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- W2356011103 abstract "Objective To establish an HPLC method for the determination of gatifloxacin in the gatifloxacin ophthalmic gel. Methods The stationary phase was Nucleosil 120-5 C_ 18 column (4.0 mm×250 mm, 5 μm) ,the mobile phase methanol-0.007 mol·L -1 KH_ 2 PO_ 4 buffer (pH adjusted to 4.0 with H_ 3 PO_ 4 ) (30∶70)with a flow rate of 1.0 mL·min -1 . The detect wavelength 286 nm ,and the column temperature 30℃. Results The calibration curve was linear within the range of 10-50 μg·mL -1 , the average recovery was 99.3%( RSD =0.63%, n =6). Conclusion This method is accurate and simple,it can be used for the determination of gatifloxacin in gatifloxacin ophthalmic gel ." @default.
- W2356011103 created "2016-06-24" @default.
- W2356011103 creator A5017557616 @default.
- W2356011103 date "2005-01-01" @default.
- W2356011103 modified "2023-09-25" @default.
- W2356011103 title "Determination of Gatifloxacin in Gatifloxacin Ophthalmic Gel by HPLC" @default.
- W2356011103 hasPublicationYear "2005" @default.
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