Matches in SemOpenAlex for { <https://semopenalex.org/work/W2316968435> ?p ?o ?g. }
Showing items 1 to 66 of
66
with 100 items per page.
- W2316968435 endingPage "50" @default.
- W2316968435 startingPage "48" @default.
- W2316968435 abstract "Salicylate at 5 mM inhibited ureagenesis from NH4C1 by about 45% in rat liver slices. Salicylate also inhibited ci-trulline synthesis in isolated mitochondria. It had no direct effect on carbamyl phosphate synthetase or ornithine transcarba-mylase assayed in liver homogenates. Salicylate did not inhibit citrulline synthesis supported by exogenous ATP. Salicylate lowered the carbamyl phosphate concentration in mitochondria incubated without ornithine to minimize citrulline synthesis. Unexpectedly salicylate stimulated mitochondrial ornithine uptake. The inhibition of ureagenesis is probably due to the uncoupling of oxidative phosphorylation which depletes mitochondrial ATP which in turn impairs carbamyl phosphate synthesis." @default.
- W2316968435 created "2016-06-24" @default.
- W2316968435 creator A5025499168 @default.
- W2316968435 creator A5080270536 @default.
- W2316968435 date "1977-05-01" @default.
- W2316968435 modified "2023-09-23" @default.
- W2316968435 title "Effect of Salicylate on Ureagenesis in Rat Liver" @default.
- W2316968435 doi "https://doi.org/10.3181/00379727-155-39742" @default.
- W2316968435 hasPubMedId "https://pubmed.ncbi.nlm.nih.gov/193125" @default.
- W2316968435 hasPublicationYear "1977" @default.
- W2316968435 type Work @default.
- W2316968435 sameAs 2316968435 @default.
- W2316968435 citedByCount "6" @default.
- W2316968435 crossrefType "journal-article" @default.
- W2316968435 hasAuthorship W2316968435A5025499168 @default.
- W2316968435 hasAuthorship W2316968435A5080270536 @default.
- W2316968435 hasConcept C181199279 @default.
- W2316968435 hasConcept C185592680 @default.
- W2316968435 hasConcept C2776796294 @default.
- W2316968435 hasConcept C2777132085 @default.
- W2316968435 hasConcept C2777468819 @default.
- W2316968435 hasConcept C2779129087 @default.
- W2316968435 hasConcept C28859421 @default.
- W2316968435 hasConcept C2908748535 @default.
- W2316968435 hasConcept C515207424 @default.
- W2316968435 hasConcept C55493867 @default.
- W2316968435 hasConcept C57600042 @default.
- W2316968435 hasConcept C74539022 @default.
- W2316968435 hasConcept C77061444 @default.
- W2316968435 hasConcept C86803240 @default.
- W2316968435 hasConceptScore W2316968435C181199279 @default.
- W2316968435 hasConceptScore W2316968435C185592680 @default.
- W2316968435 hasConceptScore W2316968435C2776796294 @default.
- W2316968435 hasConceptScore W2316968435C2777132085 @default.
- W2316968435 hasConceptScore W2316968435C2777468819 @default.
- W2316968435 hasConceptScore W2316968435C2779129087 @default.
- W2316968435 hasConceptScore W2316968435C28859421 @default.
- W2316968435 hasConceptScore W2316968435C2908748535 @default.
- W2316968435 hasConceptScore W2316968435C515207424 @default.
- W2316968435 hasConceptScore W2316968435C55493867 @default.
- W2316968435 hasConceptScore W2316968435C57600042 @default.
- W2316968435 hasConceptScore W2316968435C74539022 @default.
- W2316968435 hasConceptScore W2316968435C77061444 @default.
- W2316968435 hasConceptScore W2316968435C86803240 @default.
- W2316968435 hasIssue "1" @default.
- W2316968435 hasLocation W23169684351 @default.
- W2316968435 hasLocation W23169684352 @default.
- W2316968435 hasOpenAccess W2316968435 @default.
- W2316968435 hasPrimaryLocation W23169684351 @default.
- W2316968435 hasRelatedWork W1508846714 @default.
- W2316968435 hasRelatedWork W1519974564 @default.
- W2316968435 hasRelatedWork W1793818529 @default.
- W2316968435 hasRelatedWork W1992799607 @default.
- W2316968435 hasRelatedWork W2003338461 @default.
- W2316968435 hasRelatedWork W2031442399 @default.
- W2316968435 hasRelatedWork W2074793594 @default.
- W2316968435 hasRelatedWork W2076689788 @default.
- W2316968435 hasRelatedWork W2111138113 @default.
- W2316968435 hasRelatedWork W2111513778 @default.
- W2316968435 hasVolume "155" @default.
- W2316968435 isParatext "false" @default.
- W2316968435 isRetracted "false" @default.
- W2316968435 magId "2316968435" @default.
- W2316968435 workType "article" @default.