic and clinical characteristics and the emergency department (ED) providing treatment. The investigators used backward stepwise regression on a pool of 12 patient-level clinical variables selected because they would adjust hospital effects for case mix. Explain how this model is supposed to work and how it should be interpreted. Discuss any problems with the methods of model specification, selection of candidate variables, and variable selection. Can you describe how alternative models such as one that sought to predict hospital rhythm/rate control proportions from patient, physician, and hospital characteristics might work?3Roughly 60% of patients were treated with rhythm control, implying that the majority of physicians at these 8 hospitals thought that a return to sinus rhythm was in the best interest of the patients included in this study.AWhat is the evidence about rate versus rhythm control for ED patients with acute-onset atrial fibrillation?BIf a patient in atrial fibrillation is converted to sinus rhythm, what are the chances that the patient will return to atrial fibrillation/flutter in the next few months? If a patient is rate controlled and remains in atrial fibrillation/flutter, what is the short-term risk of atrial clot formation? What is the short-term risk of thromboembolic sequelae? If a patient is chemically or electrically cardioverted to sinus rhythm, what is the short-term risk of atrial thrombus formation or thromboembolic sequelae?CWhat outcomes are of interest when comparing rate control with rhythm control? What are the ideal times to measure such outcomes? How does your list compare with those reported in Table 3 of the article by Stiell et al?1Stiell I. Clement C.M. Brison R.J. et al.Variation in management of recent-onset atrial fibrillation and flutter among academic hospital emergency departments.Ann Emerg Med. 2011; 57: 13-21Abstract Full Text Full Text PDF PubMed Scopus (99) Google ScholarDWhat types of studies would help you determine the preferred strategy? Do those studies exist? If not, why not?4The 8 Canadian hospitals discharged 83% of study subjects from the ED (range 74% to 95%). In this same issue of Annals, Barrett et al2Barrett T.W. Martin A.R. Storrow A.B. et al.A clinical prediction model to estimate risk for 30-day adverse events in emergency department patients with symptomatic atrial fibrillation.Ann Emerg Med. 2011; 57: 1-12Abstract Full Text Full Text PDF PubMed Scopus (46) Google Scholar reported that at a large US academic teaching hospital, only 23% of similar patients were discharged.AWhat could account for such a dramatic difference in practice style? Are there any characteristics of the sites that would account for the difference?BAre there any other medical conditions for which the discharge rates between the 2 countries diverge so dramatically? Compared with other parts of the first world whose practice is aberrant, the United States or Canada?CCan you think of a reason why patients who have achieved rhythm or rate control in the ED might still benefit from hospital admission?DIf you were in charge of a nationwide health care system, what strategy would you select and why? What information would be most helpful in making such a decision? Variation in Management of Recent-Onset Atrial Fibrillation and Flutter Among Academic Hospital Emergency DepartmentsAnnals of Emergency MedicineVol. 57Issue 1PreviewAlthough recent-onset atrial fibrillation and flutter are common arrhythmias managed in the emergency department (ED), there is insufficient evidence to help physicians choose between 2 competing treatment strategies, rate control and rhythm control. We seek to evaluate variation in ED management practices for recent-onset atrial fibrillation and flutter patients at multiple Canadian sites and to determine whether hospital site was an independent predictor of attempted cardioversion. Full-Text PDF" @default.
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- W2152765281 title "To Shock or Not to Shock: That is the Question; is There an Answer?" @default.
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