Matches in SemOpenAlex for { <https://semopenalex.org/work/W2952061881> ?p ?o ?g. }
Showing items 1 to 71 of
71
with 100 items per page.
- W2952061881 endingPage "614" @default.
- W2952061881 startingPage "607" @default.
- W2952061881 abstract "Bacground/Aim. Treatment of neurological diseases usually requires polypharmacy, and it is crucial to detect potential drug-drug interactions (DDIs) and recognize risk factors on time, as consequences of DDIs could be serious. The aim of the study was to analyze risk factors for the occurrence and the number of potential DDIs among patients in a general neurological ward. Methods. This study was conducted with 144 inpatients in a general-care neurological department of a tertiary care hospital. The effects of risk factors for potential DDIs were evaluated by multiple linear regression. The study had retrospective cohort de-sign. Frequencies of various types of potential DDIs (according to severity) were discovered by Medscape, Epocrates and Micromedex online interaction checkers. Results. The number of prescribed drugs, age of a patient, value of the Charlson comorbidity index and prescription of an antidepressant increase risk of potential DDIs in a general neurology ward. On the other hand, being paralyzed, number of prescribers for a single patient, being bedridden for at least one day of hospitalization decreased the number of potential DDIs per patient. Number of prescribed drugs per patient [odds ratio (OR) = 1.466 ? 0.250; p = 0.000) and age (OR = 1.027 ? 0.026; p = 0.041)] increased, and number of prescribers per patient (OR = 0.056 ? 0.028; p = 0.016), especially if the patients were paralyzed (OR = 0.214 ? 0.294; p = 0.007), decreased the risk of contraindicated, serious, ?use alternative? or major potential DDIs. Antidepressants increased the risk of absolute number of all monitor/modify potential DDIs (OR = 1.257 ? 0.726; p = 0.035). Conclusion. Frequency of potential DDIs among neurological patients is considerable and influenced to the largest extent by advanced age, comorbidities, total number of pre-scribed drugs per patient and concomitant use of antidepressants." @default.
- W2952061881 created "2019-06-27" @default.
- W2952061881 creator A5018698921 @default.
- W2952061881 creator A5037796210 @default.
- W2952061881 creator A5087367073 @default.
- W2952061881 date "2021-01-01" @default.
- W2952061881 modified "2023-10-16" @default.
- W2952061881 title "Risk factors for potential drug-drug interactions in a general neurology ward" @default.
- W2952061881 doi "https://doi.org/10.2298/vsp190401105k" @default.
- W2952061881 hasPublicationYear "2021" @default.
- W2952061881 type Work @default.
- W2952061881 sameAs 2952061881 @default.
- W2952061881 citedByCount "0" @default.
- W2952061881 crossrefType "journal-article" @default.
- W2952061881 hasAuthorship W2952061881A5018698921 @default.
- W2952061881 hasAuthorship W2952061881A5037796210 @default.
- W2952061881 hasAuthorship W2952061881A5087367073 @default.
- W2952061881 hasBestOaLocation W29520618811 @default.
- W2952061881 hasConcept C118552586 @default.
- W2952061881 hasConcept C126322002 @default.
- W2952061881 hasConcept C151956035 @default.
- W2952061881 hasConcept C156957248 @default.
- W2952061881 hasConcept C16568411 @default.
- W2952061881 hasConcept C167135981 @default.
- W2952061881 hasConcept C177713679 @default.
- W2952061881 hasConcept C194828623 @default.
- W2952061881 hasConcept C2426938 @default.
- W2952061881 hasConcept C2779159551 @default.
- W2952061881 hasConcept C2780035454 @default.
- W2952061881 hasConcept C36434225 @default.
- W2952061881 hasConcept C71924100 @default.
- W2952061881 hasConcept C72563966 @default.
- W2952061881 hasConcept C98274493 @default.
- W2952061881 hasConceptScore W2952061881C118552586 @default.
- W2952061881 hasConceptScore W2952061881C126322002 @default.
- W2952061881 hasConceptScore W2952061881C151956035 @default.
- W2952061881 hasConceptScore W2952061881C156957248 @default.
- W2952061881 hasConceptScore W2952061881C16568411 @default.
- W2952061881 hasConceptScore W2952061881C167135981 @default.
- W2952061881 hasConceptScore W2952061881C177713679 @default.
- W2952061881 hasConceptScore W2952061881C194828623 @default.
- W2952061881 hasConceptScore W2952061881C2426938 @default.
- W2952061881 hasConceptScore W2952061881C2779159551 @default.
- W2952061881 hasConceptScore W2952061881C2780035454 @default.
- W2952061881 hasConceptScore W2952061881C36434225 @default.
- W2952061881 hasConceptScore W2952061881C71924100 @default.
- W2952061881 hasConceptScore W2952061881C72563966 @default.
- W2952061881 hasConceptScore W2952061881C98274493 @default.
- W2952061881 hasIssue "6" @default.
- W2952061881 hasLocation W29520618811 @default.
- W2952061881 hasLocation W29520618812 @default.
- W2952061881 hasLocation W29520618813 @default.
- W2952061881 hasOpenAccess W2952061881 @default.
- W2952061881 hasPrimaryLocation W29520618811 @default.
- W2952061881 hasRelatedWork W2165421275 @default.
- W2952061881 hasRelatedWork W2278680866 @default.
- W2952061881 hasRelatedWork W2766956564 @default.
- W2952061881 hasRelatedWork W2940572760 @default.
- W2952061881 hasRelatedWork W3092758552 @default.
- W2952061881 hasRelatedWork W3101929511 @default.
- W2952061881 hasRelatedWork W4200481586 @default.
- W2952061881 hasRelatedWork W4285503037 @default.
- W2952061881 hasRelatedWork W4378472537 @default.
- W2952061881 hasRelatedWork W2149351151 @default.
- W2952061881 hasVolume "78" @default.
- W2952061881 isParatext "false" @default.
- W2952061881 isRetracted "false" @default.
- W2952061881 magId "2952061881" @default.
- W2952061881 workType "article" @default.