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- W3031608643 abstract "ObjectiveTo investigate the clinical features of papillary thyroid microcarcinoma(PTMC) and the risk factors of central lymph node metastasis(CLNM) in PTMC patients.MethodsThe clinical data of 855 patients with PTMC who underwent prophylactic central lymph node dissection were retrospectively reviewed.ResultsIn the present study, the rate of CLNM was 21.9%(187/855) in PTMC patients.In the univariate analysis, the incidence of CLNM was significantly higher in male patients, age 5 mm, capsular invasion, multiple tumor and intracapsular spread(31.4% vs.19.5%, χ2=11.429, P=0.001; 29.3% vs.15.9%, χ2=22.416, P=0.000; 30.0% vs.14.3%, χ2=30.669, P=0.000; 29.4% vs.16.8%, χ2=19.233, P=0.000; 30.0% vs.19.9%, χ2=8.205, P=0.004; 42.9% vs.21.3%, χ2=5.549, P=0.018, respectively). Multivariate analysis showed that male gender, age 5mm, multiplicity and capsular invasion were independent risk factors for CLNM in PTMC patients(95% CI: 0.380-0.834, 0.349-0.693, 1.450-3.060, 1.078-2.229, 1.024-2.373, respectively).ConclusionA routine prophylactic central lymph node dissection should be considered particularly in male PTMC patients with age 5 mm, capsular invasion and tumor multiplicity.Key words: Thyroid neoplasms; Lymph node; Risk factors" @default.
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- W3031608643 date "2017-12-15" @default.
- W3031608643 modified "2023-09-24" @default.
- W3031608643 title "Risk factors for central lymph node metastasis in papillary thyroid microcarcinoma: an analysis of 855 patients" @default.
- W3031608643 doi "https://doi.org/10.3760/cma.j.issn.1008-6706.2017.24.003" @default.
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