Matches in SemOpenAlex for { <https://semopenalex.org/work/W2466294786> ?p ?o ?g. }
Showing items 1 to 72 of
72
with 100 items per page.
- W2466294786 endingPage "93" @default.
- W2466294786 startingPage "387" @default.
- W2466294786 abstract "Melatonin disturbs the reproductive process in seasonal but not in continuous breeders: however, it delays sexual development in the rat. The testicular function of rats injected daily with melatonin from 20 up to 25, 30, 35 or 40 days of age was analyzed. The spermatogenic and androgenic activity of testes was assessed by light microscopy and by the capacity for binding hCG and producing testosterone in vitro, respectively. In addition, LH, FSH and testosterone plasma levels were measured and 3B-hydroxysteroid dehydrogenase activity of Leydig cells was assessed histochemically to aid in the interpretation of results. Rats treated with melatonin for 15 or 20 days presented at the end of the juvenile period, abnormal progression of spermatogenesis and decreased ability of their Leydig cells to produce testosterone both in vivo and in vitro. This was associated with a lower number of binding sites for hCG and diminished production of testosterone in response to receptor and post-receptor mediated stimulation of steroidogenesis. Melatonin caused a marked decrease in LH serum levels. The diminished LH supply to the testis probably interfered with differentiation or impaired the functional ability of Leydig cells. As a consequence, testicular testosterone production was insufficient to support normal spermatogenic progression and growth and development of the sexual accessory organs." @default.
- W2466294786 created "2016-07-22" @default.
- W2466294786 creator A5002991557 @default.
- W2466294786 creator A5028212992 @default.
- W2466294786 creator A5034350227 @default.
- W2466294786 creator A5060846812 @default.
- W2466294786 date "1989-12-01" @default.
- W2466294786 modified "2023-10-18" @default.
- W2466294786 title "Testicular function of sexually immature rats chronically treated with melatonin." @default.
- W2466294786 hasPubMedId "https://pubmed.ncbi.nlm.nih.gov/2488537" @default.
- W2466294786 hasPublicationYear "1989" @default.
- W2466294786 type Work @default.
- W2466294786 sameAs 2466294786 @default.
- W2466294786 citedByCount "11" @default.
- W2466294786 countsByYear W24662947862015 @default.
- W2466294786 countsByYear W24662947862016 @default.
- W2466294786 countsByYear W24662947862019 @default.
- W2466294786 countsByYear W24662947862022 @default.
- W2466294786 crossrefType "journal-article" @default.
- W2466294786 hasAuthorship W2466294786A5002991557 @default.
- W2466294786 hasAuthorship W2466294786A5028212992 @default.
- W2466294786 hasAuthorship W2466294786A5034350227 @default.
- W2466294786 hasAuthorship W2466294786A5060846812 @default.
- W2466294786 hasConcept C123765429 @default.
- W2466294786 hasConcept C126322002 @default.
- W2466294786 hasConcept C134018914 @default.
- W2466294786 hasConcept C150903083 @default.
- W2466294786 hasConcept C170493617 @default.
- W2466294786 hasConcept C207001950 @default.
- W2466294786 hasConcept C24998067 @default.
- W2466294786 hasConcept C2777736315 @default.
- W2466294786 hasConcept C2778182776 @default.
- W2466294786 hasConcept C2778575703 @default.
- W2466294786 hasConcept C2779279991 @default.
- W2466294786 hasConcept C71315377 @default.
- W2466294786 hasConcept C71924100 @default.
- W2466294786 hasConcept C86803240 @default.
- W2466294786 hasConceptScore W2466294786C123765429 @default.
- W2466294786 hasConceptScore W2466294786C126322002 @default.
- W2466294786 hasConceptScore W2466294786C134018914 @default.
- W2466294786 hasConceptScore W2466294786C150903083 @default.
- W2466294786 hasConceptScore W2466294786C170493617 @default.
- W2466294786 hasConceptScore W2466294786C207001950 @default.
- W2466294786 hasConceptScore W2466294786C24998067 @default.
- W2466294786 hasConceptScore W2466294786C2777736315 @default.
- W2466294786 hasConceptScore W2466294786C2778182776 @default.
- W2466294786 hasConceptScore W2466294786C2778575703 @default.
- W2466294786 hasConceptScore W2466294786C2779279991 @default.
- W2466294786 hasConceptScore W2466294786C71315377 @default.
- W2466294786 hasConceptScore W2466294786C71924100 @default.
- W2466294786 hasConceptScore W2466294786C86803240 @default.
- W2466294786 hasIssue "4" @default.
- W2466294786 hasLocation W24662947861 @default.
- W2466294786 hasOpenAccess W2466294786 @default.
- W2466294786 hasPrimaryLocation W24662947861 @default.
- W2466294786 hasRelatedWork W1978552944 @default.
- W2466294786 hasRelatedWork W1992486010 @default.
- W2466294786 hasRelatedWork W1992910440 @default.
- W2466294786 hasRelatedWork W2044610579 @default.
- W2466294786 hasRelatedWork W2089616824 @default.
- W2466294786 hasRelatedWork W2107754935 @default.
- W2466294786 hasRelatedWork W2139628794 @default.
- W2466294786 hasRelatedWork W2158469686 @default.
- W2466294786 hasRelatedWork W2305945525 @default.
- W2466294786 hasRelatedWork W2466294786 @default.
- W2466294786 hasVolume "22" @default.
- W2466294786 isParatext "false" @default.
- W2466294786 isRetracted "false" @default.
- W2466294786 magId "2466294786" @default.
- W2466294786 workType "article" @default.