FRINK Linked Data Fragments server

Matches in SemOpenAlex for { <https://semopenalex.org/work/W2890874975> ?p ?o ?g. }

• W2890874975 endingPage "491" @default.
• W2890874975 startingPage "481" @default.
• W2890874975 abstract "Platelets are major sources of microparticles (MPs) in peripheral bloodstream, and platelet-secreted MPs (P-MPs) transfer biological information to neighboring cells. In the present study, we found that the platelet- and P-MPs-derived microRNA-4306 (miR-4306) expression were downregulated in coronary artery disease (CAD) and platelet-derived miR-4306 was an independent poor prognostic factor in CAD. Plasma miRNA-4306 mainly cofractionated with MPs instead of Argonaute2 complexes or HDL. P-MPs could effectively deliver miR-4306 into human monocyte-derived macrophages (HMDMs). MiR-4306 noticeably inhibited the HMDMs migration in vitro and reduced the number of macrophage cells in cardiac tissue in myocardial infarction mice. This functional impact of miR-4306 was mediated directly through VEGFA to inhibit ERK/NF-κB signaling. In conclusion, our study suggested that intercellular transfer of miR-4306 by platelet microparticles inhibited the HMDMs migration through VEGFA/ERK1/2/NF-κB signaling pathways." @default.
• W2890874975 created "2018-09-27" @default.
• W2890874975 creator A5002262271 @default.
• W2890874975 creator A5006735049 @default.
• W2890874975 creator A5008232261 @default.
• W2890874975 creator A5016366257 @default.
• W2890874975 creator A5016899204 @default.
• W2890874975 creator A5019646627 @default.
• W2890874975 creator A5023538996 @default.
• W2890874975 creator A5041111707 @default.
• W2890874975 creator A5062681526 @default.
• W2890874975 creator A5065036137 @default.
• W2890874975 date "2018-09-05" @default.
• W2890874975 modified "2023-09-27" @default.
• W2890874975 title "Platelet microparticles-containing miR-4306 inhibits human monocyte-derived macrophages migration through VEGFA/ERK1/2/NF-κB signaling pathways" @default.
• W2890874975 cites W1851482197 @default.
• W2890874975 cites W1914708428 @default.
• W2890874975 cites W1935158033 @default.
• W2890874975 cites W1965147416 @default.
• W2890874975 cites W2024206172 @default.
• W2890874975 cites W2030712838 @default.
• W2890874975 cites W2032696674 @default.
• W2890874975 cites W2075559361 @default.
• W2890874975 cites W2092693006 @default.
• W2890874975 cites W2092869288 @default.
• W2890874975 cites W2112187582 @default.
• W2890874975 cites W2126601545 @default.
• W2890874975 cites W2139350557 @default.
• W2890874975 cites W2155688961 @default.
• W2890874975 cites W2161068194 @default.
• W2890874975 cites W2169403180 @default.
• W2890874975 cites W2194131658 @default.
• W2890874975 cites W2586038252 @default.
• W2890874975 cites W301388723 @default.
• W2890874975 doi "https://doi.org/10.1080/10641963.2018.1510941" @default.
• W2890874975 hasPubMedId "https://pubmed.ncbi.nlm.nih.gov/30183452" @default.
• W2890874975 hasPublicationYear "2018" @default.
• W2890874975 type Work @default.
• W2890874975 sameAs 2890874975 @default.
• W2890874975 citedByCount "17" @default.
• W2890874975 countsByYear W28908749752019 @default.
• W2890874975 countsByYear W28908749752020 @default.
• W2890874975 countsByYear W28908749752021 @default.
• W2890874975 countsByYear W28908749752022 @default.
• W2890874975 countsByYear W28908749752023 @default.
• W2890874975 crossrefType "journal-article" @default.
• W2890874975 hasAuthorship W2890874975A5002262271 @default.
• W2890874975 hasAuthorship W2890874975A5006735049 @default.
• W2890874975 hasAuthorship W2890874975A5008232261 @default.
• W2890874975 hasAuthorship W2890874975A5016366257 @default.
• W2890874975 hasAuthorship W2890874975A5016899204 @default.
• W2890874975 hasAuthorship W2890874975A5019646627 @default.
• W2890874975 hasAuthorship W2890874975A5023538996 @default.
• W2890874975 hasAuthorship W2890874975A5041111707 @default.
• W2890874975 hasAuthorship W2890874975A5062681526 @default.
• W2890874975 hasAuthorship W2890874975A5065036137 @default.
• W2890874975 hasConcept C126322002 @default.
• W2890874975 hasConcept C164027704 @default.
• W2890874975 hasConcept C186738567 @default.
• W2890874975 hasConcept C203014093 @default.
• W2890874975 hasConcept C2776914184 @default.
• W2890874975 hasConcept C2777730290 @default.
• W2890874975 hasConcept C2778382381 @default.
• W2890874975 hasConcept C2781184567 @default.
• W2890874975 hasConcept C502942594 @default.
• W2890874975 hasConcept C62478195 @default.
• W2890874975 hasConcept C71924100 @default.
• W2890874975 hasConcept C86803240 @default.
• W2890874975 hasConcept C89560881 @default.
• W2890874975 hasConcept C95444343 @default.
• W2890874975 hasConceptScore W2890874975C126322002 @default.
• W2890874975 hasConceptScore W2890874975C164027704 @default.
• W2890874975 hasConceptScore W2890874975C186738567 @default.
• W2890874975 hasConceptScore W2890874975C203014093 @default.
• W2890874975 hasConceptScore W2890874975C2776914184 @default.
• W2890874975 hasConceptScore W2890874975C2777730290 @default.
• W2890874975 hasConceptScore W2890874975C2778382381 @default.
• W2890874975 hasConceptScore W2890874975C2781184567 @default.
• W2890874975 hasConceptScore W2890874975C502942594 @default.
• W2890874975 hasConceptScore W2890874975C62478195 @default.
• W2890874975 hasConceptScore W2890874975C71924100 @default.
• W2890874975 hasConceptScore W2890874975C86803240 @default.
• W2890874975 hasConceptScore W2890874975C89560881 @default.
• W2890874975 hasConceptScore W2890874975C95444343 @default.
• W2890874975 hasIssue "5" @default.
• W2890874975 hasLocation W28908749751 @default.
• W2890874975 hasLocation W28908749752 @default.
• W2890874975 hasOpenAccess W2890874975 @default.
• W2890874975 hasPrimaryLocation W28908749751 @default.
• W2890874975 hasRelatedWork W1665208458 @default.
• W2890874975 hasRelatedWork W2002912878 @default.
• W2890874975 hasRelatedWork W2003687326 @default.
• W2890874975 hasRelatedWork W2088547254 @default.
• W2890874975 hasRelatedWork W2099224019 @default.
• W2890874975 hasRelatedWork W2139505057 @default.
• W2890874975 hasRelatedWork W2272326019 @default.
• W2890874975 hasRelatedWork W23057823 @default.
• W2890874975 hasRelatedWork W2365541820 @default.

• next