Matches in SemOpenAlex for { <https://semopenalex.org/work/W3121325186> ?p ?o ?g. }
Showing items 1 to 67 of
67
with 100 items per page.
- W3121325186 abstract "Major advances have already been made in Rheumatology, many of which have translated into improved clinical care and management. These have largely centred around: Descriptive studies. These have resulted in: a better classification/diagnosis and thus treatment of rheumatic conditions a clearer understanding of the natural history of diseases epidemiologically defined disease parameters (e.g. prevalence, incidence, geographical distribution, age at onset, gender ratios) Imaging and definition of relevant laboratory tests higher resolution imaging of hard and soft tissues for appreciating both early disease processes and disease progression/severity. Laboratory investigations, as useful aids for diagnosis (autoantibody profiles, rheumatoid factor) and disease activity (e.g. CRP) Treatments and interventions The development of effective and lasting joint replacement prostheses The introduction of better treatments (e.g. Cox2 inhibitors) and biological based therapies to antagonise inflammatory cytokines and processes (e.g. TNF-alpha antagonists) What can be expected in the future for rheumatology remains speculation but exciting prospects are likely for clinical medicine in the post human genome sequencing era. A primary objective will be the identification of the genetic and environmental components to disease aetiopathogenesis. These should lead to: a better understanding of disease processes and classification resulting in more appropriate treatments. The identification of novel targets for pharmaceutical intervention. An ability to predict disease risk and disease outcome, permiting early screening and a more rapid or aggressive treatment plan. The characterisation of gene-environment interactions, resulting in health education and changes in life style or in possible proplylactic intervention. The identification of the pharmacogenetic basis for response to drugs and why there is variation in efficacy or adverse drug reactions. This should lead to personalised medicine. New developments in molecular biology and cell biology are also likely to impinge on rheumatology in the areas of: Tissue Engineering Gene therapy Stem cell transplation" @default.
- W3121325186 created "2021-02-01" @default.
- W3121325186 creator A5086038118 @default.
- W3121325186 date "2001-06-01" @default.
- W3121325186 modified "2023-09-23" @default.
- W3121325186 title "SP0037 What has been achieved and what can be expected in rheumatology?" @default.
- W3121325186 doi "https://doi.org/10.1136/annrheumdis-2001.89" @default.
- W3121325186 hasPublicationYear "2001" @default.
- W3121325186 type Work @default.
- W3121325186 sameAs 3121325186 @default.
- W3121325186 citedByCount "0" @default.
- W3121325186 crossrefType "proceedings-article" @default.
- W3121325186 hasAuthorship W3121325186A5086038118 @default.
- W3121325186 hasBestOaLocation W31213251861 @default.
- W3121325186 hasConcept C118552586 @default.
- W3121325186 hasConcept C126322002 @default.
- W3121325186 hasConcept C170734499 @default.
- W3121325186 hasConcept C177713679 @default.
- W3121325186 hasConcept C198451711 @default.
- W3121325186 hasConcept C27415008 @default.
- W3121325186 hasConcept C2777575956 @default.
- W3121325186 hasConcept C2779134260 @default.
- W3121325186 hasConcept C2780665704 @default.
- W3121325186 hasConcept C60644358 @default.
- W3121325186 hasConcept C71924100 @default.
- W3121325186 hasConcept C86803240 @default.
- W3121325186 hasConcept C98274493 @default.
- W3121325186 hasConceptScore W3121325186C118552586 @default.
- W3121325186 hasConceptScore W3121325186C126322002 @default.
- W3121325186 hasConceptScore W3121325186C170734499 @default.
- W3121325186 hasConceptScore W3121325186C177713679 @default.
- W3121325186 hasConceptScore W3121325186C198451711 @default.
- W3121325186 hasConceptScore W3121325186C27415008 @default.
- W3121325186 hasConceptScore W3121325186C2777575956 @default.
- W3121325186 hasConceptScore W3121325186C2779134260 @default.
- W3121325186 hasConceptScore W3121325186C2780665704 @default.
- W3121325186 hasConceptScore W3121325186C60644358 @default.
- W3121325186 hasConceptScore W3121325186C71924100 @default.
- W3121325186 hasConceptScore W3121325186C86803240 @default.
- W3121325186 hasConceptScore W3121325186C98274493 @default.
- W3121325186 hasLocation W31213251861 @default.
- W3121325186 hasOpenAccess W3121325186 @default.
- W3121325186 hasPrimaryLocation W31213251861 @default.
- W3121325186 hasRelatedWork W120443491 @default.
- W3121325186 hasRelatedWork W1987115454 @default.
- W3121325186 hasRelatedWork W2029351439 @default.
- W3121325186 hasRelatedWork W2066813673 @default.
- W3121325186 hasRelatedWork W2113312452 @default.
- W3121325186 hasRelatedWork W2129362188 @default.
- W3121325186 hasRelatedWork W2135095259 @default.
- W3121325186 hasRelatedWork W2170668284 @default.
- W3121325186 hasRelatedWork W2240575228 @default.
- W3121325186 hasRelatedWork W2253866030 @default.
- W3121325186 hasRelatedWork W2328041492 @default.
- W3121325186 hasRelatedWork W2414540464 @default.
- W3121325186 hasRelatedWork W2542343578 @default.
- W3121325186 hasRelatedWork W2623123140 @default.
- W3121325186 hasRelatedWork W2770901328 @default.
- W3121325186 hasRelatedWork W2799690462 @default.
- W3121325186 hasRelatedWork W2873812536 @default.
- W3121325186 hasRelatedWork W3003805058 @default.
- W3121325186 hasRelatedWork W3011344727 @default.
- W3121325186 hasRelatedWork W3038739807 @default.
- W3121325186 isParatext "false" @default.
- W3121325186 isRetracted "false" @default.
- W3121325186 magId "3121325186" @default.
- W3121325186 workType "article" @default.