FRINK Linked Data Fragments server

Matches in SemOpenAlex for { <https://semopenalex.org/work/W2614645420> ?p ?o ?g. }

• W2614645420 endingPage "1295" @default.
• W2614645420 startingPage "1290" @default.
• W2614645420 abstract "Background: Acute graft-versus-host disease (aGVHD) is a common and severe complication of allogeneic hematopoietic stem cell transplantation (allo-HSCT). Some studies have found that the presence of certain specific human leukocyte antigen (HLA) loci could affect the occurrence of aGVHD. Meanwhile, the impact of HLA haplotypes on aGVHD has been rarely studied. This study aimed to investigate the effects of HLA loci and haplotypes on intestinal aGVHD. Methods: Totally, 345 consecutive patients undergoing first HLA-matched sibling peripheral blood stem cell transplantation (PBSCT) from February 2004 to June 2013 at Institute of Hematology and Blood Diseases Hospital, Chinese Academy of Medical Sciences and Peking Union Medical College, were enrolled in this study. HLA loci and haplotypes of recipients with frequency over 5% were searched and their effects on intestinal aGVHD were investigated. Other important factors including donor age, recipient age, donor-recipient sex combinations, and conditioning regimens were also evaluated using logistic regression. Pure upper gastrointestinal tract aGVHD without diarrhea was excluded because the histological proof was unavailable. The follow-up end-point was 6 months after HSCT. Results: The cumulative incidence of intestinal aGVHD was 19.4%, with 18.0% of the patients classified as classic aGVHD and 1.4% as persistent, recurrent, or late aGVHD. Multivariate analysis showed that HLA-A31 locus (odds ratio [OR] 2.893, 95% confidence interval [CI] [1.054, 7.935], P = 0.039), HLA B40-DR15 (OR 3.133, 95% CI [1.250, 7.857], P = 0.015), and HLA B46-DR9 haplotypes (OR 2.580, 95% CI [1.070, 6.220], P = 0.035), female donor for male recipient (OR 2.434, 95% CI [1.319, 4.493], P = 0.004) were risk factors for intestinal aGVHD. Conclusion: The presence of certain HLA loci and haplotypes may influence the occurrence of intestinal aGVHD in PBSCT with HLA-identical sibling donors." @default.
• W2614645420 created "2017-05-26" @default.
• W2614645420 creator A5009936715 @default.
• W2614645420 creator A5029862222 @default.
• W2614645420 creator A5032280848 @default.
• W2614645420 creator A5035322817 @default.
• W2614645420 creator A5075620860 @default.
• W2614645420 date "2017-06-05" @default.
• W2614645420 modified "2023-09-27" @default.
• W2614645420 title "Impact of Human Leukocyte Antigen Loci and Haplotypes on Intestinal Acute Graft-versus-host Disease after Human Leukocyte Antigen-matched Sibling Peripheral Blood Stem Cell Transplantation" @default.
• W2614645420 cites W1491993932 @default.
• W2614645420 cites W1581580944 @default.
• W2614645420 cites W1791490072 @default.
• W2614645420 cites W181318888 @default.
• W2614645420 cites W1888395931 @default.
• W2614645420 cites W1965430571 @default.
• W2614645420 cites W1979100130 @default.
• W2614645420 cites W1981985962 @default.
• W2614645420 cites W1985560867 @default.
• W2614645420 cites W1994983630 @default.
• W2614645420 cites W2004265022 @default.
• W2614645420 cites W2005768104 @default.
• W2614645420 cites W2011325093 @default.
• W2614645420 cites W2015051235 @default.
• W2614645420 cites W2016203390 @default.
• W2614645420 cites W2016409678 @default.
• W2614645420 cites W2025405969 @default.
• W2614645420 cites W2031364732 @default.
• W2614645420 cites W2033344216 @default.
• W2614645420 cites W2036348884 @default.
• W2614645420 cites W2039191209 @default.
• W2614645420 cites W2039422996 @default.
• W2614645420 cites W2040343055 @default.
• W2614645420 cites W2041572543 @default.
• W2614645420 cites W2044560944 @default.
• W2614645420 cites W2046297314 @default.
• W2614645420 cites W2052365715 @default.
• W2614645420 cites W2058526416 @default.
• W2614645420 cites W2065367621 @default.
• W2614645420 cites W2068399493 @default.
• W2614645420 cites W2070757524 @default.
• W2614645420 cites W2078021975 @default.
• W2614645420 cites W2080128014 @default.
• W2614645420 cites W2091192905 @default.
• W2614645420 cites W2091713447 @default.
• W2614645420 cites W2110458118 @default.
• W2614645420 cites W2118683743 @default.
• W2614645420 cites W2123513217 @default.
• W2614645420 cites W2129092670 @default.
• W2614645420 cites W2129789149 @default.
• W2614645420 cites W2136225415 @default.
• W2614645420 cites W2142236214 @default.
• W2614645420 cites W2155996961 @default.
• W2614645420 cites W2161867137 @default.
• W2614645420 cites W2161880291 @default.
• W2614645420 cites W2171415926 @default.
• W2614645420 cites W2222775964 @default.
• W2614645420 cites W2276105096 @default.
• W2614645420 cites W2324304000 @default.
• W2614645420 cites W2328954499 @default.
• W2614645420 cites W2379365975 @default.
• W2614645420 cites W2401269987 @default.
• W2614645420 cites W2618073389 @default.
• W2614645420 cites W4239549478 @default.
• W2614645420 cites W8882568 @default.
• W2614645420 doi "https://doi.org/10.4103/0366-6999.206356" @default.
• W2614645420 hasPubMedCentralId "https://www.ncbi.nlm.nih.gov/pmc/articles/5455037" @default.
• W2614645420 hasPubMedId "https://pubmed.ncbi.nlm.nih.gov/28524827" @default.
• W2614645420 hasPublicationYear "2017" @default.
• W2614645420 type Work @default.
• W2614645420 sameAs 2614645420 @default.
• W2614645420 citedByCount "0" @default.
• W2614645420 crossrefType "journal-article" @default.
• W2614645420 hasAuthorship W2614645420A5009936715 @default.
• W2614645420 hasAuthorship W2614645420A5029862222 @default.
• W2614645420 hasAuthorship W2614645420A5032280848 @default.
• W2614645420 hasAuthorship W2614645420A5035322817 @default.
• W2614645420 hasAuthorship W2614645420A5075620860 @default.
• W2614645420 hasBestOaLocation W26146454201 @default.
• W2614645420 hasConcept C104317684 @default.
• W2614645420 hasConcept C126322002 @default.
• W2614645420 hasConcept C147483822 @default.
• W2614645420 hasConcept C156957248 @default.
• W2614645420 hasConcept C180754005 @default.
• W2614645420 hasConcept C188280979 @default.
• W2614645420 hasConcept C194409129 @default.
• W2614645420 hasConcept C197754878 @default.
• W2614645420 hasConcept C203014093 @default.
• W2614645420 hasConcept C2777408962 @default.
• W2614645420 hasConcept C2779972918 @default.
• W2614645420 hasConcept C2911091166 @default.
• W2614645420 hasConcept C54355233 @default.
• W2614645420 hasConcept C71924100 @default.
• W2614645420 hasConcept C86803240 @default.
• W2614645420 hasConcept C90924648 @default.
• W2614645420 hasConceptScore W2614645420C104317684 @default.
• W2614645420 hasConceptScore W2614645420C126322002 @default.
• W2614645420 hasConceptScore W2614645420C147483822 @default.

• next