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- W2332157306 abstract "Parylene C is a polymer well-known for its inertness and chemical resistance, thus ideal for covering and sealing 3D substrates and structures by conformal coating. In the present study, the Parylene C surface is modified by functionalization with pH-responsive poly(methacrylic acid) microgels either over the whole surface, or in a pattern through a poly(dimethylsiloxane) stamp. The surface functionalization consists of two phases: first, an oxygen plasma treatment is used to make the surface superhydrophilic, inducing the formation of polar functional groups and surface topography modifications; then, the plasma-treated samples are functionalized by drop casting a solution of pH-responsive microgels, or in a pattern via microcontact printing of the same solution. While both techniques, namely, drop casting and microcontact printing, are easy to use, fast, and cheap, the microcontact printing was found to provide a more homogeneous functionalization and to be applicable to any shape of substrate. The functionalization effectiveness was tested by the repeated uptake and release of a fluorescent labeled monoclonal CD4 antibody at different pH values, thus suggesting a new sensing approach." @default.
- W2332157306 created "2016-06-24" @default.
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- W2332157306 date "2014-09-03" @default.
- W2332157306 modified "2023-10-03" @default.
- W2332157306 title "Parylene C Surface Functionalization and Patterning with pH-Responsive Microgels" @default.
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- W2332157306 doi "https://doi.org/10.1021/am502467y" @default.
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