Matches in SemOpenAlex for { <https://semopenalex.org/work/W2389185332> ?p ?o ?g. }
Showing items 1 to 73 of
73
with 100 items per page.
- W2389185332 abstract "Thrombin, collagen, platelet activating factor, arachidonic acid, adenosine diphosphate, adrenaline,serotonin and other platelet agonists can stimulate platelet to generate a series of complex signal transduction and then cause platelet physiological responses including deformation,granule release and aggregation etc. Although platelet activation and aggregation at sites of vascular injury is an essential step in coagulation process,excessive platelet accumulation leads to the formation of occlusive thrombi, which are responsible for acute ischemic events. Therefore,anti-platelet therapy is an important approach for the treatment of thrombotic diseases. Currently used anti-platelet drugs,which primarily act through receptors and / or signaling molecules in activation pathways,achieving their effects by inhibiting platelet receptors or blocking signal transmission. In this review,the targets of the above-mentioned platelet agonists and their specific activation mechanisms are introduced; receptor antagonists and other anti-platelet drugs are also summarized." @default.
- W2389185332 created "2016-06-24" @default.
- W2389185332 creator A5020059398 @default.
- W2389185332 date "2014-01-01" @default.
- W2389185332 modified "2023-09-22" @default.
- W2389185332 title "Mechanism of agonist-induced platelet activation and research progress of anti-platelet drugs" @default.
- W2389185332 hasPublicationYear "2014" @default.
- W2389185332 type Work @default.
- W2389185332 sameAs 2389185332 @default.
- W2389185332 citedByCount "0" @default.
- W2389185332 crossrefType "journal-article" @default.
- W2389185332 hasAuthorship W2389185332A5020059398 @default.
- W2389185332 hasConcept C126322002 @default.
- W2389185332 hasConcept C159973064 @default.
- W2389185332 hasConcept C170493617 @default.
- W2389185332 hasConcept C185592680 @default.
- W2389185332 hasConcept C203014093 @default.
- W2389185332 hasConcept C2777292125 @default.
- W2389185332 hasConcept C2777399203 @default.
- W2389185332 hasConcept C2778382381 @default.
- W2389185332 hasConcept C2778938600 @default.
- W2389185332 hasConcept C2993802102 @default.
- W2389185332 hasConcept C3018697912 @default.
- W2389185332 hasConcept C49059817 @default.
- W2389185332 hasConcept C55493867 @default.
- W2389185332 hasConcept C62478195 @default.
- W2389185332 hasConcept C71924100 @default.
- W2389185332 hasConcept C89560881 @default.
- W2389185332 hasConcept C98274493 @default.
- W2389185332 hasConceptScore W2389185332C126322002 @default.
- W2389185332 hasConceptScore W2389185332C159973064 @default.
- W2389185332 hasConceptScore W2389185332C170493617 @default.
- W2389185332 hasConceptScore W2389185332C185592680 @default.
- W2389185332 hasConceptScore W2389185332C203014093 @default.
- W2389185332 hasConceptScore W2389185332C2777292125 @default.
- W2389185332 hasConceptScore W2389185332C2777399203 @default.
- W2389185332 hasConceptScore W2389185332C2778382381 @default.
- W2389185332 hasConceptScore W2389185332C2778938600 @default.
- W2389185332 hasConceptScore W2389185332C2993802102 @default.
- W2389185332 hasConceptScore W2389185332C3018697912 @default.
- W2389185332 hasConceptScore W2389185332C49059817 @default.
- W2389185332 hasConceptScore W2389185332C55493867 @default.
- W2389185332 hasConceptScore W2389185332C62478195 @default.
- W2389185332 hasConceptScore W2389185332C71924100 @default.
- W2389185332 hasConceptScore W2389185332C89560881 @default.
- W2389185332 hasConceptScore W2389185332C98274493 @default.
- W2389185332 hasLocation W23891853321 @default.
- W2389185332 hasOpenAccess W2389185332 @default.
- W2389185332 hasPrimaryLocation W23891853321 @default.
- W2389185332 hasRelatedWork W1119463885 @default.
- W2389185332 hasRelatedWork W1984087125 @default.
- W2389185332 hasRelatedWork W2020019411 @default.
- W2389185332 hasRelatedWork W2022537971 @default.
- W2389185332 hasRelatedWork W2054036069 @default.
- W2389185332 hasRelatedWork W2076003026 @default.
- W2389185332 hasRelatedWork W2095524167 @default.
- W2389185332 hasRelatedWork W2116924861 @default.
- W2389185332 hasRelatedWork W2128143119 @default.
- W2389185332 hasRelatedWork W2157334944 @default.
- W2389185332 hasRelatedWork W2171267045 @default.
- W2389185332 hasRelatedWork W2172570864 @default.
- W2389185332 hasRelatedWork W2269541827 @default.
- W2389185332 hasRelatedWork W2300041291 @default.
- W2389185332 hasRelatedWork W2519185857 @default.
- W2389185332 hasRelatedWork W2593907567 @default.
- W2389185332 hasRelatedWork W2805841471 @default.
- W2389185332 hasRelatedWork W2904545963 @default.
- W2389185332 hasRelatedWork W624099863 @default.
- W2389185332 hasRelatedWork W856346509 @default.
- W2389185332 isParatext "false" @default.
- W2389185332 isRetracted "false" @default.
- W2389185332 magId "2389185332" @default.
- W2389185332 workType "article" @default.