Matches in SemOpenAlex for { <https://semopenalex.org/work/W4253704677> ?p ?o ?g. }
Showing items 1 to 69 of
69
with 100 items per page.
- W4253704677 abstract "Abstract BackgroundThe results of different studies have indicated the possible associations of TLR4 and IL-8 genes polymorphisms with Age-Related Macular Degeneration (AMD). A meta-analysis study was designed to evaluate the possible associations of TLR4 and IL-8 genes polymorphisms with Age-Related Macular Degeneration (AMD). MethodA systematic literature search was carried out in PubMed, Embase, Web of Science, and Scopus databases to identify relevant publications. Pooled Odds Ratio (OR) with 95% Confidence Interval (CI) was used to evaluate the power of association.ResultsA total of 12 case-control studies with 4804 AMD patients and 4422 healthy controls were included in this meta-analysis. We found significant associations under the genotypic and allelic models of TLR4/rs4986790 (AA vs. AG+GG: OR=0.73 [0.55-0.97], P =0.03; and AA vs. AG: OR=0.71 [0.53-0.95], P =0.02) and IL-8/rs2227306 (TT vs. CC: OR=1.63 [1.04-2.56], P =0.03; CC vs. TT+TC: OR=0.62 [0.48-0.80], P <0.001; CC vs. TC: OR=0.65 [0.47-0.89], P =0.007; and C vs. T: OR=0.71 [0.64-0.78], P <0.001). However, the data from this meta-analysis declined the associations of TLR4/rs4986791 and IL-8/rs4073 polymorphisms.ConclusionThe current meta-analysis study suggested that IL-8/rs2227306 and TLR4/rs4986790 polymorphisms are associated with susceptibility to AMD." @default.
- W4253704677 created "2022-05-12" @default.
- W4253704677 creator A5003177674 @default.
- W4253704677 creator A5022150802 @default.
- W4253704677 creator A5048044414 @default.
- W4253704677 creator A5077752521 @default.
- W4253704677 creator A5081807123 @default.
- W4253704677 creator A5082639261 @default.
- W4253704677 date "2020-10-01" @default.
- W4253704677 modified "2023-10-16" @default.
- W4253704677 title "Associations of TLR4 and IL-8 genes polymorphisms with Age-related macular degeneration (AMD): a systematic review and meta-analysis" @default.
- W4253704677 doi "https://doi.org/10.21203/rs.3.rs-83170/v1" @default.
- W4253704677 hasPublicationYear "2020" @default.
- W4253704677 type Work @default.
- W4253704677 citedByCount "0" @default.
- W4253704677 crossrefType "posted-content" @default.
- W4253704677 hasAuthorship W4253704677A5003177674 @default.
- W4253704677 hasAuthorship W4253704677A5022150802 @default.
- W4253704677 hasAuthorship W4253704677A5048044414 @default.
- W4253704677 hasAuthorship W4253704677A5077752521 @default.
- W4253704677 hasAuthorship W4253704677A5081807123 @default.
- W4253704677 hasAuthorship W4253704677A5082639261 @default.
- W4253704677 hasBestOaLocation W42537046771 @default.
- W4253704677 hasConcept C104317684 @default.
- W4253704677 hasConcept C118487528 @default.
- W4253704677 hasConcept C126322002 @default.
- W4253704677 hasConcept C135763542 @default.
- W4253704677 hasConcept C143998085 @default.
- W4253704677 hasConcept C156957248 @default.
- W4253704677 hasConcept C180754005 @default.
- W4253704677 hasConcept C2776403814 @default.
- W4253704677 hasConcept C44249647 @default.
- W4253704677 hasConcept C54355233 @default.
- W4253704677 hasConcept C60644358 @default.
- W4253704677 hasConcept C71924100 @default.
- W4253704677 hasConcept C86803240 @default.
- W4253704677 hasConcept C90924648 @default.
- W4253704677 hasConcept C95190672 @default.
- W4253704677 hasConceptScore W4253704677C104317684 @default.
- W4253704677 hasConceptScore W4253704677C118487528 @default.
- W4253704677 hasConceptScore W4253704677C126322002 @default.
- W4253704677 hasConceptScore W4253704677C135763542 @default.
- W4253704677 hasConceptScore W4253704677C143998085 @default.
- W4253704677 hasConceptScore W4253704677C156957248 @default.
- W4253704677 hasConceptScore W4253704677C180754005 @default.
- W4253704677 hasConceptScore W4253704677C2776403814 @default.
- W4253704677 hasConceptScore W4253704677C44249647 @default.
- W4253704677 hasConceptScore W4253704677C54355233 @default.
- W4253704677 hasConceptScore W4253704677C60644358 @default.
- W4253704677 hasConceptScore W4253704677C71924100 @default.
- W4253704677 hasConceptScore W4253704677C86803240 @default.
- W4253704677 hasConceptScore W4253704677C90924648 @default.
- W4253704677 hasConceptScore W4253704677C95190672 @default.
- W4253704677 hasLocation W42537046771 @default.
- W4253704677 hasOpenAccess W4253704677 @default.
- W4253704677 hasPrimaryLocation W42537046771 @default.
- W4253704677 hasRelatedWork W11388833 @default.
- W4253704677 hasRelatedWork W13726115 @default.
- W4253704677 hasRelatedWork W14265451 @default.
- W4253704677 hasRelatedWork W15630781 @default.
- W4253704677 hasRelatedWork W19713832 @default.
- W4253704677 hasRelatedWork W3991422 @default.
- W4253704677 hasRelatedWork W4275784 @default.
- W4253704677 hasRelatedWork W4845270 @default.
- W4253704677 hasRelatedWork W674087 @default.
- W4253704677 hasRelatedWork W8554529 @default.
- W4253704677 isParatext "false" @default.
- W4253704677 isRetracted "false" @default.
- W4253704677 workType "article" @default.