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- W4288687323 abstract "Abstract Background Endovascular therapy (ET) for delayed post-pancreatectomy hemorrhage (PPH) involves the risk of hepatic artery occlusion (HAO). Nonetheless, the development of extrahepatic collateral circulation (EHC) and relationship between radiological factors (EHC, portal vein stenosis, and HAO) and adverse hepatic events after ET remain unclear. This study aimed to evaluate the efficacy and safety of ET for delayed PPH and examine the development of EHC. Methods A total of 19 ET cases for delayed PPH were reviewed. Hepatic adverse events, portal vein stenosis, HAO, and mortality rate after ET were evaluated. Moreover, EHC from the left gastric artery (LGA), right inferior phrenic artery (RIPA), left inferior phrenic artery (LIPA), right internal thoracic artery (RITA), left internal thoracic artery (LITA), renal artery (RA), omental artery (OA), intercostal artery (IA), and branch of superior mesenteric artery (BSMA) was assessed using angiogram and computed tomography angiography (CTA). Results All cases were successfully treated using transcatheter arterial embolization (n = 17) and stent-graft placement (n = 2) without mortality. EHC from the LGA (8/19), RIPA (10/19), LIPA (4/19), and RITA (3/19) was observed on post-ET CTA. The incidence of hepatic adverse event was significant in the group with both HAO and portal vein stenosis (p < 0.001) and absence of EHC from LIPA and RITA (p < 0.05). Conclusion ET for delayed PPH might be effective and safe. While avoiding both HAO and portal vein stenosis is important, the development of EHCs from LIPA and RITA may prevent hepatic adverse events after ET." @default.
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- W4288687323 date "2022-07-29" @default.
- W4288687323 modified "2023-09-27" @default.
- W4288687323 title "Development of extrahepatic collateral circulation after endovascular therapy for post-pancreatectomy hemorrhage" @default.
- W4288687323 doi "https://doi.org/10.21203/rs.3.rs-1833413/v1" @default.
- W4288687323 hasPublicationYear "2022" @default.
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