Matches in SemOpenAlex for { <https://semopenalex.org/work/W2783500575> ?p ?o ?g. }
Showing items 1 to 99 of
99
with 100 items per page.
- W2783500575 endingPage "423" @default.
- W2783500575 startingPage "419" @default.
- W2783500575 abstract "Intravenous magnesium is routinely administered in intensive care units (ICU) to treat arrhythmias after cardiothoracic surgery. There are no data on the pharmacokinetics of continuous magnesium infusion therapy.To investigate the pharmacokinetics of continuous magnesium infusion, focusing on serum and urinary magnesium concentration, volume of distribution and half-life.We administered a 10 mmol bolus of magnesium-sulfate followed by a continuous infusion of 3 mmol/h for 12 h in twenty cardiac surgery patients. We obtained blood and urine samples prior to magnesium administration and after one, six, and 12 h.Median magnesium levels increased from 1.09 (IQR 1.00-1.23) mmol/L to 1.59 (1.45-1.76) mmol/L after 60 min (p < .001), followed by 1.53 (1.48-1.71) and 1.59 (1.48-1.76) mmol/L after 6 and 12 h. Urinary magnesium concentration increased from 9.2 (5.0-13.9) mmol/L to 17 (13.6-21.6) mmol/L after 60 min (p < .001). Cumulative urinary magnesium excretion was 28 mmol (60.9% of the dose given). The volume of distribution was 0.25 (0.22-0.30) L/kg. There were no episodes of severe hypermagnesemia (≥3 mmol/L).Combined bolus and continuous magnesium infusion therapy leads to a significant and stable increase in magnesium serum concentration despite increased renal excretion and redistribution." @default.
- W2783500575 created "2018-01-26" @default.
- W2783500575 creator A5006188476 @default.
- W2783500575 creator A5011216396 @default.
- W2783500575 creator A5011993928 @default.
- W2783500575 creator A5026337576 @default.
- W2783500575 creator A5037230392 @default.
- W2783500575 creator A5050892378 @default.
- W2783500575 creator A5069889138 @default.
- W2783500575 creator A5072912292 @default.
- W2783500575 date "2018-04-01" @default.
- W2783500575 modified "2023-10-07" @default.
- W2783500575 title "Magnesium supplementation: Pharmacokinetics in cardiac surgery patients with normal renal function" @default.
- W2783500575 cites W1978009093 @default.
- W2783500575 cites W1979040759 @default.
- W2783500575 cites W1982104967 @default.
- W2783500575 cites W2034173662 @default.
- W2783500575 cites W2082218147 @default.
- W2783500575 cites W2087431627 @default.
- W2783500575 cites W2117462186 @default.
- W2783500575 cites W2121075987 @default.
- W2783500575 cites W2126553012 @default.
- W2783500575 cites W2129012562 @default.
- W2783500575 cites W2159667117 @default.
- W2783500575 cites W2224357665 @default.
- W2783500575 cites W2277692262 @default.
- W2783500575 cites W2559743312 @default.
- W2783500575 cites W4206100856 @default.
- W2783500575 cites W4294882136 @default.
- W2783500575 doi "https://doi.org/10.1016/j.jcrc.2018.01.011" @default.
- W2783500575 hasPubMedId "https://pubmed.ncbi.nlm.nih.gov/29353118" @default.
- W2783500575 hasPublicationYear "2018" @default.
- W2783500575 type Work @default.
- W2783500575 sameAs 2783500575 @default.
- W2783500575 citedByCount "5" @default.
- W2783500575 countsByYear W27835005752019 @default.
- W2783500575 countsByYear W27835005752020 @default.
- W2783500575 countsByYear W27835005752021 @default.
- W2783500575 countsByYear W27835005752023 @default.
- W2783500575 crossrefType "journal-article" @default.
- W2783500575 hasAuthorship W2783500575A5006188476 @default.
- W2783500575 hasAuthorship W2783500575A5011216396 @default.
- W2783500575 hasAuthorship W2783500575A5011993928 @default.
- W2783500575 hasAuthorship W2783500575A5026337576 @default.
- W2783500575 hasAuthorship W2783500575A5037230392 @default.
- W2783500575 hasAuthorship W2783500575A5050892378 @default.
- W2783500575 hasAuthorship W2783500575A5069889138 @default.
- W2783500575 hasAuthorship W2783500575A5072912292 @default.
- W2783500575 hasConcept C112705442 @default.
- W2783500575 hasConcept C126322002 @default.
- W2783500575 hasConcept C126894567 @default.
- W2783500575 hasConcept C139254425 @default.
- W2783500575 hasConcept C159641895 @default.
- W2783500575 hasConcept C178790620 @default.
- W2783500575 hasConcept C185592680 @default.
- W2783500575 hasConcept C2776183862 @default.
- W2783500575 hasConcept C2776492347 @default.
- W2783500575 hasConcept C2778789114 @default.
- W2783500575 hasConcept C42219234 @default.
- W2783500575 hasConcept C43376680 @default.
- W2783500575 hasConcept C543218039 @default.
- W2783500575 hasConcept C71924100 @default.
- W2783500575 hasConcept C77411442 @default.
- W2783500575 hasConceptScore W2783500575C112705442 @default.
- W2783500575 hasConceptScore W2783500575C126322002 @default.
- W2783500575 hasConceptScore W2783500575C126894567 @default.
- W2783500575 hasConceptScore W2783500575C139254425 @default.
- W2783500575 hasConceptScore W2783500575C159641895 @default.
- W2783500575 hasConceptScore W2783500575C178790620 @default.
- W2783500575 hasConceptScore W2783500575C185592680 @default.
- W2783500575 hasConceptScore W2783500575C2776183862 @default.
- W2783500575 hasConceptScore W2783500575C2776492347 @default.
- W2783500575 hasConceptScore W2783500575C2778789114 @default.
- W2783500575 hasConceptScore W2783500575C42219234 @default.
- W2783500575 hasConceptScore W2783500575C43376680 @default.
- W2783500575 hasConceptScore W2783500575C543218039 @default.
- W2783500575 hasConceptScore W2783500575C71924100 @default.
- W2783500575 hasConceptScore W2783500575C77411442 @default.
- W2783500575 hasLocation W27835005751 @default.
- W2783500575 hasLocation W27835005752 @default.
- W2783500575 hasOpenAccess W2783500575 @default.
- W2783500575 hasPrimaryLocation W27835005751 @default.
- W2783500575 hasRelatedWork W1842450509 @default.
- W2783500575 hasRelatedWork W1989496610 @default.
- W2783500575 hasRelatedWork W2064093967 @default.
- W2783500575 hasRelatedWork W2733211396 @default.
- W2783500575 hasRelatedWork W2945458105 @default.
- W2783500575 hasRelatedWork W3036958548 @default.
- W2783500575 hasRelatedWork W3082780834 @default.
- W2783500575 hasRelatedWork W3174664513 @default.
- W2783500575 hasRelatedWork W3201505664 @default.
- W2783500575 hasRelatedWork W4213413509 @default.
- W2783500575 hasVolume "44" @default.
- W2783500575 isParatext "false" @default.
- W2783500575 isRetracted "false" @default.
- W2783500575 magId "2783500575" @default.
- W2783500575 workType "article" @default.