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- W2464070637 abstract "Several contrast agents have been approved in the United States for radiographic imaging purposes. Most of the older ionic, high-osmolar contrast agents are no longer used because of their side effect profile. Therefore, newer nonionic, low or iso-osmolar contrast agents have been widely accepted as an alternative due to their improved tolerability and safety. We investigated the thrombogenicity of the 6 different nonionic radiocontrast media in terms of their platelet reactivity and noted some minor differences among them. In the 50% contrast concentration group, all of the nonionic contrast agents inhibited aggregation, whereas in the 10% contrast concentration group, all agents showed similar aggregation curves in comparison to the normal control. At 50% contrast concentration, the inhibitory effect of aggregation appeared to be related to the inhibition of calcium mobilization, which may be one of the mechanistic effects." @default.
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- W2464070637 date "2008-07-01" @default.
- W2464070637 modified "2023-09-26" @default.
- W2464070637 title "Risk of thrombogenicity among nonionic radiocontrast agents." @default.
- W2464070637 hasPubMedId "https://pubmed.ncbi.nlm.nih.gov/18599893" @default.
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