FRINK Linked Data Fragments server

Matches in SemOpenAlex for { <https://semopenalex.org/work/W2885320596> ?p ?o ?g. }

• W2885320596 endingPage "24" @default.
• W2885320596 startingPage "18" @default.
• W2885320596 abstract "Background and purpose The great majority of patients with lateralized head and neck squamous cell carcinoma (HNSCC) treated with radiotherapy routinely undergo bilateral elective nodal irradiation (ENI), even though the incidence of contralateral regional failure after unilateral ENI is low. Excluding the contralateral neck from elective irradiation could reduce radiation-related toxicity and improve quality-of-life. The current study investigated the dosimetric benefits of a novel approach using lymph drainage mapping by SPECT/CT to select patients for unilateral ENI. Patients and methods Forty patients with lateralized cT1-3N0-2bM0 HNSCC underwent lymph drainage mapping. Two radiation plans were made; the real plan with which patients were actually treated (selective SPECT/CT-guided plan irradiating the ipsilateral neck ± any contralateral draining level); and the virtual plan (standard plan according to institutional guidelines, as if the same patient would have been treated bilaterally). Radiation doses to clinically important organs-at-risk were compared between the two plans. We used five normal tissue complication probability (NTCP) models to predict the clinical benefits of this approach. Results Median dose reductions to the contralateral parotid gland, contralateral submandibular gland, glottic larynx, supraglottic larynx, constrictor muscle and thyroid gland were 19.2, 27.3, 11.4, 9.7, 12.1 and 18.4 Gy, respectively. Median NTCP reductions for xerostomia, contralateral parotid function, dysphagia, hypothyroidism and laryngeal edema were 20%, 14%, 10%, 20% and 5% respectively. Conclusions Selective SPECT/CT-guided ENI results in significant dose reductions to various organs-at-risk and corresponding NTCP values, and will subsequently reduce the incidence and severity of different troublesome radiation-related toxicities and improve quality-of-life." @default.
• W2885320596 created "2018-08-22" @default.
• W2885320596 creator A5024540647 @default.
• W2885320596 creator A5027012956 @default.
• W2885320596 creator A5039151410 @default.
• W2885320596 creator A5047919769 @default.
• W2885320596 creator A5064324065 @default.
• W2885320596 creator A5080758695 @default.
• W2885320596 creator A5080806192 @default.
• W2885320596 creator A5087851185 @default.
• W2885320596 date "2019-01-01" @default.
• W2885320596 modified "2023-10-02" @default.
• W2885320596 title "SPECT/CT-guided elective nodal irradiation for head and neck cancer: Estimation of clinical benefits using NTCP models" @default.
• W2885320596 cites W1770016528 @default.
• W2885320596 cites W1872443540 @default.
• W2885320596 cites W1971159425 @default.
• W2885320596 cites W1986093144 @default.
• W2885320596 cites W1986565583 @default.
• W2885320596 cites W1989207107 @default.
• W2885320596 cites W1994747484 @default.
• W2885320596 cites W2022694432 @default.
• W2885320596 cites W2057691621 @default.
• W2885320596 cites W2057983723 @default.
• W2885320596 cites W2068155034 @default.
• W2885320596 cites W2081365004 @default.
• W2885320596 cites W2087284528 @default.
• W2885320596 cites W2091940655 @default.
• W2885320596 cites W2102907744 @default.
• W2885320596 cites W2104783586 @default.
• W2885320596 cites W2112884386 @default.
• W2885320596 cites W2113210661 @default.
• W2885320596 cites W2136716437 @default.
• W2885320596 cites W2140110477 @default.
• W2885320596 cites W2143680521 @default.
• W2885320596 cites W2147397709 @default.
• W2885320596 cites W2148754315 @default.
• W2885320596 cites W2152481243 @default.
• W2885320596 cites W2166005406 @default.
• W2885320596 cites W2169496348 @default.
• W2885320596 cites W2214035636 @default.
• W2885320596 cites W2218869932 @default.
• W2885320596 cites W2645116524 @default.
• W2885320596 cites W2810893991 @default.
• W2885320596 cites W4233026002 @default.
• W2885320596 cites W4242885019 @default.
• W2885320596 doi "https://doi.org/10.1016/j.radonc.2018.07.023" @default.
• W2885320596 hasPubMedId "https://pubmed.ncbi.nlm.nih.gov/30087057" @default.
• W2885320596 hasPublicationYear "2019" @default.
• W2885320596 type Work @default.
• W2885320596 sameAs 2885320596 @default.
• W2885320596 citedByCount "16" @default.
• W2885320596 countsByYear W28853205962019 @default.
• W2885320596 countsByYear W28853205962020 @default.
• W2885320596 countsByYear W28853205962021 @default.
• W2885320596 countsByYear W28853205962022 @default.
• W2885320596 countsByYear W28853205962023 @default.
• W2885320596 crossrefType "journal-article" @default.
• W2885320596 hasAuthorship W2885320596A5024540647 @default.
• W2885320596 hasAuthorship W2885320596A5027012956 @default.
• W2885320596 hasAuthorship W2885320596A5039151410 @default.
• W2885320596 hasAuthorship W2885320596A5047919769 @default.
• W2885320596 hasAuthorship W2885320596A5064324065 @default.
• W2885320596 hasAuthorship W2885320596A5080758695 @default.
• W2885320596 hasAuthorship W2885320596A5080806192 @default.
• W2885320596 hasAuthorship W2885320596A5087851185 @default.
• W2885320596 hasBestOaLocation W28853205962 @default.
• W2885320596 hasConcept C126838900 @default.
• W2885320596 hasConcept C141071460 @default.
• W2885320596 hasConcept C142724271 @default.
• W2885320596 hasConcept C2776530083 @default.
• W2885320596 hasConcept C2776833033 @default.
• W2885320596 hasConcept C2780395140 @default.
• W2885320596 hasConcept C2780474809 @default.
• W2885320596 hasConcept C2780596822 @default.
• W2885320596 hasConcept C2780886150 @default.
• W2885320596 hasConcept C2910317908 @default.
• W2885320596 hasConcept C2989005 @default.
• W2885320596 hasConcept C509974204 @default.
• W2885320596 hasConcept C71924100 @default.
• W2885320596 hasConceptScore W2885320596C126838900 @default.
• W2885320596 hasConceptScore W2885320596C141071460 @default.
• W2885320596 hasConceptScore W2885320596C142724271 @default.
• W2885320596 hasConceptScore W2885320596C2776530083 @default.
• W2885320596 hasConceptScore W2885320596C2776833033 @default.
• W2885320596 hasConceptScore W2885320596C2780395140 @default.
• W2885320596 hasConceptScore W2885320596C2780474809 @default.
• W2885320596 hasConceptScore W2885320596C2780596822 @default.
• W2885320596 hasConceptScore W2885320596C2780886150 @default.
• W2885320596 hasConceptScore W2885320596C2910317908 @default.
• W2885320596 hasConceptScore W2885320596C2989005 @default.
• W2885320596 hasConceptScore W2885320596C509974204 @default.
• W2885320596 hasConceptScore W2885320596C71924100 @default.
• W2885320596 hasLocation W28853205961 @default.
• W2885320596 hasLocation W28853205962 @default.
• W2885320596 hasLocation W28853205963 @default.
• W2885320596 hasLocation W28853205964 @default.
• W2885320596 hasOpenAccess W2885320596 @default.
• W2885320596 hasPrimaryLocation W28853205961 @default.

• next