Matches in SemOpenAlex for { <https://semopenalex.org/work/W2327987029> ?p ?o ?g. }
Showing items 1 to 78 of
78
with 100 items per page.
- W2327987029 endingPage "157" @default.
- W2327987029 startingPage "157" @default.
- W2327987029 abstract "Nador et al. 5 first identified two types of primary effusion lymphoma (PEL) with different etiologic and genetic backgrounds. A striking finding of this report was that the presence of human herpes virus type 8 (HHV8) and the rearrangement of the c-MYC gene appeared to be mutually exclusive molecular events. 5 Thus, we proposed classifying HHV8+c-MYCG and HHV8−c-MYCR as PEL type I and type II respectively. 2 Because the lymphoma cells in our case showed neither HHV8 by polymerase chain reaction nor c-MYC gene rearrangement by cytogenetics or Southern blot analysis, we proposed a third category of PEL—HHV8−c-MYCG, or PEL type III. We considered that the patient reported by Ascoli et al. 1 could belong to either PEL type II or type III. 2 The demonstration of t(8;22)(q24;q11) by cytogenetics and the Burkitt morphology of the lymphoma cells in that patient argue for c-MYC gene involvement. However, it is well recognized that a cytogenetic breakpoint at 8q24 is not always synonymous with a rearranged c-MYC gene. 3,4,6 In the absence of more definitive proof of a c-MYC gene rearrangement, we subclassified tentatively the patient of Ascoli et al. 1 into the type III category. However, if a c-MYC gene rearrangement could be demonstrated by detailed analysis with genomic deoxyribonucleic acid, we would classify the patient as type II. We agree that HHV8− PEL represents a less well-characterized group than HHV8+ PEL, and that there is a need to identify more HHV8− PEL patients to achieve consensus in classifying these lymphomas. The initial report that the presence of HHV8− PEL was associated invariably with rearrangement of the c-MYC gene and Burkitt morphology, and our findings that point to the existence of HHV8−c-MYCG PEL with non-Burkitt morphology, suggests that PEL type III may represent a distinct category of these lymphomas. Ryo Ichinohasama M.D., Ph.D. Ikuo Miura M.D., Ph.D. John F. DeCoteau M.D." @default.
- W2327987029 created "2016-06-24" @default.
- W2327987029 creator A5012409078 @default.
- W2327987029 creator A5018021570 @default.
- W2327987029 creator A5024649691 @default.
- W2327987029 date "2000-01-01" @default.
- W2327987029 modified "2023-10-18" @default.
- W2327987029 title "Herpesvirus 8–Negative Primary Effusion Lymphoma Associated With Hepatitis C Virus" @default.
- W2327987029 cites W2016625585 @default.
- W2327987029 cites W2077626603 @default.
- W2327987029 cites W2085203792 @default.
- W2327987029 cites W2160508776 @default.
- W2327987029 cites W2166436914 @default.
- W2327987029 cites W2274022907 @default.
- W2327987029 doi "https://doi.org/10.1097/00000478-200001000-00030" @default.
- W2327987029 hasPublicationYear "2000" @default.
- W2327987029 type Work @default.
- W2327987029 sameAs 2327987029 @default.
- W2327987029 citedByCount "0" @default.
- W2327987029 crossrefType "journal-article" @default.
- W2327987029 hasAuthorship W2327987029A5012409078 @default.
- W2327987029 hasAuthorship W2327987029A5018021570 @default.
- W2327987029 hasAuthorship W2327987029A5024649691 @default.
- W2327987029 hasConcept C104317684 @default.
- W2327987029 hasConcept C133307689 @default.
- W2327987029 hasConcept C138626823 @default.
- W2327987029 hasConcept C153911025 @default.
- W2327987029 hasConcept C159047783 @default.
- W2327987029 hasConcept C174475383 @default.
- W2327987029 hasConcept C203014093 @default.
- W2327987029 hasConcept C206936463 @default.
- W2327987029 hasConcept C2522874641 @default.
- W2327987029 hasConcept C2779338263 @default.
- W2327987029 hasConcept C2779594685 @default.
- W2327987029 hasConcept C2992511266 @default.
- W2327987029 hasConcept C30481170 @default.
- W2327987029 hasConcept C49105822 @default.
- W2327987029 hasConcept C54355233 @default.
- W2327987029 hasConcept C71924100 @default.
- W2327987029 hasConcept C86803240 @default.
- W2327987029 hasConceptScore W2327987029C104317684 @default.
- W2327987029 hasConceptScore W2327987029C133307689 @default.
- W2327987029 hasConceptScore W2327987029C138626823 @default.
- W2327987029 hasConceptScore W2327987029C153911025 @default.
- W2327987029 hasConceptScore W2327987029C159047783 @default.
- W2327987029 hasConceptScore W2327987029C174475383 @default.
- W2327987029 hasConceptScore W2327987029C203014093 @default.
- W2327987029 hasConceptScore W2327987029C206936463 @default.
- W2327987029 hasConceptScore W2327987029C2522874641 @default.
- W2327987029 hasConceptScore W2327987029C2779338263 @default.
- W2327987029 hasConceptScore W2327987029C2779594685 @default.
- W2327987029 hasConceptScore W2327987029C2992511266 @default.
- W2327987029 hasConceptScore W2327987029C30481170 @default.
- W2327987029 hasConceptScore W2327987029C49105822 @default.
- W2327987029 hasConceptScore W2327987029C54355233 @default.
- W2327987029 hasConceptScore W2327987029C71924100 @default.
- W2327987029 hasConceptScore W2327987029C86803240 @default.
- W2327987029 hasIssue "1" @default.
- W2327987029 hasLocation W23279870291 @default.
- W2327987029 hasOpenAccess W2327987029 @default.
- W2327987029 hasPrimaryLocation W23279870291 @default.
- W2327987029 hasRelatedWork W1567322571 @default.
- W2327987029 hasRelatedWork W2000066178 @default.
- W2327987029 hasRelatedWork W2059754755 @default.
- W2327987029 hasRelatedWork W2094747462 @default.
- W2327987029 hasRelatedWork W2155814353 @default.
- W2327987029 hasRelatedWork W216208948 @default.
- W2327987029 hasRelatedWork W221387354 @default.
- W2327987029 hasRelatedWork W2323340928 @default.
- W2327987029 hasRelatedWork W2437901702 @default.
- W2327987029 hasRelatedWork W4236085334 @default.
- W2327987029 hasVolume "24" @default.
- W2327987029 isParatext "false" @default.
- W2327987029 isRetracted "false" @default.
- W2327987029 magId "2327987029" @default.
- W2327987029 workType "article" @default.