Matches in SemOpenAlex for { <https://semopenalex.org/work/W2904996690> ?p ?o ?g. }
- W2904996690 endingPage "769" @default.
- W2904996690 startingPage "761" @default.
- W2904996690 abstract "Background The purpose of this study was to evaluate the influence of sex and race/ethnicity upon prevalence trends of human papillomavirus (HPV) in oropharyngeal cancer (OPC) and survival after OPC. Method This was a cohort study of patients included in the United States National Cancer Database who had been diagnosed with OPC between 2010 and 2015. Outcomes were HPV status of tumor specimens and overall survival. Sex‐ and race‐stratified trends in HPV prevalence were estimated using generalized linear modeling. The influence of sex, race, and HPV tumor status on overall survival was compared by Kaplan‐Meier method and Cox Proportional Hazards models. Results This analysis included 20,886 HPV‐positive and 10,364 HPV‐negative OPC patients. The prevalence of HPV‐positive tumors was higher among men (70.6%) than women (56.3%) and increased significantly over time at a rate of 3.5% and 3.2% per year among men and women, respectively. The prevalence of HPV‐positive tumors was highest among whites (70.2%), followed by Hispanics (61.3%), Asians (55.8%), and blacks (46.3%). Blacks and Hispanics experienced significantly more rapid increases in prevalence of HPV‐positive tumors over time compared with whites (6.5% vs 5.6% vs 3.2% per year, respectively). In HPV‐positive OPC, neither sex nor race/ethnicity was associated with survival among patients with HPV‐positive OPC. In contrast, for HPV‐negative OPC, risk of death was significantly higher for women versus men (adjusted hazard ratio [aHR], 1.17; 95% confidence interval [CI], 1.08‐1.26) and blacks versus whites (aHR, 1.21; 95% CI, 1.10‐1.33). Conclusion The prevalence of HPV‐positive tumors is increasing for all sex and race/ethnicity groups in the United States. Sex and race are independently associated with survival for HPV‐negative but not HPV‐positive OPC." @default.
- W2904996690 created "2018-12-22" @default.
- W2904996690 creator A5002679236 @default.
- W2904996690 creator A5045141303 @default.
- W2904996690 creator A5046621722 @default.
- W2904996690 creator A5049371053 @default.
- W2904996690 creator A5051719417 @default.
- W2904996690 creator A5062182044 @default.
- W2904996690 creator A5066909750 @default.
- W2904996690 date "2018-12-06" @default.
- W2904996690 modified "2023-10-16" @default.
- W2904996690 title "The prevalence of human papillomavirus in oropharyngeal cancer is increasing regardless of sex or race, and the influence of sex and race on survival is modified by human papillomavirus tumor status" @default.
- W2904996690 cites W1757407923 @default.
- W2904996690 cites W1975146323 @default.
- W2904996690 cites W2002362032 @default.
- W2904996690 cites W2004079062 @default.
- W2904996690 cites W2009925718 @default.
- W2904996690 cites W2018324554 @default.
- W2904996690 cites W2020830322 @default.
- W2904996690 cites W2026803043 @default.
- W2904996690 cites W2096796899 @default.
- W2904996690 cites W2099281944 @default.
- W2904996690 cites W2107283868 @default.
- W2904996690 cites W2108407785 @default.
- W2904996690 cites W2110664940 @default.
- W2904996690 cites W2123526038 @default.
- W2904996690 cites W2124294874 @default.
- W2904996690 cites W2127605299 @default.
- W2904996690 cites W2128428788 @default.
- W2904996690 cites W2132239791 @default.
- W2904996690 cites W2133183695 @default.
- W2904996690 cites W2138271749 @default.
- W2904996690 cites W2143680521 @default.
- W2904996690 cites W2151269016 @default.
- W2904996690 cites W2156065723 @default.
- W2904996690 cites W2163019733 @default.
- W2904996690 cites W2164710273 @default.
- W2904996690 cites W2165279145 @default.
- W2904996690 cites W2167138865 @default.
- W2904996690 cites W2295744790 @default.
- W2904996690 cites W2578626137 @default.
- W2904996690 cites W2591834340 @default.
- W2904996690 cites W2736395682 @default.
- W2904996690 cites W2750387569 @default.
- W2904996690 cites W2791296718 @default.
- W2904996690 cites W2792941270 @default.
- W2904996690 cites W4206381490 @default.
- W2904996690 cites W66239897 @default.
- W2904996690 doi "https://doi.org/10.1002/cncr.31841" @default.
- W2904996690 hasPubMedId "https://pubmed.ncbi.nlm.nih.gov/30521092" @default.
- W2904996690 hasPublicationYear "2018" @default.
- W2904996690 type Work @default.
- W2904996690 sameAs 2904996690 @default.
- W2904996690 citedByCount "58" @default.
- W2904996690 countsByYear W29049966902019 @default.
- W2904996690 countsByYear W29049966902020 @default.
- W2904996690 countsByYear W29049966902021 @default.
- W2904996690 countsByYear W29049966902022 @default.
- W2904996690 countsByYear W29049966902023 @default.
- W2904996690 crossrefType "journal-article" @default.
- W2904996690 hasAuthorship W2904996690A5002679236 @default.
- W2904996690 hasAuthorship W2904996690A5045141303 @default.
- W2904996690 hasAuthorship W2904996690A5046621722 @default.
- W2904996690 hasAuthorship W2904996690A5049371053 @default.
- W2904996690 hasAuthorship W2904996690A5051719417 @default.
- W2904996690 hasAuthorship W2904996690A5062182044 @default.
- W2904996690 hasAuthorship W2904996690A5066909750 @default.
- W2904996690 hasBestOaLocation W29049966901 @default.
- W2904996690 hasConcept C121608353 @default.
- W2904996690 hasConcept C126322002 @default.
- W2904996690 hasConcept C143998085 @default.
- W2904996690 hasConcept C144024400 @default.
- W2904996690 hasConcept C149923435 @default.
- W2904996690 hasConcept C207103383 @default.
- W2904996690 hasConcept C2778220009 @default.
- W2904996690 hasConcept C2778580637 @default.
- W2904996690 hasConcept C29456083 @default.
- W2904996690 hasConcept C2994532551 @default.
- W2904996690 hasConcept C44249647 @default.
- W2904996690 hasConcept C50382708 @default.
- W2904996690 hasConcept C71924100 @default.
- W2904996690 hasConcept C72563966 @default.
- W2904996690 hasConceptScore W2904996690C121608353 @default.
- W2904996690 hasConceptScore W2904996690C126322002 @default.
- W2904996690 hasConceptScore W2904996690C143998085 @default.
- W2904996690 hasConceptScore W2904996690C144024400 @default.
- W2904996690 hasConceptScore W2904996690C149923435 @default.
- W2904996690 hasConceptScore W2904996690C207103383 @default.
- W2904996690 hasConceptScore W2904996690C2778220009 @default.
- W2904996690 hasConceptScore W2904996690C2778580637 @default.
- W2904996690 hasConceptScore W2904996690C29456083 @default.
- W2904996690 hasConceptScore W2904996690C2994532551 @default.
- W2904996690 hasConceptScore W2904996690C44249647 @default.
- W2904996690 hasConceptScore W2904996690C50382708 @default.
- W2904996690 hasConceptScore W2904996690C71924100 @default.
- W2904996690 hasConceptScore W2904996690C72563966 @default.
- W2904996690 hasIssue "5" @default.
- W2904996690 hasLocation W29049966901 @default.