FRINK Linked Data Fragments server

Matches in SemOpenAlex for { <https://semopenalex.org/work/W2156773815> ?p ?o ?g. }

• W2156773815 endingPage "74" @default.
• W2156773815 startingPage "466" @default.
• W2156773815 abstract "Congenital mild bleeding disorders (MBDs) are very prevalent and are the source of frequent diagnostic problems. Most MBDs are categorized as disorders of primary hemostasis (ie, type 1 VWD and platelet function disorders), but mild or moderate deficiencies of clotting factors and some rare hyperfibrinolytic disorders are also included. These patients have abnormal bleeding from the skin and mucous membranes, menorrhagia, and disproportionate hemorrhages after trauma, invasive procedures, and surgery. This review addresses the main problems that physicians and hemostasis laboratories confront with the diagnosis of these patients, including: discerning normal/appropriate from pathological bleeding, the role and yield of screening tests, the lack of distinctive bleeding pattern among the different diseases, the inherent difficulties in the diagnosis of type 1 VWD and the most common platelet functional disorders, improvements in assays to measure platelet aggregation and secretion, and the evidence that most of the patients with MBDs end up without a definite diagnosis after exhaustive and repeated laboratory testing. Much research is needed to determine the pathogenesis of bleeding in MBD patients. Better standardization of current laboratory assays, progress in the knowledge of fibrinolytic mechanisms and their laboratory evaluation, and new understanding of the factors contributing to platelet-vessel wall interaction, along with the corresponding development of laboratory tools, should improve our capacity to diagnose a greater proportion of patients with MBDs." @default.
• W2156773815 created "2016-06-24" @default.
• W2156773815 creator A5055869476 @default.
• W2156773815 creator A5068326719 @default.
• W2156773815 date "2012-01-01" @default.
• W2156773815 modified "2023-09-29" @default.
• W2156773815 title "Is my patient a bleeder? A diagnostic framework for mild bleeding disorders." @default.
• W2156773815 cites W125565931 @default.
• W2156773815 cites W1493000949 @default.
• W2156773815 cites W1495374819 @default.
• W2156773815 cites W1496174784 @default.
• W2156773815 cites W1504530782 @default.
• W2156773815 cites W1505239733 @default.
• W2156773815 cites W1514976055 @default.
• W2156773815 cites W1547206336 @default.
• W2156773815 cites W1559380682 @default.
• W2156773815 cites W1636726289 @default.
• W2156773815 cites W1780927501 @default.
• W2156773815 cites W190014962 @default.
• W2156773815 cites W190408506 @default.
• W2156773815 cites W1965653365 @default.
• W2156773815 cites W1966951431 @default.
• W2156773815 cites W1967103038 @default.
• W2156773815 cites W1967933685 @default.
• W2156773815 cites W1968058606 @default.
• W2156773815 cites W1985600246 @default.
• W2156773815 cites W1988769064 @default.
• W2156773815 cites W1998543407 @default.
• W2156773815 cites W1998838483 @default.
• W2156773815 cites W2001998234 @default.
• W2156773815 cites W2006760464 @default.
• W2156773815 cites W2012880961 @default.
• W2156773815 cites W2023211628 @default.
• W2156773815 cites W2025124948 @default.
• W2156773815 cites W2028138842 @default.
• W2156773815 cites W2031994999 @default.
• W2156773815 cites W2034485327 @default.
• W2156773815 cites W2045180012 @default.
• W2156773815 cites W2050360907 @default.
• W2156773815 cites W2055284800 @default.
• W2156773815 cites W2057338534 @default.
• W2156773815 cites W2062511047 @default.
• W2156773815 cites W2063944144 @default.
• W2156773815 cites W2064616188 @default.
• W2156773815 cites W2065359526 @default.
• W2156773815 cites W2069539892 @default.
• W2156773815 cites W2075493428 @default.
• W2156773815 cites W2081708670 @default.
• W2156773815 cites W2084006614 @default.
• W2156773815 cites W2087235653 @default.
• W2156773815 cites W2091826825 @default.
• W2156773815 cites W2107007076 @default.
• W2156773815 cites W2125061752 @default.
• W2156773815 cites W2127341416 @default.
• W2156773815 cites W2129207263 @default.
• W2156773815 cites W2139323943 @default.
• W2156773815 cites W2141377159 @default.
• W2156773815 cites W2155624681 @default.
• W2156773815 cites W2168627661 @default.
• W2156773815 cites W2169344158 @default.
• W2156773815 cites W2169541709 @default.
• W2156773815 cites W2171630863 @default.
• W2156773815 cites W2237621368 @default.
• W2156773815 cites W2248050368 @default.
• W2156773815 cites W2283135561 @default.
• W2156773815 cites W2341426834 @default.
• W2156773815 cites W2412230954 @default.
• W2156773815 cites W2419509020 @default.
• W2156773815 cites W2808348123 @default.
• W2156773815 cites W3021235715 @default.
• W2156773815 cites W32427409 @default.
• W2156773815 cites W3150169764 @default.
• W2156773815 doi "https://doi.org/10.1182/asheducation-2012.1.466" @default.
• W2156773815 hasPubMedId "https://pubmed.ncbi.nlm.nih.gov/23233621" @default.
• W2156773815 hasPublicationYear "2012" @default.
• W2156773815 type Work @default.
• W2156773815 sameAs 2156773815 @default.
• W2156773815 citedByCount "22" @default.
• W2156773815 countsByYear W21567738152014 @default.
• W2156773815 countsByYear W21567738152016 @default.
• W2156773815 countsByYear W21567738152017 @default.
• W2156773815 countsByYear W21567738152018 @default.
• W2156773815 countsByYear W21567738152019 @default.
• W2156773815 countsByYear W21567738152021 @default.
• W2156773815 countsByYear W21567738152022 @default.
• W2156773815 countsByYear W21567738152023 @default.
• W2156773815 crossrefType "journal-article" @default.
• W2156773815 hasAuthorship W2156773815A5055869476 @default.
• W2156773815 hasAuthorship W2156773815A5068326719 @default.
• W2156773815 hasConcept C126322002 @default.
• W2156773815 hasConcept C141071460 @default.
• W2156773815 hasConcept C142724271 @default.
• W2156773815 hasConcept C177713679 @default.
• W2156773815 hasConcept C207886595 @default.
• W2156773815 hasConcept C2778589496 @default.
• W2156773815 hasConcept C2910090564 @default.
• W2156773815 hasConcept C71924100 @default.
• W2156773815 hasConcept C89560881 @default.

• next