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- W2553026850 abstract ". Penetration through the basement membrane is a critical step during the metastatic process, and has been linked to the formation of membrane superstructures called invadopodia 2 . While being made of multiple substances, a notable component are matrix metalloproteinases (MMPs), and specifically Membrane-type 1 MMP (MT1-MMP), otherwise known as matrix metalloproteinase 14 (MMP-14). This enzyme is crucial for basement membrane and interstitial matrix degradation 3 , and has been shown to play a critical role in conferring cells with the ability to penetrate the extracellular matrix (ECM) 4" @default.
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- W2553026850 date "2015-01-01" @default.
- W2553026850 modified "2023-09-27" @default.
- W2553026850 title "Quantification of MMP Activity and Inhibition in a 3D Tumor Invasion Model Using a Novel Fluorescence Detection Technology and Digital Widefield" @default.
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