FRINK Linked Data Fragments server

Matches in SemOpenAlex for { <https://semopenalex.org/work/W3156644904> ?p ?o ?g. }

• W3156644904 endingPage "788" @default.
• W3156644904 startingPage "781" @default.
• W3156644904 abstract "Abstract Aim Diagnosing and monitoring vascular activity in giant cell arteritis (GCA) is difficult due to the paucity of specific serological biomarkers. We assessed the utility of 8 novel biomarkers in an inception cohort of newly suspected GCA patients. Method Consecutive patients were enrolled between May 2016 and December 2017. Serum was collected within 72 hours of commencing corticosteroids and at 6 months. It was analyzed for levels of intra‐cellular adhesion molecule 1, vascular endothelial growth factor (VEGF), pentraxin 3, von Willebrand factor and procalcitonin (5‐plex R&D Systems multiplex assay) and interleukin (IL)6, IL12 and interferon‐γ (high‐sensitivity 3‐plex ProcartaPlex multiplex assay). A GCA specific positron emission tomography / computed tomography (PET/CT) scan was performed at enrolment with uptake in each vascular territory graded and summed to derive a total vascular score (TVS). Results For the 63 patients enrolled, 12 (19%) had a final diagnosis of biopsy‐positive GCA and a further 9 had a clinical diagnosis of biopsy‐negative GCA. None of the 8 biomarkers was significantly higher in GCA patients compared with those with alternative diagnoses, or demonstrated a positive correlation with the PET/CT TVS. This was in contrast to the C‐reactive protein (CRP) and erythrocyte sedimentation rate (ESR) which were higher in the biopsy‐positive GCA cohort ( P < .04) and showed weak positive correlations with the TVS (correlation coefficient 0.34, P < .01). Procalcitonin did not distinguish between GCA and infection. Concentrations of CRP, ESR, VEGF and pentraxin 3 decreased between diagnosis and 6 months in GCA patients. Conclusion This study did not identify new serological biomarkers to assist in diagnosing or assessing the vasculitis burden in GCA." @default.
• W3156644904 created "2021-04-26" @default.
• W3156644904 creator A5005689053 @default.
• W3156644904 creator A5012952846 @default.
• W3156644904 creator A5018497193 @default.
• W3156644904 creator A5035763329 @default.
• W3156644904 creator A5038039654 @default.
• W3156644904 creator A5048465771 @default.
• W3156644904 creator A5050063439 @default.
• W3156644904 date "2021-04-13" @default.
• W3156644904 modified "2023-10-14" @default.
• W3156644904 title "Limited utility of novel serological biomarkers in patients newly suspected of having giant cell arteritis" @default.
• W3156644904 cites W1963972792 @default.
• W3156644904 cites W1964525131 @default.
• W3156644904 cites W1974619073 @default.
• W3156644904 cites W1980934541 @default.
• W3156644904 cites W1982721909 @default.
• W3156644904 cites W1986469214 @default.
• W3156644904 cites W1987316799 @default.
• W3156644904 cites W2007175406 @default.
• W3156644904 cites W2019754280 @default.
• W3156644904 cites W2051715499 @default.
• W3156644904 cites W2060888599 @default.
• W3156644904 cites W2081794593 @default.
• W3156644904 cites W2086238123 @default.
• W3156644904 cites W2086465769 @default.
• W3156644904 cites W2093961109 @default.
• W3156644904 cites W2116148601 @default.
• W3156644904 cites W2127445888 @default.
• W3156644904 cites W2131526886 @default.
• W3156644904 cites W2132732628 @default.
• W3156644904 cites W2144768521 @default.
• W3156644904 cites W2148177365 @default.
• W3156644904 cites W2156080097 @default.
• W3156644904 cites W2318380925 @default.
• W3156644904 cites W2557290160 @default.
• W3156644904 cites W2581552068 @default.
• W3156644904 cites W2597945615 @default.
• W3156644904 cites W2606382560 @default.
• W3156644904 cites W2620452493 @default.
• W3156644904 cites W2737436316 @default.
• W3156644904 cites W2761236748 @default.
• W3156644904 cites W2888309042 @default.
• W3156644904 cites W2913203620 @default.
• W3156644904 cites W2922026966 @default.
• W3156644904 cites W2947522909 @default.
• W3156644904 cites W2954943567 @default.
• W3156644904 cites W2974178577 @default.
• W3156644904 doi "https://doi.org/10.1111/1756-185x.14111" @default.
• W3156644904 hasPubMedId "https://pubmed.ncbi.nlm.nih.gov/33847438" @default.
• W3156644904 hasPublicationYear "2021" @default.
• W3156644904 type Work @default.
• W3156644904 sameAs 3156644904 @default.
• W3156644904 citedByCount "3" @default.
• W3156644904 countsByYear W31566449042022 @default.
• W3156644904 crossrefType "journal-article" @default.
• W3156644904 hasAuthorship W3156644904A5005689053 @default.
• W3156644904 hasAuthorship W3156644904A5012952846 @default.
• W3156644904 hasAuthorship W3156644904A5018497193 @default.
• W3156644904 hasAuthorship W3156644904A5035763329 @default.
• W3156644904 hasAuthorship W3156644904A5038039654 @default.
• W3156644904 hasAuthorship W3156644904A5048465771 @default.
• W3156644904 hasAuthorship W3156644904A5050063439 @default.
• W3156644904 hasConcept C10936531 @default.
• W3156644904 hasConcept C126322002 @default.
• W3156644904 hasConcept C126838900 @default.
• W3156644904 hasConcept C142724271 @default.
• W3156644904 hasConcept C159654299 @default.
• W3156644904 hasConcept C203014093 @default.
• W3156644904 hasConcept C2775842073 @default.
• W3156644904 hasConcept C2775934546 @default.
• W3156644904 hasConcept C2776015282 @default.
• W3156644904 hasConcept C2776712624 @default.
• W3156644904 hasConcept C2778143017 @default.
• W3156644904 hasConcept C2778384902 @default.
• W3156644904 hasConcept C2779134260 @default.
• W3156644904 hasConcept C45189115 @default.
• W3156644904 hasConcept C71924100 @default.
• W3156644904 hasConcept C72563966 @default.
• W3156644904 hasConcept C90924648 @default.
• W3156644904 hasConceptScore W3156644904C10936531 @default.
• W3156644904 hasConceptScore W3156644904C126322002 @default.
• W3156644904 hasConceptScore W3156644904C126838900 @default.
• W3156644904 hasConceptScore W3156644904C142724271 @default.
• W3156644904 hasConceptScore W3156644904C159654299 @default.
• W3156644904 hasConceptScore W3156644904C203014093 @default.
• W3156644904 hasConceptScore W3156644904C2775842073 @default.
• W3156644904 hasConceptScore W3156644904C2775934546 @default.
• W3156644904 hasConceptScore W3156644904C2776015282 @default.
• W3156644904 hasConceptScore W3156644904C2776712624 @default.
• W3156644904 hasConceptScore W3156644904C2778143017 @default.
• W3156644904 hasConceptScore W3156644904C2778384902 @default.
• W3156644904 hasConceptScore W3156644904C2779134260 @default.
• W3156644904 hasConceptScore W3156644904C45189115 @default.
• W3156644904 hasConceptScore W3156644904C71924100 @default.
• W3156644904 hasConceptScore W3156644904C72563966 @default.
• W3156644904 hasConceptScore W3156644904C90924648 @default.
• W3156644904 hasIssue "6" @default.

• next