FRINK Linked Data Fragments server

Matches in SemOpenAlex for { <https://semopenalex.org/work/W3210366315> ?p ?o ?g. }

• W3210366315 endingPage "106458" @default.
• W3210366315 startingPage "106458" @default.
• W3210366315 abstract "Concerns regarding carbapenem-resistant Klebsiella pneumoniae (CR-Kp), especially in bloodstream infections (BSIs), are continuing to increase worldwide. Several novel agents with activity against BSI CR-Kp have been approved or are in late-stage clinical development. In this study, the antibacterial effects of ceftazidime/avibactam (CZA), aztreonam/avibactam (AZA), meropenem/vaborbactam (MEV), imipenem-cilastatin/relebactam (ICR) and eravacycline (ERV) against three colistin-resistant CR-Kp (COLR-Kp) and four CZA-resistant CR-Kp (CZAR-Kp) were tested by time-kill assay. Klebsiella pneumoniae ATCC® BAA-1705TM was used as a control strain. Two COLR-Kp isolates carried the blaKPC-2 gene and four CAZR-Kp isolates carried metallo-β-lactamase genes. The results revealed that ERV resulted in re-growth of seven tested isolates. CZA and MEV showed a bactericidal effect against isolates harbouring blaKPC-2. ICR reduced the population of six isolates to >5 log10 CFU/mL compared with the initial count. AZA showed a bactericidal effect (>5 log10 CFU/mL) against seven isolates and a bacteriostatic effect (<3 log10 CFU/mL) against one CZAR-Kp isolate. Therefore, AZA and ICR are effective therapeutic candidates for COLR-Kp and CZAR-Kp isolates." @default.
• W3210366315 created "2021-11-08" @default.
• W3210366315 creator A5011995502 @default.
• W3210366315 creator A5024809872 @default.
• W3210366315 creator A5025761377 @default.
• W3210366315 creator A5027440092 @default.
• W3210366315 creator A5055916244 @default.
• W3210366315 creator A5058306932 @default.
• W3210366315 creator A5084728355 @default.
• W3210366315 date "2021-12-01" @default.
• W3210366315 modified "2023-10-18" @default.
• W3210366315 title "New options for bloodstream infections caused by colistin‐ or ceftazidime/avibactam‐resistant Klebsiella pneumoniae" @default.
• W3210366315 cites W1990290615 @default.
• W3210366315 cites W2024263059 @default.
• W3210366315 cites W2094936149 @default.
• W3210366315 cites W2116637970 @default.
• W3210366315 cites W2377467382 @default.
• W3210366315 cites W2618911885 @default.
• W3210366315 cites W2712120856 @default.
• W3210366315 cites W2783246132 @default.
• W3210366315 cites W2888520542 @default.
• W3210366315 cites W2891577800 @default.
• W3210366315 cites W2918608884 @default.
• W3210366315 cites W2940595256 @default.
• W3210366315 cites W2943594574 @default.
• W3210366315 cites W2978732478 @default.
• W3210366315 cites W2995664785 @default.
• W3210366315 cites W2997554990 @default.
• W3210366315 cites W3007464332 @default.
• W3210366315 cites W3088074710 @default.
• W3210366315 cites W3106009346 @default.
• W3210366315 cites W3130651206 @default.
• W3210366315 doi "https://doi.org/10.1016/j.ijantimicag.2021.106458" @default.
• W3210366315 hasPubMedId "https://pubmed.ncbi.nlm.nih.gov/34706255" @default.
• W3210366315 hasPublicationYear "2021" @default.
• W3210366315 type Work @default.
• W3210366315 sameAs 3210366315 @default.
• W3210366315 citedByCount "3" @default.
• W3210366315 countsByYear W32103663152022 @default.
• W3210366315 countsByYear W32103663152023 @default.
• W3210366315 crossrefType "journal-article" @default.
• W3210366315 hasAuthorship W3210366315A5011995502 @default.
• W3210366315 hasAuthorship W3210366315A5024809872 @default.
• W3210366315 hasAuthorship W3210366315A5025761377 @default.
• W3210366315 hasAuthorship W3210366315A5027440092 @default.
• W3210366315 hasAuthorship W3210366315A5055916244 @default.
• W3210366315 hasAuthorship W3210366315A5058306932 @default.
• W3210366315 hasAuthorship W3210366315A5084728355 @default.
• W3210366315 hasBestOaLocation W32103663151 @default.
• W3210366315 hasConcept C104317684 @default.
• W3210366315 hasConcept C2775933652 @default.
• W3210366315 hasConcept C2776968632 @default.
• W3210366315 hasConcept C2777058267 @default.
• W3210366315 hasConcept C2777406300 @default.
• W3210366315 hasConcept C2777637488 @default.
• W3210366315 hasConcept C2779259085 @default.
• W3210366315 hasConcept C2779631663 @default.
• W3210366315 hasConcept C2780416669 @default.
• W3210366315 hasConcept C2908647359 @default.
• W3210366315 hasConcept C501593827 @default.
• W3210366315 hasConcept C523546767 @default.
• W3210366315 hasConcept C54355233 @default.
• W3210366315 hasConcept C547475151 @default.
• W3210366315 hasConcept C55493867 @default.
• W3210366315 hasConcept C71924100 @default.
• W3210366315 hasConcept C86803240 @default.
• W3210366315 hasConcept C89423630 @default.
• W3210366315 hasConcept C94665300 @default.
• W3210366315 hasConcept C99454951 @default.
• W3210366315 hasConceptScore W3210366315C104317684 @default.
• W3210366315 hasConceptScore W3210366315C2775933652 @default.
• W3210366315 hasConceptScore W3210366315C2776968632 @default.
• W3210366315 hasConceptScore W3210366315C2777058267 @default.
• W3210366315 hasConceptScore W3210366315C2777406300 @default.
• W3210366315 hasConceptScore W3210366315C2777637488 @default.
• W3210366315 hasConceptScore W3210366315C2779259085 @default.
• W3210366315 hasConceptScore W3210366315C2779631663 @default.
• W3210366315 hasConceptScore W3210366315C2780416669 @default.
• W3210366315 hasConceptScore W3210366315C2908647359 @default.
• W3210366315 hasConceptScore W3210366315C501593827 @default.
• W3210366315 hasConceptScore W3210366315C523546767 @default.
• W3210366315 hasConceptScore W3210366315C54355233 @default.
• W3210366315 hasConceptScore W3210366315C547475151 @default.
• W3210366315 hasConceptScore W3210366315C55493867 @default.
• W3210366315 hasConceptScore W3210366315C71924100 @default.
• W3210366315 hasConceptScore W3210366315C86803240 @default.
• W3210366315 hasConceptScore W3210366315C89423630 @default.
• W3210366315 hasConceptScore W3210366315C94665300 @default.
• W3210366315 hasConceptScore W3210366315C99454951 @default.
• W3210366315 hasIssue "6" @default.
• W3210366315 hasLocation W32103663151 @default.
• W3210366315 hasLocation W32103663152 @default.
• W3210366315 hasOpenAccess W3210366315 @default.
• W3210366315 hasPrimaryLocation W32103663151 @default.
• W3210366315 hasRelatedWork W2259669282 @default.
• W3210366315 hasRelatedWork W2611008308 @default.
• W3210366315 hasRelatedWork W2769299598 @default.
• W3210366315 hasRelatedWork W2901057130 @default.

• next