FRINK Linked Data Fragments server

Matches in SemOpenAlex for { <https://semopenalex.org/work/W2320549531> ?p ?o ?g. }

• W2320549531 abstract "Measuring and monitoring health outcomes is of utmost importance in rheumatology and in medicine in general. Yet quantifying health outcomes, such as disease activity, physical function and health related quality of life, is a complex and challenging process. Composite scores can be particularly useful in measuring health outcomes because they integrate several different aspects of the same outcome into one single numerical value, resulting in a more precise estimate of the outcome than the individual components of the composite score. They also have the potential to increase the statistical power of clinical trials and observational studies. Furthermore, they improve the consistency of patient care across different clinical settings and help patients and doctors better understand the disease and its impact. This does not dispute the fact that there may be times when single construct measures are more appropriate for judging a specific outcome, because the intervention is directed primarily at one construct and not necessarily to produce a more global health change. The OMERACT (Outcome Measures in Rheumatology) has served a critical role in the development and validation of outcome measures in rheumatology (http://www.omeract.org/). The OMERACT filter (Boers et al. J Rheumatol. 1998 Feb;25(2):198-9) is a set of criteria that can serve as guide to develop valid and meaningful indices: 1) Truth: Is the measure truthful, does it measure what it intends to measure? Is the result unbiased and relevant? This criterion captures the issues of face, content, construct and criterion validity. 2) Discrimination: Does the measure discriminate between situations that are of interest? The situations can be states at one time (for classification or prognosis) or states at different times (to measure change). This criterion captures the issues of reliability and sensitivity to change/responsiveness. Feasibility: Can the measure be applied easily, given constraints of time, money, and interpretability? This criterion addresses the pragmatic reality of the use of the measure, one that may be decisive in determining a measure9s success. Regarding the ability to detect change there are two levels at which it can be evaluated: 1) at the level of statistical significance and 2) at the level of clinical meaningfulness. The first level relates to the concept of “minimal detectable change” (the smallest change detectable between two time points) while the second level relates to the concept of “clinically important change” (the smallest change, which individuals experience, that can be considered important or clinically meaningful). Knowing if the amount of change in an index is clinically meaningful is essential to provide adequate patient care. The Ankylosing Spondylitis Disease Activity Score (ASDAS) is a new ASAS (Assessment of SpondyloArthritis international Society) and OMERACT-endorsed composite disease activity index developed for axial Spondyloarthritis (Machado et al. Ann Rheum Dis. 2011 Jan;70(1):47-53). Using the ASDAS as a model, this presentation will discuss the approach to the development of valid and meaningful indices to assess health outcomes in rheumatology. Disclosure of Interest None declared DOI 10.1136/annrheumdis-2014-eular.6289" @default.
• W2320549531 created "2016-06-24" @default.
• W2320549531 creator A5077451505 @default.
• W2320549531 date "2014-06-01" @default.
• W2320549531 modified "2023-09-23" @default.
• W2320549531 title "SP0067 How to Develop Meaningful Indices from Scratch (E.G. ASDAS)" @default.
• W2320549531 doi "https://doi.org/10.1136/annrheumdis-2014-eular.6289" @default.
• W2320549531 hasPublicationYear "2014" @default.
• W2320549531 type Work @default.
• W2320549531 sameAs 2320549531 @default.
• W2320549531 citedByCount "0" @default.
• W2320549531 crossrefType "journal-article" @default.
• W2320549531 hasAuthorship W2320549531A5077451505 @default.
• W2320549531 hasConcept C126322002 @default.
• W2320549531 hasConcept C144237770 @default.
• W2320549531 hasConcept C148220186 @default.
• W2320549531 hasConcept C154945302 @default.
• W2320549531 hasConcept C159110408 @default.
• W2320549531 hasConcept C160735492 @default.
• W2320549531 hasConcept C162324750 @default.
• W2320549531 hasConcept C171606756 @default.
• W2320549531 hasConcept C177264268 @default.
• W2320549531 hasConcept C1862650 @default.
• W2320549531 hasConcept C198451711 @default.
• W2320549531 hasConcept C199360897 @default.
• W2320549531 hasConcept C23131810 @default.
• W2320549531 hasConcept C2776436953 @default.
• W2320549531 hasConcept C2779951463 @default.
• W2320549531 hasConcept C2780801425 @default.
• W2320549531 hasConcept C33191230 @default.
• W2320549531 hasConcept C33923547 @default.
• W2320549531 hasConcept C41008148 @default.
• W2320549531 hasConcept C49453240 @default.
• W2320549531 hasConcept C50522688 @default.
• W2320549531 hasConcept C70410870 @default.
• W2320549531 hasConcept C71924100 @default.
• W2320549531 hasConceptScore W2320549531C126322002 @default.
• W2320549531 hasConceptScore W2320549531C144237770 @default.
• W2320549531 hasConceptScore W2320549531C148220186 @default.
• W2320549531 hasConceptScore W2320549531C154945302 @default.
• W2320549531 hasConceptScore W2320549531C159110408 @default.
• W2320549531 hasConceptScore W2320549531C160735492 @default.
• W2320549531 hasConceptScore W2320549531C162324750 @default.
• W2320549531 hasConceptScore W2320549531C171606756 @default.
• W2320549531 hasConceptScore W2320549531C177264268 @default.
• W2320549531 hasConceptScore W2320549531C1862650 @default.
• W2320549531 hasConceptScore W2320549531C198451711 @default.
• W2320549531 hasConceptScore W2320549531C199360897 @default.
• W2320549531 hasConceptScore W2320549531C23131810 @default.
• W2320549531 hasConceptScore W2320549531C2776436953 @default.
• W2320549531 hasConceptScore W2320549531C2779951463 @default.
• W2320549531 hasConceptScore W2320549531C2780801425 @default.
• W2320549531 hasConceptScore W2320549531C33191230 @default.
• W2320549531 hasConceptScore W2320549531C33923547 @default.
• W2320549531 hasConceptScore W2320549531C41008148 @default.
• W2320549531 hasConceptScore W2320549531C49453240 @default.
• W2320549531 hasConceptScore W2320549531C50522688 @default.
• W2320549531 hasConceptScore W2320549531C70410870 @default.
• W2320549531 hasConceptScore W2320549531C71924100 @default.
• W2320549531 hasLocation W23205495311 @default.
• W2320549531 hasOpenAccess W2320549531 @default.
• W2320549531 hasPrimaryLocation W23205495311 @default.
• W2320549531 hasRelatedWork W1573399941 @default.
• W2320549531 hasRelatedWork W2004481853 @default.
• W2320549531 hasRelatedWork W2005272443 @default.
• W2320549531 hasRelatedWork W2153476522 @default.
• W2320549531 hasRelatedWork W2313270173 @default.
• W2320549531 hasRelatedWork W2413072091 @default.
• W2320549531 hasRelatedWork W2465138992 @default.
• W2320549531 hasRelatedWork W2506139882 @default.
• W2320549531 hasRelatedWork W2513238386 @default.
• W2320549531 hasRelatedWork W2531118020 @default.
• W2320549531 hasRelatedWork W2718187725 @default.
• W2320549531 hasRelatedWork W2755048846 @default.
• W2320549531 hasRelatedWork W2789164638 @default.
• W2320549531 hasRelatedWork W2889064949 @default.
• W2320549531 hasRelatedWork W2912048043 @default.
• W2320549531 hasRelatedWork W2912137356 @default.
• W2320549531 hasRelatedWork W2916874807 @default.
• W2320549531 hasRelatedWork W2986155936 @default.
• W2320549531 hasRelatedWork W3173293812 @default.
• W2320549531 hasRelatedWork W2336076818 @default.
• W2320549531 isParatext "false" @default.
• W2320549531 isRetracted "false" @default.
• W2320549531 magId "2320549531" @default.
• W2320549531 workType "article" @default.