FRINK Linked Data Fragments server

Matches in SemOpenAlex for { <https://semopenalex.org/work/W2966314564> ?p ?o ?g. }

• W2966314564 endingPage "804" @default.
• W2966314564 startingPage "800" @default.
• W2966314564 abstract "Aims The clinical significance of radial scar (RS)/complex sclerosing lesion (CSL) with high-risk lesions (epithelial atypia) diagnosed on needle core biopsy is not well defined. We aimed at assessing the upgrade rate to ductal carcinoma in situ (DCIS) and invasive carcinoma on the surgical excision specimen in a large cohort with RS/CSL associated with atypia. Methods 157 women with a needle core biopsy diagnosis of a RS/CSL with atypia and follow-up histology were studied. Histological findings, including different forms of the atypical lesions and final histological outcome in the excision specimens, were retrieved and analysed, and the upgrade rates for malignancy and for invasive carcinoma were calculated. Results 69.43% of the cases were associated with atypical ductal hyperplasia (ADH) or atypia not otherwise classifiable, whereas lobular neoplasia was seen in 21.66%. On final histology, 39 cases were malignant (overall upgrade rate of 24.84%); 12 were invasive and 27 had DCIS. The upgrade differed according to the type of atypia and was highest for ADH (35%). When associated with lobular neoplasia, the upgrade rate was 11.76%. The upgrade rate’s variability was also considerably lower when considering the upgrade to invasive carcinoma alone for any associated lesion. Conclusions The upgrade rate for ADH diagnosed on needle core biopsy with RS is similar to that of ADH without RS and therefore should be managed similarly. RS associated with lobular neoplasia is less frequently associated with malignant outcome. Most lesions exhibiting some degree of atypia showed a similar upgrade rate to invasive carcinoma. Management of RS should be based on the concurrent atypical lesion." @default.
• W2966314564 created "2019-08-13" @default.
• W2966314564 creator A5004074922 @default.
• W2966314564 creator A5012034585 @default.
• W2966314564 creator A5017412677 @default.
• W2966314564 creator A5022455206 @default.
• W2966314564 creator A5028298545 @default.
• W2966314564 creator A5033485831 @default.
• W2966314564 creator A5034519523 @default.
• W2966314564 creator A5044361037 @default.
• W2966314564 creator A5059260100 @default.
• W2966314564 creator A5068484326 @default.
• W2966314564 creator A5080544464 @default.
• W2966314564 creator A5080552040 @default.
• W2966314564 creator A5088553855 @default.
• W2966314564 date "2019-07-26" @default.
• W2966314564 modified "2023-10-04" @default.
• W2966314564 title "Outcome of radial scar/complex sclerosing lesion associated with epithelial proliferations with atypia diagnosed on breast core biopsy: results from a multicentric UK-based study" @default.
• W2966314564 cites W1559966075 @default.
• W2966314564 cites W1973285844 @default.
• W2966314564 cites W1976110870 @default.
• W2966314564 cites W1996450284 @default.
• W2966314564 cites W2005481781 @default.
• W2966314564 cites W2005838914 @default.
• W2966314564 cites W2017734936 @default.
• W2966314564 cites W2060259120 @default.
• W2966314564 cites W2064750973 @default.
• W2966314564 cites W2084272416 @default.
• W2966314564 cites W2085497299 @default.
• W2966314564 cites W2111279904 @default.
• W2966314564 cites W2148309496 @default.
• W2966314564 cites W2163762972 @default.
• W2966314564 cites W2176189385 @default.
• W2966314564 cites W2192552377 @default.
• W2966314564 cites W2252482652 @default.
• W2966314564 cites W2305737469 @default.
• W2966314564 cites W2324328136 @default.
• W2966314564 cites W2470732571 @default.
• W2966314564 cites W2507876483 @default.
• W2966314564 cites W2509949604 @default.
• W2966314564 cites W4211132180 @default.
• W2966314564 doi "https://doi.org/10.1136/jclinpath-2019-205764" @default.
• W2966314564 hasPubMedId "https://pubmed.ncbi.nlm.nih.gov/31350292" @default.
• W2966314564 hasPublicationYear "2019" @default.
• W2966314564 type Work @default.
• W2966314564 sameAs 2966314564 @default.
• W2966314564 citedByCount "12" @default.
• W2966314564 countsByYear W29663145642020 @default.
• W2966314564 countsByYear W29663145642021 @default.
• W2966314564 countsByYear W29663145642022 @default.
• W2966314564 countsByYear W29663145642023 @default.
• W2966314564 crossrefType "journal-article" @default.
• W2966314564 hasAuthorship W2966314564A5004074922 @default.
• W2966314564 hasAuthorship W2966314564A5012034585 @default.
• W2966314564 hasAuthorship W2966314564A5017412677 @default.
• W2966314564 hasAuthorship W2966314564A5022455206 @default.
• W2966314564 hasAuthorship W2966314564A5028298545 @default.
• W2966314564 hasAuthorship W2966314564A5033485831 @default.
• W2966314564 hasAuthorship W2966314564A5034519523 @default.
• W2966314564 hasAuthorship W2966314564A5044361037 @default.
• W2966314564 hasAuthorship W2966314564A5059260100 @default.
• W2966314564 hasAuthorship W2966314564A5068484326 @default.
• W2966314564 hasAuthorship W2966314564A5080544464 @default.
• W2966314564 hasAuthorship W2966314564A5080552040 @default.
• W2966314564 hasAuthorship W2966314564A5088553855 @default.
• W2966314564 hasBestOaLocation W29663145642 @default.
• W2966314564 hasConcept C121608353 @default.
• W2966314564 hasConcept C126322002 @default.
• W2966314564 hasConcept C126838900 @default.
• W2966314564 hasConcept C142724271 @default.
• W2966314564 hasConcept C204232928 @default.
• W2966314564 hasConcept C2775934546 @default.
• W2966314564 hasConcept C2777546739 @default.
• W2966314564 hasConcept C2779296616 @default.
• W2966314564 hasConcept C2779399171 @default.
• W2966314564 hasConcept C2780862961 @default.
• W2966314564 hasConcept C2781156865 @default.
• W2966314564 hasConcept C2781283455 @default.
• W2966314564 hasConcept C2781289014 @default.
• W2966314564 hasConcept C3018521938 @default.
• W2966314564 hasConcept C530470458 @default.
• W2966314564 hasConcept C71924100 @default.
• W2966314564 hasConceptScore W2966314564C121608353 @default.
• W2966314564 hasConceptScore W2966314564C126322002 @default.
• W2966314564 hasConceptScore W2966314564C126838900 @default.
• W2966314564 hasConceptScore W2966314564C142724271 @default.
• W2966314564 hasConceptScore W2966314564C204232928 @default.
• W2966314564 hasConceptScore W2966314564C2775934546 @default.
• W2966314564 hasConceptScore W2966314564C2777546739 @default.
• W2966314564 hasConceptScore W2966314564C2779296616 @default.
• W2966314564 hasConceptScore W2966314564C2779399171 @default.
• W2966314564 hasConceptScore W2966314564C2780862961 @default.
• W2966314564 hasConceptScore W2966314564C2781156865 @default.
• W2966314564 hasConceptScore W2966314564C2781283455 @default.
• W2966314564 hasConceptScore W2966314564C2781289014 @default.
• W2966314564 hasConceptScore W2966314564C3018521938 @default.
• W2966314564 hasConceptScore W2966314564C530470458 @default.
• W2966314564 hasConceptScore W2966314564C71924100 @default.

• next