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• W2155299288 abstract "The cellular prion protein (PrP c ) is a highly conserved glycoprotein with a still enigmatic physiological function. It is mainly expressed in the central nervous system but accumulating data suggest that PrP c is also found in a broad spectrum of non-neuronal tissue. Here we investigated the cell-type-related PrP c expression in the bovine mammary gland by using immunohistochemistry (IHC), ELISA, Western blot, and real-time RT-PCR. Specific immunostaining of serial sections revealed that PrP c is selectively localized in mammary gland epithelial cells. Particularly strong expression was found at the basolateral surface of those cells showing active secretion. Results obtained by RT-PCR and ELISA complemented IHC findings. No correlation was found between the level of PrP c expression and other parameters such as age of the animals under study or stage of lactation." @default.
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• W2155299288 date "2006-07-24" @default.
• W2155299288 modified "2023-10-12" @default.
• W2155299288 title "Cellular Prion Protein in the Bovine Mammary Gland Is Selectively Expressed in Active Lactocytes" @default.
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• W2155299288 doi "https://doi.org/10.1369/jhc.5a6880.2006" @default.
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