Matches in SemOpenAlex for { <https://semopenalex.org/work/W2176948581> ?p ?o ?g. }
Showing items 1 to 90 of
90
with 100 items per page.
- W2176948581 abstract "Many pathologies are associated with abnormalities of glucose metabolism or with perturbations of its transport (type 2 diabetes or insulin-resistance). The pre-diabetic state is characterised by a state of insulin-resistance, in others words a defect of glucose transport in insulin-sensible tissues, such as muscles and adipose tissues. The mathematical modelling of experimental data can be an excellent method to explore the mechanisms implied in the studied biological phenomenon. Thus, starting from a symbolic formulation like the compartmental modelling, it can be possible to develop a theoretical basis for the observation and to consider the best-adapted experiments for the study. We showed with mathematical models that [123I]-6-deoxy-6-iodo-D-glucose (6-DIG), shown as a tracer of glucose transport in vitro, could point out this transport abnormality. To quantify the insulin resistance, we estimated the fractional transfer coefficients of 6-DIG from the blood to the organs. We realised many studies to lead to a satisfying model; special attention has been paid to the precision of the parameter to select the best model. The results showed that by associating experimental data obtained with 6-DIG activities and an adapted mathematical model, discriminating parameters (in and out fractional transfer coefficients) between the two groups (control and insulin-resistant rats) could be pointed out." @default.
- W2176948581 created "2016-06-24" @default.
- W2176948581 creator A5025140010 @default.
- W2176948581 creator A5033871371 @default.
- W2176948581 creator A5040800580 @default.
- W2176948581 creator A5059384131 @default.
- W2176948581 creator A5061833491 @default.
- W2176948581 creator A5062221519 @default.
- W2176948581 creator A5074747542 @default.
- W2176948581 date "2002-04-01" @default.
- W2176948581 modified "2023-09-27" @default.
- W2176948581 title "Modélisation multicompartimentale et stratégies expérimentales pour l’étude du transport du glucose chez le rat insulinorésistant" @default.
- W2176948581 cites W1499875090 @default.
- W2176948581 cites W1881146567 @default.
- W2176948581 cites W1907993061 @default.
- W2176948581 cites W193931337 @default.
- W2176948581 cites W1969052161 @default.
- W2176948581 cites W1973095532 @default.
- W2176948581 cites W2001804635 @default.
- W2176948581 cites W2013603470 @default.
- W2176948581 cites W2018420784 @default.
- W2176948581 cites W2020830596 @default.
- W2176948581 cites W2037211078 @default.
- W2176948581 cites W2043353232 @default.
- W2176948581 cites W2048164553 @default.
- W2176948581 cites W2060591324 @default.
- W2176948581 cites W2087823410 @default.
- W2176948581 cites W2105912552 @default.
- W2176948581 cites W2111284664 @default.
- W2176948581 cites W2118976195 @default.
- W2176948581 cites W2129730142 @default.
- W2176948581 cites W2145238247 @default.
- W2176948581 cites W2146877877 @default.
- W2176948581 cites W2184337525 @default.
- W2176948581 cites W2184444245 @default.
- W2176948581 cites W2281243857 @default.
- W2176948581 cites W2294613746 @default.
- W2176948581 cites W2297517887 @default.
- W2176948581 cites W2987025408 @default.
- W2176948581 cites W337435557 @default.
- W2176948581 cites W392722801 @default.
- W2176948581 cites W77873670 @default.
- W2176948581 cites W95031257 @default.
- W2176948581 cites W2487296601 @default.
- W2176948581 doi "https://doi.org/10.1016/s1631-0691(02)01455-5" @default.
- W2176948581 hasPubMedId "https://pubmed.ncbi.nlm.nih.gov/12161932" @default.
- W2176948581 hasPublicationYear "2002" @default.
- W2176948581 type Work @default.
- W2176948581 sameAs 2176948581 @default.
- W2176948581 citedByCount "2" @default.
- W2176948581 countsByYear W21769485812017 @default.
- W2176948581 crossrefType "journal-article" @default.
- W2176948581 hasAuthorship W2176948581A5025140010 @default.
- W2176948581 hasAuthorship W2176948581A5033871371 @default.
- W2176948581 hasAuthorship W2176948581A5040800580 @default.
- W2176948581 hasAuthorship W2176948581A5059384131 @default.
- W2176948581 hasAuthorship W2176948581A5061833491 @default.
- W2176948581 hasAuthorship W2176948581A5062221519 @default.
- W2176948581 hasAuthorship W2176948581A5074747542 @default.
- W2176948581 hasConcept C134018914 @default.
- W2176948581 hasConcept C161573976 @default.
- W2176948581 hasConcept C185592680 @default.
- W2176948581 hasConcept C2777391703 @default.
- W2176948581 hasConcept C2779306644 @default.
- W2176948581 hasConcept C86803240 @default.
- W2176948581 hasConceptScore W2176948581C134018914 @default.
- W2176948581 hasConceptScore W2176948581C161573976 @default.
- W2176948581 hasConceptScore W2176948581C185592680 @default.
- W2176948581 hasConceptScore W2176948581C2777391703 @default.
- W2176948581 hasConceptScore W2176948581C2779306644 @default.
- W2176948581 hasConceptScore W2176948581C86803240 @default.
- W2176948581 hasLocation W21769485811 @default.
- W2176948581 hasLocation W21769485812 @default.
- W2176948581 hasLocation W21769485813 @default.
- W2176948581 hasOpenAccess W2176948581 @default.
- W2176948581 hasPrimaryLocation W21769485811 @default.
- W2176948581 hasRelatedWork W2003112034 @default.
- W2176948581 hasRelatedWork W2089400978 @default.
- W2176948581 hasRelatedWork W2099789512 @default.
- W2176948581 hasRelatedWork W2106310612 @default.
- W2176948581 hasRelatedWork W2191605427 @default.
- W2176948581 hasRelatedWork W2341781836 @default.
- W2176948581 hasRelatedWork W2438462969 @default.
- W2176948581 hasRelatedWork W2969979995 @default.
- W2176948581 hasRelatedWork W3118045786 @default.
- W2176948581 hasRelatedWork W63976403 @default.
- W2176948581 isParatext "false" @default.
- W2176948581 isRetracted "false" @default.
- W2176948581 magId "2176948581" @default.
- W2176948581 workType "article" @default.