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- W2912470627 abstract "SUMMARY Background Autoimmune hepatitis ( AIH ) is a chronic inflammatory liver disease that results in substantial morbidity and mortality with many unanswered clinical and research questions. Improved understanding of disease pathogenesis, including the extra‐hepatic manifestations of AIH, may allow targeted treatments with greater efficacy and fewer associated adverse events. Aim To identify the spectrum of unanswered clinical and research questions facing care providers in the management of patients with autoimmune hepatitis ( AIH ). Methods The International Autoimmune Hepatitis Group initiated a series of research workshops to start to address these questions. Key issues were discussed in small group sessions with collation of all discussions to be summarised in this manuscript. Results Key issues were identified as: the need for better understanding of disease pathogenesis, standardisation of the methods and assays used to evaluate autoantibodies in AIH, refinement of the histopathological criteria for “typical” or “compatible” AIH, focus on the interaction with non‐alcohol related fatty liver disease, how to treat acute severe AIH, better assessment of quality of life in adults and paediatrics, standardising use of standard, third‐line and experimental therapies in AIH and search for biomarkers early in the disease course that predict outcome. Conclusion This workshop has outlined the key unanswered clinical and research questions to help to define the research agenda in AIH." @default.
- W2912470627 created "2019-02-21" @default.
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- W2912470627 date "2019-01-22" @default.
- W2912470627 modified "2023-10-12" @default.
- W2912470627 title "Review article: unanswered clinical and research questions in autoimmune hepatitis-conclusions of the International Autoimmune Hepatitis Group Research Workshop" @default.
- W2912470627 cites W116289366 @default.
- W2912470627 cites W1498948971 @default.
- W2912470627 cites W1506900878 @default.
- W2912470627 cites W1507163675 @default.
- W2912470627 cites W1518177083 @default.
- W2912470627 cites W1557551939 @default.
- W2912470627 cites W1576969247 @default.
- W2912470627 cites W1597600359 @default.
- W2912470627 cites W1615256381 @default.
- W2912470627 cites W1894277271 @default.
- W2912470627 cites W1972531935 @default.
- W2912470627 cites W1973130325 @default.
- W2912470627 cites W1981732955 @default.
- W2912470627 cites W1983398005 @default.
- W2912470627 cites W1985748383 @default.
- W2912470627 cites W1986337007 @default.
- W2912470627 cites W1987356042 @default.
- W2912470627 cites W1994532961 @default.
- W2912470627 cites W2000484633 @default.
- W2912470627 cites W2000959749 @default.
- W2912470627 cites W2008811593 @default.
- W2912470627 cites W2017685297 @default.
- W2912470627 cites W2017821181 @default.
- W2912470627 cites W2019850008 @default.
- W2912470627 cites W2020950635 @default.
- W2912470627 cites W2024645140 @default.
- W2912470627 cites W2037872763 @default.
- W2912470627 cites W2039576552 @default.
- W2912470627 cites W2042321442 @default.
- W2912470627 cites W2044963057 @default.
- W2912470627 cites W2045127102 @default.
- W2912470627 cites W2049470465 @default.
- W2912470627 cites W2051032344 @default.
- W2912470627 cites W2055960007 @default.
- W2912470627 cites W2068123329 @default.
- W2912470627 cites W2071553791 @default.
- W2912470627 cites W2072296219 @default.
- W2912470627 cites W2080908224 @default.
- W2912470627 cites W2083171998 @default.
- W2912470627 cites W2085106134 @default.
- W2912470627 cites W2086771055 @default.
- W2912470627 cites W2092696659 @default.
- W2912470627 cites W2094245034 @default.
- W2912470627 cites W2095937258 @default.
- W2912470627 cites W2104790602 @default.
- W2912470627 cites W2113333488 @default.
- W2912470627 cites W2118422146 @default.
- W2912470627 cites W2128062619 @default.
- W2912470627 cites W2132205159 @default.
- W2912470627 cites W2135623413 @default.
- W2912470627 cites W2141948375 @default.
- W2912470627 cites W2145649264 @default.
- W2912470627 cites W2149742106 @default.
- W2912470627 cites W2152242693 @default.
- W2912470627 cites W2153604428 @default.
- W2912470627 cites W2156101594 @default.
- W2912470627 cites W2160126419 @default.
- W2912470627 cites W2165399346 @default.
- W2912470627 cites W2166497420 @default.
- W2912470627 cites W2166653283 @default.
- W2912470627 cites W2167776875 @default.
- W2912470627 cites W2173141813 @default.
- W2912470627 cites W2175148789 @default.
- W2912470627 cites W2236935008 @default.
- W2912470627 cites W2270554445 @default.
- W2912470627 cites W2285144131 @default.
- W2912470627 cites W2288573834 @default.
- W2912470627 cites W2296539228 @default.
- W2912470627 cites W2318016411 @default.
- W2912470627 cites W2328996992 @default.
- W2912470627 cites W2331543379 @default.
- W2912470627 cites W2344404994 @default.
- W2912470627 cites W2346647999 @default.
- W2912470627 cites W2417077670 @default.
- W2912470627 cites W2489335229 @default.
- W2912470627 cites W2491165534 @default.
- W2912470627 cites W2514392790 @default.
- W2912470627 cites W2560715193 @default.
- W2912470627 cites W2565864958 @default.
- W2912470627 cites W2579289641 @default.
- W2912470627 cites W2590262026 @default.