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- W2999724722 endingPage "104682" @default.
- W2999724722 startingPage "104682" @default.
- W2999724722 abstract "The first issue of Hormones and Behavior was published 50 years ago in 1969, a time when most of the techniques we currently use in Behavioral Endocrinology were not available. Researchers have during the last 5 decades developed techniques that allow measuring hormones in small volumes of biological samples, identify the sites where steroids act in the brain to activate sexual behavior, characterize and quantify gene expression correlated with behavior expression, modify this expression in a specific manner, and manipulate the activity of selected neuronal populations by chemogenetic and optogenetic techniques. This technical progress has considerably transformed the field and has been very beneficial for our understanding of the endocrine controls of behavior in general, but it did also come with some caveats. The facilitation of scientific investigations came with some relaxation of methodological exigency. Some critical controls are no longer performed on a regular basis and complex techniques supplied as ready to use kits are implemented without precise knowledge of their limitations. We present here a selective review of the most important of these new techniques, their potential problems and how they changed our view of the hormonal control of behavior. Fortunately, the scientific endeavor is a self-correcting process. The problems have been identified and corrections have been proposed. The next decades will obviously be filled with exciting discoveries in behavioral neuroendocrinology." @default.
- W2999724722 created "2020-01-23" @default.
- W2999724722 creator A5039368497 @default.
- W2999724722 date "2020-02-01" @default.
- W2999724722 modified "2023-10-14" @default.
- W2999724722 title "How technical progress reshaped behavioral neuroendocrinology during the last 50 years… and some methodological remarks" @default.
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