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- W2389680394 abstract "Objective To investigate the diagnostic value of plasma brain natriuretic peptide(BNP) in senile patients with normal eject fraction heart failure(NEFHF).Methods The blood samples in 117 senile patients(age 75 years) with NEFHF and 71 healthy senile volunteers(age 75 years) were collected,and the concentrations of BNP in the blood samples were detected by electrochemiluminescence immunoassay,at the same time,the parameters including LVEF,E/A,E/Vp were detected by echocardiography.The changes of concentration of plasma BNP in patients with NEFHF were observed and compared with those in healthy senile subjects,and the performance curve was analyzed for all the subjects,furthermore,the correlation between BNP and cardiac diastolic dysfunction classification was analyzed.Results The levels of plasma BNP in the senile patients with NEFHF were significantly higher than those in healthy senile subjects(P0.01),and the area under curve which was used to diagnose NEFHF was 0.746(95%CI:0.677~0.815).When the cut off value was 1 500pg/ml,the diagnostic sensitivity and specificity were 68% and 62%,respectively.The levels of BNP were closely correlated with cardiac diastolic dysfunction classification.Conclusion The levels of plasma BNP are obviously increased in senile patients with NEFHF,which has important diagnostic value." @default.
- W2389680394 created "2016-06-24" @default.
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- W2389680394 date "2012-01-01" @default.
- W2389680394 modified "2023-09-24" @default.
- W2389680394 title "The diagnostic value of plasma BNP in the senile patients with normal eject fraction heart failure" @default.
- W2389680394 hasPublicationYear "2012" @default.
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