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• W2344143359 abstract "ABSTRACT Objective. The objective of this study is to analyze the inci-dence and the role of MYC and BCL2 protein expression in patients with diffuse large B-cell lymphoma (DLBCL) and to compare data of histological, immunohistochemical, genetic, and molecular analyses with clinical characteristics. Methods. 62 patients with confirmed diffuse large B-cell lymphoma (DLBCL) were enrolled in the study; they under-went treatment according to the original modified protocol NHL-BFM-90  R in the Hematology Research Center un-der the Ministry of Health of the Russian Federation. A refer-ence group consisted of 13 DLBCL patients who underwent СНОР-like  R therapy. In all observations, histological and immunohistochemical tests were performed in archived bi-opsy samples of a tumor tissue or a lymph node (paraffin blocks) using BCL2 (clone 124, Dako) and MYC antibod-ies (clone Y69, Epitomics). Based on C.P. Hans’s algorithm (2004), GCB and non-GCB immunohistochemical subtypes of DLBCL were determined. Standard cytogenetic tests (" @default.
• W2344143359 created "2016-06-24" @default.
• W2344143359 creator A5082837454 @default.
• W2344143359 date "2015-01-01" @default.
• W2344143359 modified "2023-09-23" @default.
• W2344143359 title "MYC and BCL2 Protein Expression in Patients with Diffuse Large B-cell Lymphoma" @default.
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• W2344143359 hasPublicationYear "2015" @default.
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