FRINK Linked Data Fragments server

Matches in SemOpenAlex for { <https://semopenalex.org/work/W3043862034> ?p ?o ?g. }

• W3043862034 endingPage "e1060" @default.
• W3043862034 startingPage "e1038" @default.
• W3043862034 abstract "Oral rehydration solution (ORS) is a form of oral rehydration therapy (ORT) for diarrhoea that has the potential to drastically reduce child mortality; yet, according to UNICEF estimates, less than half of children younger than 5 years with diarrhoea in low-income and middle-income countries (LMICs) received ORS in 2016. A variety of recommended home fluids (RHF) exist as alternative forms of ORT; however, it is unclear whether RHF prevent child mortality. Previous studies have shown considerable variation between countries in ORS and RHF use, but subnational variation is unknown. This study aims to produce high-resolution geospatial estimates of relative and absolute coverage of ORS, RHF, and ORT (use of either ORS or RHF) in LMICs.We used a Bayesian geostatistical model including 15 spatial covariates and data from 385 household surveys across 94 LMICs to estimate annual proportions of children younger than 5 years of age with diarrhoea who received ORS or RHF (or both) on continuous continent-wide surfaces in 2000-17, and aggregated results to policy-relevant administrative units. Additionally, we analysed geographical inequality in coverage across administrative units and estimated the number of diarrhoeal deaths averted by increased coverage over the study period. Uncertainty in the mean coverage estimates was calculated by taking 250 draws from the posterior joint distribution of the model and creating uncertainty intervals (UIs) with the 2·5th and 97·5th percentiles of those 250 draws.While ORS use among children with diarrhoea increased in some countries from 2000 to 2017, coverage remained below 50% in the majority (62·6%; 12 417 of 19 823) of second administrative-level units and an estimated 6 519 000 children (95% UI 5 254 000-7 733 000) with diarrhoea were not treated with any form of ORT in 2017. Increases in ORS use corresponded with declines in RHF in many locations, resulting in relatively constant overall ORT coverage from 2000 to 2017. Although ORS was uniformly distributed subnationally in some countries, within-country geographical inequalities persisted in others; 11 countries had at least a 50% difference in one of their units compared with the country mean. Increases in ORS use over time were correlated with declines in RHF use and in diarrhoeal mortality in many locations, and an estimated 52 230 diarrhoeal deaths (36 910-68 860) were averted by scaling up of ORS coverage between 2000 and 2017. Finally, we identified key subnational areas in Colombia, Nigeria, and Sudan as examples of where diarrhoeal mortality remains higher than average, while ORS coverage remains lower than average.To our knowledge, this study is the first to produce and map subnational estimates of ORS, RHF, and ORT coverage and attributable child diarrhoeal deaths across LMICs from 2000 to 2017, allowing for tracking progress over time. Our novel results, combined with detailed subnational estimates of diarrhoeal morbidity and mortality, can support subnational needs assessments aimed at furthering policy makers' understanding of within-country disparities. Over 50 years after the discovery that led to this simple, cheap, and life-saving therapy, large gains in reducing mortality could still be made by reducing geographical inequalities in ORS coverage.Bill & Melinda Gates Foundation." @default.
• W3043862034 created "2020-07-29" @default.
• W3043862034 creator A5000035635 @default.
• W3043862034 creator A5000117442 @default.
• W3043862034 creator A5000168834 @default.
• W3043862034 creator A5000206745 @default.
• W3043862034 creator A5000338880 @default.
• W3043862034 creator A5000461763 @default.
• W3043862034 creator A5000740859 @default.
• W3043862034 creator A5001401729 @default.
• W3043862034 creator A5001707970 @default.
• W3043862034 creator A5002034400 @default.
• W3043862034 creator A5002168989 @default.
• W3043862034 creator A5002231508 @default.
• W3043862034 creator A5002356531 @default.
• W3043862034 creator A5002594031 @default.
• W3043862034 creator A5002608307 @default.
• W3043862034 creator A5002779288 @default.
• W3043862034 creator A5002983144 @default.
• W3043862034 creator A5003051173 @default.
• W3043862034 creator A5003138186 @default.
• W3043862034 creator A5003212611 @default.
• W3043862034 creator A5003235586 @default.
• W3043862034 creator A5003307319 @default.
• W3043862034 creator A5003417121 @default.
• W3043862034 creator A5003663671 @default.
• W3043862034 creator A5003745492 @default.
• W3043862034 creator A5003794185 @default.
• W3043862034 creator A5003826173 @default.
• W3043862034 creator A5003956314 @default.
• W3043862034 creator A5004166754 @default.
• W3043862034 creator A5004301018 @default.
• W3043862034 creator A5004515522 @default.
• W3043862034 creator A5004656526 @default.
• W3043862034 creator A5004703610 @default.
• W3043862034 creator A5004750721 @default.
• W3043862034 creator A5005033815 @default.
• W3043862034 creator A5005092080 @default.
• W3043862034 creator A5005386472 @default.
• W3043862034 creator A5005618787 @default.
• W3043862034 creator A5005629692 @default.
• W3043862034 creator A5005807534 @default.
• W3043862034 creator A5005934437 @default.
• W3043862034 creator A5005955225 @default.
• W3043862034 creator A5006130646 @default.
• W3043862034 creator A5006376693 @default.
• W3043862034 creator A5006522666 @default.
• W3043862034 creator A5006559853 @default.
• W3043862034 creator A5006632594 @default.
• W3043862034 creator A5006679078 @default.
• W3043862034 creator A5006820691 @default.
• W3043862034 creator A5006852274 @default.
• W3043862034 creator A5007166170 @default.
• W3043862034 creator A5007254252 @default.
• W3043862034 creator A5007331256 @default.
• W3043862034 creator A5007345041 @default.
• W3043862034 creator A5007444097 @default.
• W3043862034 creator A5007447653 @default.
• W3043862034 creator A5007517607 @default.
• W3043862034 creator A5007535248 @default.
• W3043862034 creator A5007642514 @default.
• W3043862034 creator A5007783906 @default.
• W3043862034 creator A5007975878 @default.
• W3043862034 creator A5007990024 @default.
• W3043862034 creator A5008056695 @default.
• W3043862034 creator A5008064001 @default.
• W3043862034 creator A5008189923 @default.
• W3043862034 creator A5008203658 @default.
• W3043862034 creator A5008428640 @default.
• W3043862034 creator A5008901021 @default.
• W3043862034 creator A5009019549 @default.
• W3043862034 creator A5009138922 @default.
• W3043862034 creator A5009244961 @default.
• W3043862034 creator A5009283382 @default.
• W3043862034 creator A5009289690 @default.
• W3043862034 creator A5009303759 @default.
• W3043862034 creator A5009365565 @default.
• W3043862034 creator A5009368855 @default.
• W3043862034 creator A5009474972 @default.
• W3043862034 creator A5009488482 @default.
• W3043862034 creator A5009509978 @default.
• W3043862034 creator A5009762734 @default.
• W3043862034 creator A5009772659 @default.
• W3043862034 creator A5010096865 @default.
• W3043862034 creator A5010157360 @default.
• W3043862034 creator A5010226052 @default.
• W3043862034 creator A5010247373 @default.
• W3043862034 creator A5010649271 @default.
• W3043862034 creator A5011276280 @default.
• W3043862034 creator A5011338774 @default.
• W3043862034 creator A5011663896 @default.
• W3043862034 creator A5011720417 @default.
• W3043862034 creator A5011782354 @default.
• W3043862034 creator A5011832138 @default.
• W3043862034 creator A5011996712 @default.
• W3043862034 creator A5012210914 @default.
• W3043862034 creator A5012325640 @default.
• W3043862034 creator A5012342368 @default.

• next