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• W2799400560 endingPage "237" @default.
• W2799400560 startingPage "237" @default.
• W2799400560 abstract "Asthma is a chronic disease that is caused by airway inflammation. The main features of asthma are airway hyperresponsiveness (AHR) and reversible airway obstruction. The disease is mainly managed using drug therapy. The current asthma drug treatments are divided into two categories, namely, anti-inflammatory drugs and bronchodilators. However, disease control in asthma patients is not very efficient because the pathogenesis of asthma is complicated, inducing factors that are varied, such as the differences between individual patients. In this paper, we delineate the genetic mechanisms of asthma, and present asthma-susceptible genes and genetic pharmacology in an attempt to find a diagnosis, early prevention, and treatment methods for asthma. Finally, we reposition some clinical drugs for asthma therapy, based on asthma genetics." @default.
• W2799400560 created "2018-05-17" @default.
• W2799400560 creator A5047689706 @default.
• W2799400560 creator A5058691896 @default.
• W2799400560 date "2018-05-03" @default.
• W2799400560 modified "2023-10-02" @default.
• W2799400560 title "Genetic Mechanisms of Asthma and the Implications for Drug Repositioning" @default.
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