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- W2377995094 abstract "A kind of microaqueous|organic two phase system was selected for the resolution of Naproxen. CCL(Candida cylindracea lipase)with high enantioselectivity for Naproxen ester was immobilized on celite by adsorption. Naproxen chloroethyl ester as an actived ester had been synthesized and used to enhance the rate of hydrolysis catalyzed by CCL, and the conversion of which reached 35% after 24 h reaction. The reaction rate of this actived ester is far more rapid than naproxen methyl ester. Inhibition appeared when the concentration of naproxen chloroethyl ester is too high. The influence of water amount on reaction catalyzed by enzyme was briefly discussed. The reaction rate is the largest when water has a monolayer distribution on the surface of carrier." @default.
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- W2377995094 date "1999-01-01" @default.
- W2377995094 modified "2023-09-25" @default.
- W2377995094 title "Influence of Substrate and Water Amount on the Asymmetric Resolution of Naproxen by Lipase" @default.
- W2377995094 hasPublicationYear "1999" @default.
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