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- W2912761378 abstract "Purpose: Inflammatory Bowel Disease (IBD) is a lifelong condition that often requires multiple medications to treat flares of disease activity and to maintain remission. The aim of this study was to investigate if a patient's disease severity and duration influenced his or her choice of medical or surgical treatment preferences, in order to better prescribe appropriate medication for maximizing compliance. Methods: A comprehensive questionnaire was administered to 50 consecutive patients with a known diagnosis of IBD, visiting the Yale IBD clinic from July to November 2006. The questionnaire included demographics, disease and medication history, questions on preferences of medication types (5-aminosalicylic acid agents (5ASA), enemas, oral steroids, immunosuppressants, anti TNF agents and surgery) with reasons. The patients were divided into 2 groups based on their disease severity-mild (1–4 bowel movements/day, no urgency, rare blood, mild pain) and moderate/severe (>5 bowel movements/day with blood, urgency and interference with daily activities). The same set of patients were also divided into 2 groups based on disease duration (DD)-≤10 years and >10 years. Results: The questionnaire was completed by 50 patients (33 with CD and 17 with UC). The patients comprised 28 females and 22 males with a mean age of 41.52(± 15) years and mean disease duration of 8.8(± 9.6) years. Treatment preferences of the different groups are as follows: Majority of the patients preferred 5ASA due to its efficacy and milder side effect profile. Surgery was the least preferred treatment modality due to side effects and cost, followed by steroids due to their side effects. Conclusion: In our preliminary report, disease severity appeared to influence the choice of preferred medication, with moderate to severe disease patients preferring more aggressive treatment modality like anti TNF agents equally to 5ASA. Patients with any disease severity unanimously chose surgery as the least preferred treatment. Disease duration did not affect the preferred medication with 5ASA being the top choice of treatment, but patients with shorter disease duration did not prefer oral steroids equally to surgery." @default.
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- W2912761378 date "2007-09-01" @default.
- W2912761378 modified "2023-10-14" @default.
- W2912761378 title "Influence of Disease Duration and Severity on Inflammatory Bowel Disease Patients’ Medication Preference" @default.
- W2912761378 doi "https://doi.org/10.14309/00000434-200709002-00989" @default.
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