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- W2392752449 abstract "Objective:To explore the effect of rituximab combined with GDP regimen in the treatment of recurrent and refractory diffuse large B-cell lymphoma(DLBCL)and adverse effect.Method:A total of 28 cases of refractory and relapsed DLBCL from January 2009 to December 2013 in our hospital,we used the combination of rituximab and GDP chemotherapy(rituximab 375 mg/m2 d0,gemcitabine 1 000 mg/m2 d1,8,cisplatin 25 mg/m2d1-3,dexamethasone 40mg/d d1-4),21 days for a course of treatment.Curative effect and adverse reaction evaluation completed after two courses.Result:Followed up for 9-58 months,13 cases achieved complete remission,9cases achieved partial remission,1patients with stable disease,5patients with disease progression,the total efficiency was 78.6%.Common adverse reactions were myelosuppression and gastrointestinal tract reaction.Conclusion:Rituximab combined with GDP is a safe and effective saving scheme for relapsed refractory DLBCL." @default.
- W2392752449 created "2016-06-24" @default.
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- W2392752449 date "2015-01-01" @default.
- W2392752449 modified "2023-09-27" @default.
- W2392752449 title "Observation of the curative effect of rituximab combined with GDP regimen in the treatment of recurrent and refractory diffuse large B-cell lymphoma" @default.
- W2392752449 hasPublicationYear "2015" @default.
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