Matches in SemOpenAlex for { <https://semopenalex.org/work/W3025296939> ?p ?o ?g. }
- W3025296939 endingPage "227" @default.
- W3025296939 startingPage "210" @default.
- W3025296939 abstract "Bone elongation is a complex process driven by multiple intrinsic (hormones, growth factors) and extrinsic (nutrition, environment) variables. Bones grow in length by endochondral ossification in cartilaginous growth plates at ends of developing long bones. This review provides an updated overview of the important factors that influence this process. Insulin-like growth factor-1 (IGF-1) is the major hormone required for growth and a drug for treating pediatric skeletal disorders. Temperature is an underrecognized environmental variable that also impacts linear growth. This paper reviews the current state of knowledge regarding the interaction of IGF-1 and environmental factors on bone elongation. Understanding how internal and external variables regulate bone lengthening is essential for developing and improving treatments for an array of bone elongation disorders. Future studies may benefit from understanding how these unique relationships could offer realistic new approaches for increasing bone length in different growth-limiting conditions." @default.
- W3025296939 created "2020-05-21" @default.
- W3025296939 creator A5020468105 @default.
- W3025296939 creator A5078080035 @default.
- W3025296939 date "2020-05-15" @default.
- W3025296939 modified "2023-10-13" @default.
- W3025296939 title "The Actions of IGF-1 in the Growth Plate and Its Role in Postnatal Bone Elongation" @default.
- W3025296939 cites W1127533971 @default.
- W3025296939 cites W1148869251 @default.
- W3025296939 cites W1217878545 @default.
- W3025296939 cites W141539550 @default.
- W3025296939 cites W1488424161 @default.
- W3025296939 cites W149635714 @default.
- W3025296939 cites W1509427422 @default.
- W3025296939 cites W1517473420 @default.
- W3025296939 cites W15242331 @default.
- W3025296939 cites W1553874512 @default.
- W3025296939 cites W1562028693 @default.
- W3025296939 cites W1562349651 @default.
- W3025296939 cites W1562502661 @default.
- W3025296939 cites W1580329667 @default.
- W3025296939 cites W1583699618 @default.
- W3025296939 cites W1599266856 @default.
- W3025296939 cites W1629149231 @default.
- W3025296939 cites W1798252362 @default.
- W3025296939 cites W1824501739 @default.
- W3025296939 cites W1842429624 @default.
- W3025296939 cites W1853730631 @default.
- W3025296939 cites W1882451129 @default.
- W3025296939 cites W192408054 @default.
- W3025296939 cites W1928450642 @default.
- W3025296939 cites W1931051077 @default.
- W3025296939 cites W1937327178 @default.
- W3025296939 cites W1965867713 @default.
- W3025296939 cites W1966164727 @default.
- W3025296939 cites W1966203527 @default.
- W3025296939 cites W1966687884 @default.
- W3025296939 cites W1968185296 @default.
- W3025296939 cites W1968850244 @default.
- W3025296939 cites W1970341919 @default.
- W3025296939 cites W1971712138 @default.
- W3025296939 cites W1972300771 @default.
- W3025296939 cites W1972454974 @default.
- W3025296939 cites W1973569147 @default.
- W3025296939 cites W1975411570 @default.
- W3025296939 cites W1975520287 @default.
- W3025296939 cites W1978506329 @default.
- W3025296939 cites W1980438710 @default.
- W3025296939 cites W1981976503 @default.
- W3025296939 cites W1982738962 @default.
- W3025296939 cites W1983496424 @default.
- W3025296939 cites W1985109410 @default.
- W3025296939 cites W1985251816 @default.
- W3025296939 cites W1986161955 @default.
- W3025296939 cites W1986436298 @default.
- W3025296939 cites W1989308141 @default.
- W3025296939 cites W1989309809 @default.
- W3025296939 cites W1989908968 @default.
- W3025296939 cites W1991245069 @default.
- W3025296939 cites W1992460009 @default.
- W3025296939 cites W1992549833 @default.
- W3025296939 cites W1995499476 @default.
- W3025296939 cites W1995954133 @default.
- W3025296939 cites W1997316605 @default.
- W3025296939 cites W1997653000 @default.
- W3025296939 cites W1999409403 @default.
- W3025296939 cites W2000819434 @default.
- W3025296939 cites W2000983409 @default.
- W3025296939 cites W2001929417 @default.
- W3025296939 cites W2004632928 @default.
- W3025296939 cites W2005781341 @default.
- W3025296939 cites W2006163951 @default.
- W3025296939 cites W2006982129 @default.
- W3025296939 cites W2007573212 @default.
- W3025296939 cites W2008545765 @default.
- W3025296939 cites W2011264397 @default.
- W3025296939 cites W2014166552 @default.
- W3025296939 cites W2014680491 @default.
- W3025296939 cites W2016326728 @default.
- W3025296939 cites W2016411107 @default.
- W3025296939 cites W2016905129 @default.
- W3025296939 cites W2017949036 @default.
- W3025296939 cites W2019744993 @default.
- W3025296939 cites W2024264840 @default.
- W3025296939 cites W2025981846 @default.
- W3025296939 cites W2026436880 @default.
- W3025296939 cites W2028808764 @default.
- W3025296939 cites W2035372169 @default.
- W3025296939 cites W2036597924 @default.
- W3025296939 cites W2036807646 @default.
- W3025296939 cites W2039225176 @default.
- W3025296939 cites W2039305820 @default.
- W3025296939 cites W2039825798 @default.
- W3025296939 cites W2040051585 @default.
- W3025296939 cites W2040689120 @default.
- W3025296939 cites W2042932723 @default.
- W3025296939 cites W2043418256 @default.
- W3025296939 cites W2044277639 @default.