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- W2385508093 abstract "Objective To observe the expression of vitamin D receptor (VDR) protein in aging osteoblast, investigate the effects of Bushen (Chinese medicine) on the expression of VDR,and try to provide new mechanisms of Chinese medicine on bone formation.Methods Rat osteoblast from different age donors(6 months and 16 months) were isolated and cultured by the tissue-fragment-migrating-growth method.Their biological characteristic were observed by phase-contrast microscope, mineralizing nodule staining and electromicroscope. VDR protein staining was performed with immunohistolochemistry,and the expression of VDR protein was examined through Western blot.Results Immunohistolochemistry and Western blot showed that Bushenyijing,Gubenzhuanggu,Jinkuishenqi upregulated the expression of VDR protein among Bushen Chinese medicine in aging osteoblast, but the expression was different in Zhibaidihuang.Conclusions The expression of VDR protein was upregulated by Bushenyijing,Gubenzhuanggu,Jinkuishenqi with aging osteoblast,which was different in Zhibaidihuang." @default.
- W2385508093 created "2016-06-24" @default.
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- W2385508093 date "2006-01-01" @default.
- W2385508093 modified "2023-09-23" @default.
- W2385508093 title "Effects of Chinese medicine (Bushen) on expression of VDR protein in aging osteoblast" @default.
- W2385508093 hasPublicationYear "2006" @default.
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