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- W2185953612 abstract "The analysis of neurotransmitter in single cell level is essential because drug screening of many fatal neuronal diseases can be discovered. However, current biological experimental methods have difficulty to increase the throughput of drug screening due to lack of sophisticated fluidic control or cell handling. In order to provide an effective experimental tool for the analysis of neurotransmitter release, we developed a microfluidic device for sniffer patch assay using selective trapping of cell-pairs. Two different cells were positioned using an array of trapping channels with a cross-section of 3 μm by 2 μm. It was designed to be compatible with conventional sniffer patch assay setup. We could verify that the operation of the device and we could obtain comparable result about Ca" @default.
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- W2185953612 date "2010-01-01" @default.
- W2185953612 modified "2023-09-27" @default.
- W2185953612 title "'SNIFFER-PATCH ASSAY' ON A MICROFLUIDIC CHIP FOR HIGH-THROUGHPUT SCREENING OF DRUGS TO CONTROL NEUROTRANSMITTER RELEASE" @default.
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