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- W2462936332 abstract "Objective To investigate the eradicate effect of Helicobacter pylori in differentiated thyroid cancer patients who underwent 131I therapy. Materials and methods A total of 130 patients with differentiated thyroid cancer underwent 131I treatment. None of the patients had a history of stomach-related diseases. The 13C-urea breath test (UBT) was carried out for H. pylori examination before 131I treatment. The cut-off value for 13C-UBT was 4%. For H. pylori test-positive patients, a second 13C-UBT was performed 4–6 weeks after 131I treatment. T-tests were used to compare the difference before and 4–6 weeks after 131I treatment. Results A total of 42 of 130 (32.31%) patients were H. pylori positive. The average value of H. pylori was 28.36% before 131I, whereas the value was 18.18% after 131I therapy. A significant decrease in 13C-UBT was found after 131I treatment compared with before therapy (P<0.01). Conclusion Our preliminary data showed that 131I exerts certain eradication effects on H. pylori, which could provide a new approach to multidrug resistance pathogens. As the exact molecular mechanism of this phenomenon is still unclear, future clinical applications of this anecdotal finding require further assessments." @default.
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- W2462936332 date "2016-11-01" @default.
- W2462936332 modified "2023-10-12" @default.
- W2462936332 title "Iodine-131 in Helicobacter pylori-positive patients" @default.
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- W2462936332 doi "https://doi.org/10.1097/mnm.0000000000000564" @default.
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