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- W3041409210 abstract "Numerous natural products have shown therapeutic effects as neuroprotective agents. Pharmacological studies revealed antioxidant, antiinflammatory, and cytoprotective properties for Nigella sativa (black cumin) and its components, in particular thymoquinone. On the other hand, there are several cellular, animal, and clinical reports of beneficial effects of this plant in different psychological and neurological models and disorders including anxiety, depression, psychosis, drug dependence, ischemia, memory impairment, epilepsy, neurotoxicity, neurodegeneration, and pain. Although antioxidant and antiinflammatory properties play critical roles in neuroprotective effects of N. sativa, but the modulation of different neurotransmitters, receptors, cellular factors, and signaling pathways are also involved in this herb's biological activities. In this chapter, we discuss about protective roles of N. sativa in different nervous system dysfunctions and the related mechanisms." @default.
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- W3041409210 date "2020-01-01" @default.
- W3041409210 modified "2023-10-13" @default.
- W3041409210 title "Nigella sativa L. and thymoquinone as neuroprotective antioxidants" @default.
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- W3041409210 doi "https://doi.org/10.1016/b978-0-12-817780-8.00021-9" @default.
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