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- W3032072142 abstract "ObjectiveTo report two cases of familial Gitelman syndrome and literature review regarding the updates of relevant genes, classification, treatment, and prognosis.MethodsThe clinical data of two sisters with Gitelman syndrome were retrospectively analyzed.ResultsTheir blood pressures were within normal range. Hypokalaemic alkalosis, hypomagnesemia, and hypocalciuria were corrected almost completely after three days of intravenous magnesium and potassium infusion, spirolactone and indometacin. However, the maintenance of normal potassium was unsuccessful over one year.ConclusionHypokalaemic alkalosis, hypomagnesemia, and hypocalciuria were normalized in Gitelman syndrome. There was some debate in regard to using PGE2 synthetase inhibitors. Tolerance of long-term medication will be the big challenge for curative effect.(Chin J Endocrinol Metab, 2015, 31: 1051-1054)Key words: Gitelman syndrome; Hypokalemia; Hypomagnesemia; Prognosis" @default.
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- W3032072142 date "2015-12-25" @default.
- W3032072142 modified "2023-09-24" @default.
- W3032072142 title "Diagnostic experience on familial Gitelman syndrome" @default.
- W3032072142 doi "https://doi.org/10.3760/cma.j.issn.1000-6699.2015.12.010" @default.
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