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- W2730181254 abstract "Lung cancer is the leading cause of cancer deaths worldwide. Clinically, the treatment of non-small cell lung cancer (NSCLC) can be improved by the early detection and risk screening among population. To meet this need, here we describe in detail a shotgun following the targeted proteomics workflow that we previously applied for human plasma analysis, which involves (1) the application of extensive peptide-level fractionation coupled with label-free quantitative proteomics for the discovery of plasma biomarker candidates for lung cancer and (2) the usage of the multiple reaction monitoring (MRM) assays for the follow-up validations in the verification phase. The workflow features simplicity, low cost, high transferability, high robustness, and flexibility with specific instrumental settings." @default.
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- W2730181254 date "2017-01-01" @default.
- W2730181254 modified "2023-09-26" @default.
- W2730181254 title "Shotgun and Targeted Plasma Proteomics to Predict Prognosis of Non-Small Cell Lung Cancer" @default.
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- W2730181254 doi "https://doi.org/10.1007/978-1-4939-7057-5_26" @default.
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