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• W2153224441 abstract "Arsenic in drinking water is a public health issue affecting hundreds of millions of people worldwide. This review summarizes 30 years of epidemiological studies on arsenic exposure in drinking water and the risk of bladder or kidney cancer, quantifying these risks using a meta-analytical framework.Forty studies met the selection criteria. Seventeen provided point estimates of arsenic concentrations in drinking water and were used in a meta-analysis of bladder cancer incidence (7 studies) and mortality (10 studies) and kidney cancer mortality (2 studies). Risk estimates for incidence and mortality were analyzed separately using Generalized Linear Models. Predicted risks for bladder cancer incidence were estimated at 10, 50 and 150 μg/L arsenic in drinking water. Bootstrap randomizations were used to assess robustness of effect size.Twenty-eight studies observed an association between arsenic in drinking water and bladder cancer. Ten studies showed an association with kidney cancer, although of lower magnitude than that for bladder cancer. The meta-analyses showed the predicted risks for bladder cancer incidence were 2.7 [1.2-4.1]; 4.2 [2.1-6.3] and; 5.8 [2.9-8.7] for drinking water arsenic levels of 10, 50, and 150 μg/L, respectively. Bootstrapped randomizations confirmed this increased risk, but, lowering the effect size to 1.4 [0.35-4.0], 2.3 [0.59-6.4], and 3.1 [0.80-8.9]. The latter suggests that with exposures to 50 μg/L, there was an 83% probability for elevated incidence of bladder cancer; and a 74% probability for elevated mortality. For both bladder and kidney cancers, mortality rates at 150 ug/L were about 30% greater than those at 10 μg/L.Arsenic in drinking water is associated with an increased risk of bladder and kidney cancers, although at lower levels (<150 μg/L), there is uncertainty due to the increased likelihood of exposure misclassification at the lower end of the exposure curve. Meta-analyses suggest exposure to 10 μg/L of arsenic in drinking water may double the risk of bladder cancer, or at the very least, increase it by about 40%. With the large number of people exposed to these arsenic concentrations worldwide the public health consequences of arsenic in drinking water are substantial." @default.
• W2153224441 created "2016-06-24" @default.
• W2153224441 creator A5006057377 @default.
• W2153224441 creator A5028491591 @default.
• W2153224441 creator A5042275901 @default.
• W2153224441 creator A5090431349 @default.
• W2153224441 date "2014-06-02" @default.
• W2153224441 modified "2023-10-14" @default.
• W2153224441 title "Arsenic in drinking water and urinary tract cancers: a systematic review of 30 years of epidemiological evidence" @default.
• W2153224441 cites W1742821047 @default.
• W2153224441 cites W1933843339 @default.
• W2153224441 cites W1968332157 @default.
• W2153224441 cites W1979423827 @default.
• W2153224441 cites W1985869400 @default.
• W2153224441 cites W1988033013 @default.
• W2153224441 cites W1990452086 @default.
• W2153224441 cites W1992287564 @default.
• W2153224441 cites W1993338946 @default.
• W2153224441 cites W1995338674 @default.
• W2153224441 cites W1995945562 @default.
• W2153224441 cites W1997363805 @default.
• W2153224441 cites W2008165764 @default.
• W2153224441 cites W2008561036 @default.
• W2153224441 cites W2009046453 @default.
• W2153224441 cites W2009317934 @default.
• W2153224441 cites W2011388076 @default.
• W2153224441 cites W2013505014 @default.
• W2153224441 cites W2014542201 @default.
• W2153224441 cites W2017443746 @default.
• W2153224441 cites W2019486900 @default.
• W2153224441 cites W2020532113 @default.
• W2153224441 cites W2020543638 @default.
• W2153224441 cites W2022320538 @default.
• W2153224441 cites W2026646794 @default.
• W2153224441 cites W2026920894 @default.
• W2153224441 cites W2031593345 @default.
• W2153224441 cites W2035029439 @default.
• W2153224441 cites W2035310883 @default.
• W2153224441 cites W2035434404 @default.
• W2153224441 cites W2036281005 @default.
• W2153224441 cites W2039716376 @default.
• W2153224441 cites W2043873488 @default.
• W2153224441 cites W2046210218 @default.
• W2153224441 cites W2046471358 @default.
• W2153224441 cites W2048068440 @default.
• W2153224441 cites W2048874346 @default.
• W2153224441 cites W2050608967 @default.
• W2153224441 cites W2055523016 @default.
• W2153224441 cites W2059949476 @default.
• W2153224441 cites W2061159442 @default.
• W2153224441 cites W2061739529 @default.
• W2153224441 cites W2063754654 @default.
• W2153224441 cites W2064844197 @default.
• W2153224441 cites W2067345545 @default.
• W2153224441 cites W2070357590 @default.
• W2153224441 cites W2072110196 @default.
• W2153224441 cites W2072763085 @default.
• W2153224441 cites W2077007063 @default.
• W2153224441 cites W2078011109 @default.
• W2153224441 cites W2080379480 @default.
• W2153224441 cites W2086720782 @default.
• W2153224441 cites W2089365131 @default.
• W2153224441 cites W2096860860 @default.
• W2153224441 cites W2098893517 @default.
• W2153224441 cites W2102311939 @default.
• W2153224441 cites W2104421773 @default.
• W2153224441 cites W2105897307 @default.
• W2153224441 cites W2107462675 @default.
• W2153224441 cites W2109732829 @default.
• W2153224441 cites W2110244716 @default.
• W2153224441 cites W2110266722 @default.
• W2153224441 cites W2117705442 @default.
• W2153224441 cites W2121754812 @default.
• W2153224441 cites W2122146045 @default.
• W2153224441 cites W2126067437 @default.
• W2153224441 cites W2126474123 @default.
• W2153224441 cites W2131439409 @default.
• W2153224441 cites W2133051107 @default.
• W2153224441 cites W2137052778 @default.
• W2153224441 cites W2137168194 @default.
• W2153224441 cites W2137481251 @default.
• W2153224441 cites W2140056228 @default.
• W2153224441 cites W2140121626 @default.
• W2153224441 cites W2140623642 @default.
• W2153224441 cites W2144830297 @default.
• W2153224441 cites W2145062382 @default.
• W2153224441 cites W2146053741 @default.
• W2153224441 cites W2149602337 @default.
• W2153224441 cites W2151681632 @default.
• W2153224441 cites W2153393969 @default.
• W2153224441 cites W2158866283 @default.
• W2153224441 cites W2160057478 @default.
• W2153224441 cites W2163964558 @default.
• W2153224441 cites W2164569497 @default.
• W2153224441 cites W2172219600 @default.
• W2153224441 cites W2219880628 @default.
• W2153224441 cites W2327281344 @default.
• W2153224441 cites W4211223486 @default.
• W2153224441 cites W4246748514 @default.
• W2153224441 doi "https://doi.org/10.1186/1476-069x-13-44" @default.

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