Matches in SemOpenAlex for { <https://semopenalex.org/work/W3133729913> ?p ?o ?g. }
Showing items 1 to 63 of
63
with 100 items per page.
- W3133729913 endingPage "51" @default.
- W3133729913 startingPage "51" @default.
- W3133729913 abstract "Context: Coronary artery disease (CAD) occurs as a consequence of dyslipidemia and chronic inflammation. Cardiovascular disease mortality is on the rise in India. Aims: Explore the utility of simple markers such as neutrophil-to-lymphocyte ratio (NLR) and triglyceride/high-density lipoprotein cholesterol (TG/HDLc) ratio, to study the extent of coronary lesions as seen on angiography. Settings and Design: Observational study in a tertiary-care hospital in North-India. Methodology: Coronary angiograms of 126 outpatients were graded as per Friesinger Index. Lipid profile was analyzed for each patient, along with complete blood count parameters, including total leukocyte count (TLC), absolute neutrophil, and lymphocyte counts and mean platelet volume (MPV). Statistical Analysis Used:Comparison of groups was done using a Mann–Whitney U test, of continuous variables using a correlation coefficient, and of categorical variables using a Chi-square test, and odds ratios were estimated. Receiver operator characteristic curves were constructed, and cutoffs were obtained. Results: TG/HDLc-ratio was associated with severe coronary lesions (Friesinger-Index ≥5) [odds ratio (OR): 3.46; 95% confidence interval (CI): 1.32–9.10], which was stronger than the association of TG [OR: 3.15; 95%CI: 1.33–7.42] or HDLc [OR: 1.86; 95%CI: 0.81–3.82] alone. No association existed for total or low-density lipoprotein cholesterol. NLR was significantly higher among patients with severe lesions. NLR and MPV were significantly correlated with TG/HDLc ratio. Area under curve for TG/HDLc ratio and NLR was 73.7 and 60.8. Cutoff values were 2.53 (Sensitivity (SN) = 83.1%, Specificity (SP) = 56.7%) and 1.84 (SN = 61.0%, SP = 49.3%), respectively. Conclusions: TG/HDLc ratio and NLR are associated with CAD severity, more so than TG or HDLc alone, or TLC. They are easily accessible and inexpensive markers that may be utilized in identifying patients at risk for heart disease." @default.
- W3133729913 created "2021-03-15" @default.
- W3133729913 creator A5023373790 @default.
- W3133729913 creator A5032552563 @default.
- W3133729913 creator A5041430959 @default.
- W3133729913 creator A5081595508 @default.
- W3133729913 date "2020-01-01" @default.
- W3133729913 modified "2023-10-18" @default.
- W3133729913 title "Utility of neutrophil-to-lymphocyte ratio, triglycerides, and high-density lipoprotein cholesterol in assessing the severity of coronary artery disease" @default.
- W3133729913 doi "https://doi.org/10.4103/jcpc.jcpc_7_20" @default.
- W3133729913 hasPublicationYear "2020" @default.
- W3133729913 type Work @default.
- W3133729913 sameAs 3133729913 @default.
- W3133729913 citedByCount "2" @default.
- W3133729913 countsByYear W31337299132022 @default.
- W3133729913 countsByYear W31337299132023 @default.
- W3133729913 crossrefType "journal-article" @default.
- W3133729913 hasAuthorship W3133729913A5023373790 @default.
- W3133729913 hasAuthorship W3133729913A5032552563 @default.
- W3133729913 hasAuthorship W3133729913A5041430959 @default.
- W3133729913 hasAuthorship W3133729913A5081595508 @default.
- W3133729913 hasBestOaLocation W31337299131 @default.
- W3133729913 hasConcept C126322002 @default.
- W3133729913 hasConcept C164705383 @default.
- W3133729913 hasConcept C2777761686 @default.
- W3133729913 hasConcept C2778163477 @default.
- W3133729913 hasConcept C2778213512 @default.
- W3133729913 hasConcept C2778963024 @default.
- W3133729913 hasConcept C2779134260 @default.
- W3133729913 hasConcept C2780072125 @default.
- W3133729913 hasConcept C2780541478 @default.
- W3133729913 hasConcept C71924100 @default.
- W3133729913 hasConceptScore W3133729913C126322002 @default.
- W3133729913 hasConceptScore W3133729913C164705383 @default.
- W3133729913 hasConceptScore W3133729913C2777761686 @default.
- W3133729913 hasConceptScore W3133729913C2778163477 @default.
- W3133729913 hasConceptScore W3133729913C2778213512 @default.
- W3133729913 hasConceptScore W3133729913C2778963024 @default.
- W3133729913 hasConceptScore W3133729913C2779134260 @default.
- W3133729913 hasConceptScore W3133729913C2780072125 @default.
- W3133729913 hasConceptScore W3133729913C2780541478 @default.
- W3133729913 hasConceptScore W3133729913C71924100 @default.
- W3133729913 hasIssue "2" @default.
- W3133729913 hasLocation W31337299131 @default.
- W3133729913 hasOpenAccess W3133729913 @default.
- W3133729913 hasPrimaryLocation W31337299131 @default.
- W3133729913 hasRelatedWork W111424409 @default.
- W3133729913 hasRelatedWork W1915623690 @default.
- W3133729913 hasRelatedWork W1999076944 @default.
- W3133729913 hasRelatedWork W2004682325 @default.
- W3133729913 hasRelatedWork W2006507414 @default.
- W3133729913 hasRelatedWork W2012398428 @default.
- W3133729913 hasRelatedWork W2020629107 @default.
- W3133729913 hasRelatedWork W2025491152 @default.
- W3133729913 hasRelatedWork W2058420421 @default.
- W3133729913 hasRelatedWork W2063677317 @default.
- W3133729913 hasVolume "9" @default.
- W3133729913 isParatext "false" @default.
- W3133729913 isRetracted "false" @default.
- W3133729913 magId "3133729913" @default.
- W3133729913 workType "article" @default.