Matches in SemOpenAlex for { <https://semopenalex.org/work/W3080456770> ?p ?o ?g. }
- W3080456770 endingPage "152" @default.
- W3080456770 startingPage "152" @default.
- W3080456770 abstract "Fungal infections are a serious and increasing threat for human health, and one of the most frequent etiological agents for systemic mycoses is Candida spp. The gold standard to assess Candida virulence is the mouse model of systemic candidiasis, a restrictive, expensive, and time-consuming approach; therefore, invertebrate models have been proposed as alternatives. Galleria mellonella larvae have several traits that make them good candidates to study the fungal virulence. Here, we showed that a reduction in circulating hemocytes, increased melanin production, phenoloxidase, and lactate dehydrogenase activities were observed at 12 and 24 h postinoculation of highly virulent Candidatropicalis strains, while minimal changes in these parameters were observed in low-virulent strains. Similarly, the most virulent species Candida albicans, Candida tropicalis, Candida auris, Candida parapsilosis, and Candida orthopsilosis have led to significant changes in those parameters; while the low virulent species Candida guilliermondii, Candida krusei, and Candida metapsilosis induced modest variations in these immunological and cytotoxicity parameters. Since changes in circulating hemocytes, melanin production, phenoloxidase and lactate dehydrogenase activities showed a correlation with the larval median survival rates at 12 and 24 h postinoculation, we proposed them as candidates for early virulence predictors in G. mellonella." @default.
- W3080456770 created "2020-09-01" @default.
- W3080456770 creator A5009776467 @default.
- W3080456770 creator A5010622053 @default.
- W3080456770 creator A5045894964 @default.
- W3080456770 creator A5066366882 @default.
- W3080456770 creator A5068745008 @default.
- W3080456770 creator A5089035015 @default.
- W3080456770 creator A5089100795 @default.
- W3080456770 date "2020-08-27" @default.
- W3080456770 modified "2023-09-25" @default.
- W3080456770 title "Early Virulence Predictors during the Candida Species–Galleria mellonella Interaction" @default.
- W3080456770 cites W1536698017 @default.
- W3080456770 cites W1589917428 @default.
- W3080456770 cites W1598408991 @default.
- W3080456770 cites W1831371755 @default.
- W3080456770 cites W1841441806 @default.
- W3080456770 cites W1967112312 @default.
- W3080456770 cites W1980104121 @default.
- W3080456770 cites W1991044007 @default.
- W3080456770 cites W1992406210 @default.
- W3080456770 cites W1996687891 @default.
- W3080456770 cites W2007768935 @default.
- W3080456770 cites W2020702134 @default.
- W3080456770 cites W2038745630 @default.
- W3080456770 cites W2041471149 @default.
- W3080456770 cites W2044370709 @default.
- W3080456770 cites W2048054335 @default.
- W3080456770 cites W2053409140 @default.
- W3080456770 cites W2055629676 @default.
- W3080456770 cites W2060721894 @default.
- W3080456770 cites W2074473660 @default.
- W3080456770 cites W2096037926 @default.
- W3080456770 cites W2107794472 @default.
- W3080456770 cites W2110607326 @default.
- W3080456770 cites W2130346789 @default.
- W3080456770 cites W2144166731 @default.
- W3080456770 cites W2146057612 @default.
- W3080456770 cites W2154626064 @default.
- W3080456770 cites W2157673764 @default.
- W3080456770 cites W2166887993 @default.
- W3080456770 cites W2166909888 @default.
- W3080456770 cites W2171236269 @default.
- W3080456770 cites W2180240591 @default.
- W3080456770 cites W2242513489 @default.
- W3080456770 cites W2260381412 @default.
- W3080456770 cites W2299015152 @default.
- W3080456770 cites W2320092699 @default.
- W3080456770 cites W2490221580 @default.
- W3080456770 cites W2514801655 @default.
- W3080456770 cites W2549487014 @default.
- W3080456770 cites W2560464114 @default.
- W3080456770 cites W2730604177 @default.
- W3080456770 cites W2758263956 @default.
- W3080456770 cites W2759571352 @default.
- W3080456770 cites W2790584142 @default.
- W3080456770 cites W2800334052 @default.
- W3080456770 cites W2807227439 @default.
- W3080456770 cites W2892049897 @default.
- W3080456770 cites W2902839459 @default.
- W3080456770 cites W2905989696 @default.
- W3080456770 cites W2917995335 @default.
- W3080456770 cites W2920829599 @default.
- W3080456770 cites W2921240858 @default.
- W3080456770 cites W2926202803 @default.
- W3080456770 cites W2962874894 @default.
- W3080456770 cites W2990367772 @default.
- W3080456770 cites W2999106736 @default.
- W3080456770 cites W3011465664 @default.
- W3080456770 cites W3022308928 @default.
- W3080456770 cites W3023175438 @default.
- W3080456770 cites W3035089792 @default.
- W3080456770 doi "https://doi.org/10.3390/jof6030152" @default.
- W3080456770 hasPubMedCentralId "https://www.ncbi.nlm.nih.gov/pmc/articles/7559698" @default.
- W3080456770 hasPubMedId "https://pubmed.ncbi.nlm.nih.gov/32867152" @default.
- W3080456770 hasPublicationYear "2020" @default.
- W3080456770 type Work @default.
- W3080456770 sameAs 3080456770 @default.
- W3080456770 citedByCount "12" @default.
- W3080456770 countsByYear W30804567702020 @default.
- W3080456770 countsByYear W30804567702021 @default.
- W3080456770 countsByYear W30804567702022 @default.
- W3080456770 countsByYear W30804567702023 @default.
- W3080456770 crossrefType "journal-article" @default.
- W3080456770 hasAuthorship W3080456770A5009776467 @default.
- W3080456770 hasAuthorship W3080456770A5010622053 @default.
- W3080456770 hasAuthorship W3080456770A5045894964 @default.
- W3080456770 hasAuthorship W3080456770A5066366882 @default.
- W3080456770 hasAuthorship W3080456770A5068745008 @default.
- W3080456770 hasAuthorship W3080456770A5089035015 @default.
- W3080456770 hasAuthorship W3080456770A5089100795 @default.
- W3080456770 hasBestOaLocation W30804567701 @default.
- W3080456770 hasConcept C104317684 @default.
- W3080456770 hasConcept C107538193 @default.
- W3080456770 hasConcept C2775835631 @default.
- W3080456770 hasConcept C2779032433 @default.
- W3080456770 hasConcept C2779443200 @default.
- W3080456770 hasConcept C2780670043 @default.